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Other Rheumatic Conditions

How to Recognize an Autoinflammatory Disorder

Samantha C. Shapiro, MD  |  June 15, 2022

Autoinflammatory disorders may involve genetic mutations of the inflammasome or an environmental trigger in a genetically susceptible host. Dr. Jay Mehta discussed a practical, clinical approach to caring for patients with autoinflammatory disorders, such as periodic fever syndromes, during the 2022 ACR Education Exchange.

Bernard Chantal / shutterstock.com

Diagnostic Challenges of MIS-C

Brian L.P. Dizon, MD, PhD, & Sangeeta Sule, MD, PhD  |  May 12, 2022

During the peak of the coronavirus pandemic in Washington, D.C., we were asked to evaluate a 14-year-old boy admitted to the pediatric hospitalist service. He had been healthy until two weeks before, when he noted a sore throat, and soon after he developed fevers and rashes without congestion, shortness of breath, conjunctivitis or swollen lymph…

Case Report: Pulmonary Sarcoid-Like Reaction in Patient Treated with Etanercept

Luis Lora Garcia, MD, Sneha Centala, MD, MS, Gitanjali Lobo, MD, Shahla Mallick, MD, & Diana Girnita, MD, PhD  |  April 15, 2022

Sarcoidosis is a multisystem disease characterized by noncaseating granulomas in affected tissues, mostly involving the lungs and lymph nodes.1,2 The etiology of sarcoidosis remains unknown but is thought to be due to an inflammatory response to an antigen exposure in genetically predisposed individuals.1 Tumor necrosis factor-α (TNF‑α), a pro-inflammatory cytokine, plays an essential role in…

This image from the MRI demonstrates suprapatellar bursal fluid of mixed signal.

Case Report: Persistent Knee Warmth Mimics Juvenile Idiopathic Arthritis

Eman Bamashmous, MBBS, Buthaina Al Adba, MBBS, CABP, & Sharon Bout-Tabaku, MD, MSCE  |  March 14, 2022

Intra-articular venous malformations of the knee are an uncommon cause of knee pain in children. Presenting symptoms of this rare subtype of venous malformation often include nonspecific pain and joint swelling, which may be episodic, and accompanied by limited range of motion. The signs and symptoms can mimic juvenile idiopathic arthritis (JIA). Timely diagnosis of…

‘Nothing but NET[osis]’: RheumMadness 2022 Anti-NET Antibodies Scouting Report

The UNC Rheumatology Fellowship Program: Leah Bettner, MD; Shruti Chandramouli, MD; Christopher Overton, MD; Astia Allenzara, MD; Michael Cunningham, MD; & Luis Palomino, MD  |  February 8, 2022

Neutrophil extracellular traps (NETs) contribute to the pathogenesis of multiple autoimmune diseases. And research has shown that patients with antiphospholipid syndrome (APS) have higher levels of circulating anti-NET antibodies than healthy controls, indicating a potential biomarker.

Update on Extrapulmonary Sarcoidosis

Lara C. Pullen, PhD  |  December 6, 2021

Neurosarcoidosis & sarcoid dermatopathology are discussed.

From Strength to Strength: Idiopathic Inflammatory Myopathy Diagnosis & Management

Jason Liebowitz, MD, FACR  |  December 2, 2021

During the ACR Convergence 2021 Review Course, Rohit Aggarwal, MD, MS, provided an update on idiopathic inflammatory myopathy.

Experts Discuss Blood Disorders Commonly Seen in Lupus Patients

Samantha C. Shapiro, MD  |  December 2, 2021

ACR CONVERGENCE 2021—Hematologic abnormalities are common in systemic lupus erythematosus (SLE), whether due to SLE itself or something else. As rheumatology professionals, we are routinely challenged by the management of cytopenias in our SLE patients. At the ACR’s annual meeting in 2021, two hematologists shared expert advice regarding common hematologic manifestations of SLE. Michael B….

New Video Shows How to Perform a Lip Biopsy to Diagnose Sjögren’s Syndrome

Susan Bernstein  |  November 14, 2021

Labial salivary gland biopsy (i.e., lip biopsy) is a useful tool to help diagnose Sjögren’s syndrome in suspected patients, but most rheumatologists are not trained to perform the minimally invasive procedure. A new, 40-minute training video and slide presentation with step-by-step instructions may help them fill that critical skill gap. Two rheumatologists collaborated to create…

Basic Science: New Insights into Inflammation in OA, VEXAS, COVID-19 & More

Samantha C. Shapiro, MD  |  November 10, 2021

Michael B. Brenner, MD, addresses exciting advances in basic science in rheumatology, including insights into inflammation in osteoarthritis, the adult-onset autoinflammatory syndrome VEXAS and more.

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