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Research Rheum

New ACR Open Rheumatology Journal Delivers Science to Wide Audience

Susan Bernstein  |  September 17, 2019

The ACR’s newest journal, ACR Open Rheumatology (ACROR), launched in 2019 with all articles published in full online. The journal publishes high-quality, rigorously peer-reviewed articles on original investigations in rheumatology research, including basic science, clinical science, epidemiology, health outcomes and education, as well as commentaries and reviews. Open access is on the rise. A 2017…

Long-Term Physical Activity Lowers the Risk of RA among Women

Arthritis & Rheumatology  |  August 27, 2019

A new study adds to the evidence that metabolic factors play an important role in the pathogenesis of rheumatoid arthritis (RA). In this large, prospective cohort study, Liu et al. found that increased physical activity among women was associated with a reduced risk of RA…

The Choose Rheumatology Experience Encourages Med Students, Residents to Pursue Rheumatology Careers

From the College  |  August 16, 2019

Medical students and residents are choosing careers in rheumatology, thanks in part to the annual Choose Rheumatology Experience hosted by the Rheumatology Research Foundation during the ACR/ARP Annual Meeting. The Choose Rheumatology Experience is a special half-day program designed to help future physicians and rheumatology professionals navigate the Annual Meeting. Cultivating interest in rheumatology is…

In Mouse Model, a TLR-9 Deficiency May Trigger Severe Lupus

Kurt Ullman  |  August 16, 2019

Toll-like receptors play an important role in host defense. TLR-7 recognizes viral ssRNA, but also plays a role in the development of systemic lupus erythematosus (SLE). Genetic ablation of a similar receptor, TLR-9, results in opposite effects, with severe disease and kidney involvement. The mechanism of how this works remains unknown. Anna-Marie Fairhurst, PhD, from…

Study Probes Whether Belimumab Can Lower Vasculitis Relapse Rate

Catherine Kolonko  |  August 16, 2019

In an international clinical trial, adding the drug belimumab to standard maintenance therapy for patients in remission with vasculitis did not lower the relapse rate. The double-blind, placebo-controlled study evaluated the safety and efficacy of belimumab as adjunctive therapy to maintain remission in anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). Results of the multi-center, industry-sponsored…

New Studies Identify Possible Markers of Early Systemic Sclerosis

Bryn Nelson, PhD  |  August 16, 2019

Although the true cause of systemic sclerosis (SSc), or scleroderma, remains unknown, researchers have made progress in detecting the autoimmune disease’s early presence. Beyond the physiological signs of Raynaud’s phenomenon, a capillaroscopy can detect alterations in microcirculation and lab tests can confirm the presence of telltale autoantibodies, such as anti-topoisomerase 1, anti-centromere and anti-RNA polymerase…

Asthma, Allergic Disease, Passive Smoke Exposure & the Risk of RA

Arthritis & Rheumatology  |  August 7, 2019

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. One hypothesis is that inflammation in the respiratory tract results in autoantibody formation that later leads to disease. Kronzer et al. set out to narrow the knowledge gaps related to the oral-respiratory factors that may mediate RA pathogenesis.

A More Complicated Pregnancy: Inflammatory Arthritis Increases the Risk for Adverse Outcomes

Arthritis Care & Research  |  August 2, 2019

Pregnant women with inflammatory arthritis may have an increased risk for preterm delivery. New research examined the risk of preterm delivery and other pregnancy complications in women with RA and JIA vs. healthy controls…

Practical, Diverse Knowledge: A Preview of 2019’s ARP Sessions

From the College  |  July 26, 2019

From insights into mentoring and statistics to integrating virtual reality into a patient’s rehab—the educational sessions offered during the ACR/ARP Annual Meeting will be practical, yet innovative and inspiring…

The Rheumatology Research Foundation Announces Award Recipients

From the College  |  July 18, 2019

On July 1, 2019, the Foundation awarded more than 80 grants to a wide range of rheumatology trainees, professionals and institutions. The recipients will receive funding for essential training and career development, as well as for innovative research projects. Their applications were closely examined by experts in different areas of the field to ensure awards…

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