Treatment for RA should involve targeting subclinical disease and reversing immune dysregulation, expert says
Researchers Explore HLA-B27’s Role in the Development of Spondylitis
New research reports on the increased sensitivity of human-HLA-B27 transgenic rat bone marrow monocytes to TNF-α stimulation and osteoclast differentiation. (posted June 27, 2013)
Can Lubricating Joints Prevent Osteoarthritis?
Proteoglycan 4 (Prg4), also known as lubricin, could slow the process of cartilage destruction in osteoarthritis. (posted June 13, 2013)
Small Fiber Function May Be Linked to Fibromyalgia
Researchers show, for the first time, that small fiber function and morphology is impaired in patients with fibromyalgia. (posted June 18, 2013)
Th17 May Contribute to Bone Destruction by Modifying Osteoclasts
New research describes the role of RANKL-expressing Th17 cells in inflammatory bone destruction. (posted June 3, 2013)
Advances in Genomics, Bioinformatics Draw New Insights From the Human Genome
Widely held belief that large segments of the human genome consist of ‘junk DNA’ is incorrect, say scientists
Arthritis Care & Research Celebrates 25 Years
From its beginnings as a quarterly journal in 1988, to a successful monthly publication today, AC&R has evolved and thrived
Salt as a Promoter of Th17 Cells and Autoimmune Disease
New research on Th17 suggests that a high salt diet may be a risk factor for inflammation.
Steroid Injections for Lateral Epicondylalgia Worse than Placebo in Long Term
In a recent study of unilateral lateral epicondylalgia, corticosteroid injection resulted in worse clinical outcomes compared to placebo injection, and there were no significant differences in those who received physical therapy or no physical therapy.
Chondrocyte Enlargement Sheds New Light on Cell Volume Regulation
New research describes the regulation of skeletal size and explores how cells sense, modify, and establish a volume set point.
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