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Search results for: Biologics

How to Treat Refractory Polymyalgia Rheumatica

Katie Robinson  |  January 25, 2024

Patients with polymyalgia rheumatica (PMR) who had relapsed while tapering glucocorticoid therapy were more likely to achieve sustained remission at one year and have a lower glucocorticoid exposure if they were treated with sarilumab (Kevzara) plus a rapid, 14-week glucocorticoid taper than if they received placebo plus a standard, 52-week glucocorticoid taper. This is according…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOther Rheumatic ConditionsResearch Rheum Tagged with:glucocorticoid resistantIL-6IL-6 inhibitorsPMR FocusRheumPolymyalgia RheumaticaResearch Reviewsarilumab

The 2023 ARP Merit Awards

Patrice Fusillo  |  January 10, 2024

SAN DIEGO—During ACR Convergence 2023 in November, the ACR and the ARP honored a group of distinguished individuals who have made significant contributions to rheumatology research, education and patient care. This month, The Rheumatologist profiles the recipients of the ARP Merit Awards and ARP Master class, recognizing outstanding contributions to the field of rheumatology. The…

Filed under:ACR ConvergenceAwardsCareerMeeting Reports Tagged with:ACR Convergence 2023Association of Rheumatology Professionals (ARP)

An Interview with Expert Clinician Dr. Fred Wigley

Jason Liebowitz, MD, FACR  |  January 10, 2024

Rheumatologists who are outstanding researchers, educators and/or clinicians, who provide consistently exceptional care to patients, who have achieved a level of  distinction in the field and who serve as role models for colleagues and trainees are highlighted in this recurring series. Fred Wigley, MD, MACR, is the Martha McCrory Professor of Medicine at the Johns…

Filed under:OpinionProfiles Tagged with:Dr. Fred WigleyRole Models in Rheumatology

Pharmacokinetic Modeling & Efficacy Extrapolation: FDA Takes New Approaches to Drug Approvals

Thomas R. Collins  |  January 4, 2024

An array of new and expanded indications of therapeutics for rheumatic disease last year relied on pharmacokinetic modeling for intravenous dosing and efficacy extrapolation for pediatric populations.

Filed under:ACR ConvergenceAxial SpondyloarthritisBiologics/DMARDsConditionsDrug UpdatesMeeting ReportsPediatric ConditionsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2023ApprovalsBiosimilarsU.S. Food and Drug Administration (FDA)

Insight into the FDA Approval of Ustekinumab Biosimilar

Michele B. Kaufman, PharmD, BCGP  |  December 14, 2023

In late October, the FDA approved the first biosimilar to ustekinumab to treat patients with psoriasis, psoriatic arthritis and other conditions. Ustekinumab-auub is expected to be available in the U.S. by 2025.

Filed under:Biologics/DMARDsConditionsDrug UpdatesPsoriatic Arthritis Tagged with:FDA approvalU.S. Food and Drug Administration (FDA)ustekinumab

The Great Debate 2023

Ruth Jessen Hickman, MD  |  December 4, 2023

SAN DIEGO—Panelists at ACR Convergence 2023 debate the merits of IL-6 inhibitors vs. glucocorticoids for the initial treatment of giant cell arteritis (GCA) and polymyalgia rheumatica (PMR).

Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic ConditionsVasculitis Tagged with:ACR Convergence 2023PMR FocusRheumPolymyalgia Rheumatica

ACR Advocacy Staff Outline Victories, Challenges from a Busy Year

Thomas R. Collins  |  November 21, 2023

SAN DIEGO—In an advocacy update session at ACR Convergence 2023, ACR staff described progress in multiple priority areas, including access to care and workforce issues.

Filed under:ACR ConvergenceLegislation & Advocacy Tagged with:ACR advocacyACR Convergence 2023

The Heterogeneity of Psoriatic Arthritis

David S. Pisetsky, MD, PhD  |  November 21, 2023

SAN DIEGO—Differences between psoriatic arthritis and rheumatoid arthritis highlight the need for the development of imaging modalities, laboratory tests and other biomarkers that are explored and validated specifically for PsA to advance the goal of personalized or precision medicine. In this article, expert David S. Pisetsky, MD, PhD, explores the top research in psoriatic arthritis presented at ACR Convergence 2023.

Filed under:ACR ConvergenceConditionsMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2023ACR Convergence 2023 PsAPsA Resource Center

Non-Radiographic Axial Spondyloarthritis: A Review

Jason Liebowitz, MD, FACR  |  November 16, 2023

SAN DIEGO—Alexis Ogdie-Beatty, MD, MSCE, associate professor of medicine, associate professor of epidemiology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, gave a presentation on non-radiographic axial spondyloarthritis (nr-axSpA) in the Review Course prior to ACR Convergence 2023.

Filed under:ACR ConvergenceAxial SpondyloarthritisConditionsMeeting Reports Tagged with:ACR Convergence 2023AS Resource Center

Growing Up

Jason Liebowitz, MD, FACR  |  November 14, 2023

SAN DIEGO—In the pre-ACR Convergence 2023 Review Course, Rebecca Sadun, MD, PhD, assistant professor in medicine and pediatrics, Duke University School of Medicine, Durham, N.C., focused on transitions from pediatric to adult rheumatology care for patients with juvenile idiopathic arthritis (JIA).

Filed under:ACR ConvergenceConditionsMeeting ReportsPediatric Conditions Tagged with:ACR Convergence 2023JIAsJIAUveitis

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