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Search results for: Biologics

ACR Commends CMS Decision to Withdraw Most Favored Nation Payment Model for Part B Drugs

From the College  |  August 11, 2021

ATLANTA—The American College of Rheumatology (ACR) today applauded the U.S. Centers for Medicare & Medicaid Services’ (CMS) decision to withdraw a proposed rule to implement the “Most Favored Nation” (MFN) payment model for Part B drugs. Leaders felt the policy would have dramatically disrupted patient access to critical therapies needed to manage rheumatic diseases and…

Filed under:Drug UpdatesLegislation & Advocacy Tagged with:American College of Rheumatology (ACR)Centers for Medicare & Medicaid Services (CMS)Medicare Part BMedicare Part B drugsMost Favored Nation

Therapeutic Drug Monitoring May Offer Little Benefit to Patient Remission Rates During Infliximab Induction Therapy

Lara C. Pullen, PhD  |  August 9, 2021

Although rheumatologists prescribe tumor necrosis factor inhibitors (TNFi’s) to treat several rheumatic diseases, they recognize immunogenicity influences the efficacy and safety of TNFi’s. Example: The formation of anti-drug antibodies can affect infusion reactions and cause low-serum drug levels and therapeutic failure. The induction phase is a period of high incidence of immunogenicity, and observational data…

Filed under:Drug Updates Tagged with:infliximabtherapeutic drug monitoringTNF inhibitorTNFitumor necrosis factor inhibitor (TNFi)

Manifestations of JIA: JIA-Associated Uveitis, sJIA & Lung Involvement in sJIA

Jason Liebowitz, MD, FACR  |  July 16, 2021

JIA can manifest in a variety of ways. Experts discuss the implications of uveitis, systemic disease and lung involvement in sJIA.

Filed under:ConditionsMeeting Reports Tagged with:eyesJIA-associated uveitisjuvenile idiopathic arthritis (JIA)lungsPediatric RheumatologyPediatric Rheumatology SymposiumPRSYMsJIAsJIA-associated lung disease

Early & Long-Term Remission of Spondyloarthritis

Jason Liebowitz, MD, FACR  |  July 16, 2021

Filip Van den Bosch, MD, described his strategies for caring for patients with SpA and the possibility of achieving disease inactivity.

Filed under:Axial SpondyloarthritisConditionsEULAR/OtherMeeting Reports Tagged with:EULARpatient carespondyloarthritis

High Cost of Specialty Drugs Demands Action

Mary Beth Nierengarten  |  July 6, 2021

Amid rising drug costs and the growing influence of pharmacy benefit managers on patient care decisions, physicians are increasingly called upon to advocate for affordable, evidence-based treatments for their patients.

Filed under:Legislation & AdvocacyPractice Support Tagged with:drug pricingpharmacy benefit managers (PBMs)

Higher Risk of Adverse Events When Biologic Infusions Are Done at Home

By Lisa Rapaport  |  June 15, 2021

(Reuters Health)—Patients who receive biologic infusions at home may have a higher risk of adverse events than those who receive the infusions at a health care facility, a new study suggests.1 Researchers examined administrative claims data on 57,220 adults who received a total of 752,150 biologic infusions for immune-mediated disease between 2007 and 2017. The…

Filed under:Biologics/DMARDsDrug Updates Tagged with:biologic infusionsBiologicshome infusion

A Unified Advocacy Voice for Rheumatology

David R. Karp, MD, PhD, & Christine Stamatos, DNP, ANP-C  |  June 13, 2021

One thing that became clear very quickly this past year was that the COVID-19 pandemic would change the way we deliver care to patients. What has not changed amid an evolving healthcare landscape is our driving focus to ensure our patients’ access to rheumatology care and the availability of state-of-the-art treatments. We know you share…

Filed under:Legislation & AdvocacyPresident's Perspective Tagged with:COVID-19RheumPACSafe Step Act

Gut Feeling: A Comprehensive Look at the Pathogenesis, Management & Treatment of Inflammatory Bowel Disease

Jason Liebowitz, MD, FACR  |  May 24, 2021

Patients with autoimmune diseases, such as spondyloarthritis, are at risk of developing inflammatory bowel disease. Here are considerations for its management and treatment.

Filed under:ConditionsMeeting Reports Tagged with:ACR State-of-the-Art Clinical SymposiumIBDinflammatory bowel disease (IBD)

The Race Is On: Clinical Trials Begin for Agents Biosimilar to Denosumab

Michele B. Kaufman, PharmD, BCGP  |  May 24, 2021

As the U.S. and other patents for branded denosumab products get closer to expiring, drug manufacturers are initiating clinical trials for more affordable, biosimilar versions of the treatment.

Filed under:Biologics/DMARDsDrug Updates Tagged with:BiosimilarsdenosumabEB1001monoclonal antibody

A 2021 Update on Lupus Management & Treatment

Jason Liebowitz, MD, FACR  |  May 13, 2021

At the 2021 ACR State-of-the-Art Clinical Symposium, Saira Sheikh, MD, associate pro­fessor of Medicine and director of the Rheumatology Lupus Clinic, University of North Carolina, Chapel Hill, provided an update on the past, present and future of the management of systemic lupus erythematosus (SLE). This year, hydroxychloroquine received a great deal of attention, given early…

Filed under:ConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:2021 State of the Art Clinical SymposiumbelimumabHydroxychloroquine (HCQ)voclosporin

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