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Search results for: Primary care

ACR’s New AS & Nonradiographic Axial SpA Treatment Recommendations

American College of Rheumatology  |  September 24, 2015

ATLANTA—The American College of Rheumatology (ACR) has released new recommendations for the treatment of ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (SpA). The guideline was developed with the Spondylitis Association of America (SAA) and the Spondyloarthritis Research and Treatment Network. It summarizes recommendations for both pharmacologic and non-pharmacologic treatments, including rehabilitation, management of patients with…

Filed under:Axial SpondyloarthritisConditionsFrom the College

EULAR 2015: Benefits of Individualizing Exercise Therapy

Rikke Helene Moe, PT, MSc, PhD  |  September 15, 2015

ROME, Italy—The medical environment is increasingly adapting to the possibilities of optimizing care by individualizing medical treatment and tailoring treatment to disease phenotypes. Data suggest that individualizing exercise therapy, an important treatment modality for rheumatic and musculoskeletal diseases, can help control disease, maximize function, minimize functional barriers and decrease the risk of co-morbidity.1,2,3 Personalizing exercise…

Filed under:ConditionsMeeting ReportsRheumatoid Arthritis Tagged with:exercise therapypatient careRArheumatic and musculoskeletal disease phenotypesRheumatoid arthritisRMDTreatment

Diagnosing, Treating IgG4-Related Disease

Mary Beth Nierengarten  |  September 15, 2015

In diagnosing and treating a disease that is rapidly gaining recognition worldwide since it was first recognized in Japan in 2003, 42 experts from 10 different countries recently collaborated to discuss and review the current experience and data on IgG4-related disease. The result is the “International Consensus Guidance Statement on the Management and Treatment of…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:ClinicalDiagnosisIgG4 related diseaseoutcomepatient careTreatment

ACR Releases Two New Publications

American College of Rheumatology  |  September 15, 2015

Two new ACR publications, created in collaboration with the European League Against Rheumatism, aim to improve the treatment of patients with polymyalgia rheumatica (PMR) and introduce new classification criteria for gout…

Filed under:ConditionsFrom the CollegeGout and Crystalline Arthritis Tagged with:American College of Rheumatology (ACR)European League Against RheumatismGoutPolymyalgia Rheumatica

Epratuzumab Results Disappointing, but Adalimumab Promising

Michele B. Kaufman, PharmD, BCGP  |  August 19, 2015

Two Phase 3 trials have shown that epratuzumab did not meet its primary endpoints for treating SLE. Meanwhile, a Phase 3 study has shown adalimumab is effective for treating enthesitis-related arthritis in juveniles…

Filed under:Biologics/DMARDsDrug Updates Tagged with:adalimumabenthesitis-related arthritisepratuzumabJuvenile arthritissystemic lupus erythematosus (SLE)

Biosimilar Drugs for RA Studied in Multiple Trials

Michele B. Kaufman, PharmD, BCGP  |  August 17, 2015

Etanercept Biosimilars A number of Phase 3 trials are ongoing for etanercept biosimilars.1 One evaluation identified three trials in rheumatoid arthritis (RA) patients and one in psoriasis patients. The psoriatic arthritis trial evaluated PASI as a primary endpoint and the following secondary endpoints: PASI50, PASI75, PASI90, PASI score, laboratory values, ECG, adverse events (AEs), injection…

Filed under:Biologics/DMARDsConditionsDrug UpdatesRheumatoid Arthritis Tagged with:Biosimilarsclinical trialsDrugsoutcomeRheumatoid arthritisrheumatologySafety

EULAR 2015: Biology of Fatigue Rooted in Genes, Cytokines, Free Radicals

Thomas R. Collins  |  August 17, 2015

ROME, Italy—Fatigue, a problem experienced frequently by patients with rheumatic diseases, is best thought of as a survival mechanism and as a single phenomenon, not a condition that comes in a variety of forms, an expert said in a session at EULAR 2015, the annual congress of the European League Against Rheumatism (EULAR). Gene Regulated…

Filed under:ConditionsEULAR/OtherMeeting ReportsResearch Rheum Tagged with:CytokinesEULARfatiguegeneResearchRheumatic Disease

Catastrophic Antiphospholipid Syndrome with Pulmonary Hemorrhage: A Case Report

Joy-Ann Tabanor, MD, Hyun Bae, MD, Girish Sonpal, MD, & Karlene Williams, MD  |  August 17, 2015

Antiphospholipid syndrome (APS) is an autoimmune condition characterized by hypercoagulability often manifested as recurrent thrombosis or pregnancy complications, with persistently circulating antiphospholipid (aPL) antibodies or lupus anticoagulant. Catastrophic APS (CAPS), also known as Asherson syndrome, occurs in less than 1% of cases of APS and involves occlusive microangiopathy in at least three organ systems.1 Case…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:Antiphospholipid Antibody Syndrome (APS)catastrophic antiphospholipid syndromeClinicalDiagnosishemorrhageHughes Syndromeoutcomepatient carePulmonary

Precision Medicine in Rheumatology May Improve Diagnosis, Disease Classification

Richard Quinn  |  August 7, 2015

In an interview with The Rheumatologist, J. Larry Jameson, MD, PhD, discusses the benefits and complications of precision medicine for rheumatologists and their patients, including advances in genetics, diagnostic tools and targeted treatments…

Filed under:Practice Support Tagged with:Personalized medicinePractice ManagementPrecision Medicinerheumatology

Phase 3 Studies Evaluate Lesinurad for Gout Treatment

Michele B. Kaufman, PharmD, BCGP  |  July 15, 2015

For 12 months, two studies examined the use of lesinurad in combination with allopurinol to treat gout, with patients achieving reduced serum uric acid levels and demonstrating no severe toxicity.

Filed under:ConditionsDrug UpdatesEULAR/OtherGout and Crystalline ArthritisMeeting Reports Tagged with:AllopurinolEULARGoutlesinurad

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