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Search results for: axial spondyloarthritis

Early & Long-Term Remission of Spondyloarthritis

Jason Liebowitz, MD, FACR  |  July 16, 2021

Filip Van den Bosch, MD, described his strategies for caring for patients with SpA and the possibility of achieving disease inactivity.

Filed under:Axial SpondyloarthritisConditionsEULAR/OtherMeeting Reports Tagged with:EULARpatient carespondyloarthritis

Cytokine Targets & Treatment Developments for Psoriatic Arthritis & Spondyloarthritis

Carina Stanton  |  March 15, 2021

ACR CONVERGENCE 2020—In recent years, a pathophysiological role for the interleukin (IL) 17/IL-23 axis in the development of psoriasis, enthesitis and inflammatory arthritis has been investigated in both rodent and human models. Clinical trials have demonstrated differential benefits for skin disease and joint disease in patients with psoriatic arthritis, axial spondyloarthritis (axSpA) and ankylosing spondylitis…

Filed under:Axial SpondyloarthritisConditionsPsoriatic Arthritis Tagged with:ACR Convergence 2020Ankylosing SpondylitisIL-17/IL-23 CytokineJanus Kinase InhibitorsPsoriatic Arthritis

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Men, Women & Medical Differences in Axial Spondyloarthropathy

Ruth Jessen Hickman, MD  |  October 24, 2019

Historically, ankylosing spondylitis was considered mainly a male disease. But it has become evident this predominance is not as great as previously believed. Here we discuss recent developments in the area, including potential differences between the sexes in symptom and disease burden, immunological and genetic background, diagnostic delay, treatment response and ongoing research questions. Medical…

Filed under:Axial SpondyloarthritisConditions Tagged with:Ankylosing Spondylitisaxial spondyloarthritis (SpA)Gendersexual dimorphism

Peripheral Arthritis & Recent Onset Axial SpA: 5-Year Results from the DESIR Cohort

Lara C. Pullen, PhD  |  July 29, 2019

An analysis of follow-up data from the DESIR cohort showed patients with recent onset axial spondyloarthritis who experienced peripheral arthritis had worse symptoms and quality of life long term. In the study, peripheral arthritis was also associated with negative HLAB27, non-smoking and the presence of other peripheral disease manifestations…

Filed under:Axial SpondyloarthritisConditions Tagged with:axial spondyloarthritis (SpA)peripheral arthritis

Peripheral Manifestations of Spondyloarthritis

Lara C. Pullen, PhD  |  May 29, 2019

A recent study evaluated the factors associated with the presence of peripheral manifestations of spondyloarthritis (SpA), which affects more than half of patients with SpA. Researchers found that being older, HLAB27 negative and having a history of psoriasis were associated with these symptoms…

Filed under:Axial SpondyloarthritisConditions Tagged with:peripheral arthritisperipheral spondyloarthritis

Ixekizumab Promising for Non-Radiographic Axial SpA; Plus FDA Approves Belimumab for Pediatric Lupus

Michele B. Kaufman, PharmD, BCGP  |  May 21, 2019

Results from a Phase 3 study showed ixekizumab significantly improved the signs and symptoms of non-radiographic axial spondyloarthritis in patients…

Filed under:Biologics/DMARDsDrug Updates Tagged with:belimumabFDAixekizumabnon-radiographic axial spondyloarthritissystemic lupus erythematosus (SLE)U.S. Food and Drug Administration (FDA)

FDA Approves Certolizumab Pegol for Treating Non-Radiographic Axial SpA

Michele B. Kaufman, PharmD, BCGP  |  April 30, 2019

Certolizumab pegol is now FDA approved to treat adults with active non-radiographic axial spondyloarthritis…

Filed under:Drug Updates Tagged with:axial spondyloarthritis (SpA)Certolizumab PegolFDAnon-radiographic axial spondyloarthritisU.S. Food and Drug Administration (FDA)

Can Peripheral Spondyloarthritis Be Reversed?

Ruth Jessen Hickman, MD  |  November 18, 2018

Currently, treatment options for patients with peripheral spondyloarthritis, which includes psoriatic arthritis and non-psoriatic types, are limited. Philippe Carron, MD, Department of Rheumatology, Ghent University Hospital, Belgium, says, “One of the problems we encounter in the daily management of peripheral spondyloarthritis is that we have no other therapeutic options in patients refractory to NSAIDs [non-steroidal…

Filed under:Axial SpondyloarthritisConditionsResearch Rheum Tagged with:TNF inhibitors

Bone Marrow Edema Studied for Spondyloarthritis Diagnostic Insights

Catherine Kolonko  |  August 17, 2018

Researchers in Demark studied joints of young adult athletes to better understand the difference in bone marrow edema common in healthy people vs. what is experienced by patients with spondylo­arthritis, a serious inflammatory condition of the spine and sacroiliac joints. Early recognition of spondylo-arthritis can be tricky because it can be confused with symptoms and…

Filed under:Axial SpondyloarthritisConditions Tagged with:bone marrow edema (BME)Magnetic resonance imaging (MRI)

2017 Update of Treat-to-Target Recommendations for Axial & Peripheral SpA & PsA

Michele B. Kaufman, PharmD, BCGP  |  August 7, 2017

An international task force has updated recommendations for axial and peripheral spondyloarthritis, and psoriatic arthritis, which include treat-to-target recommendations…

Filed under:Axial SpondyloarthritisConditions Tagged with:axial spondyloarthritis (SpA)Guidelinesperipheral spondyloarthritisrecommendationstarget

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