BOSTON (Reuters)—A Rhode Island doctor pleaded guilty on Wednesday to charges he participated in a scheme to obtain kickbacks in exchange for writing prescriptions for an addictive fentanyl-based cancer pain drug produced by Insys Therapeutics Inc. The plea by Jerrold Rosenberg came amid ongoing investigations of Insys related to Subsys, an under-the-tongue spray that contains…
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Rheumatology Health Professionals
‘Living’ Pelvis in the Guinness Book of World Records Shashank Akerkar, MD, an ACR fellow and rheumatoid arthritis specialist at the Mumbai Arthritis Clinic and Research Center in India, found a unique way to draw attention to ankylosing spondylitis (AS). He persuaded 425 patients, mostly those suffering from AS or affected by lupus or rheumatoid…

The ACR Pre-Meeting Research Conferences to Explore Immunity, Precision Medicine in Rheumatic Diseases
Connect with colleagues at the Basic Research Conference (BRC) and the Clinical Research Conference (CRC) pre-meeting courses at the 2017 ACR/ARHP Annual Meeting! The ACR has an exceptional array of research leaders lined up for this year’s BRC and CRC courses on Friday, Nov. 3, and Saturday, Nov. 4, in San Diego. Get ready to…

Autoreactive Germinal Centers: A Single Autoreactive B Cell Clone Can Drive Autoimmunity
A study in mice provides insight into the maturation of the self-reactive B cell response, contextualizing the epitope spreading observed in autoimmune disease. Researchers found that clonal expansion of wild type B cells in autoreactive germinal centers appeared to be at the heart of epitope spreading and the consequent autoimmune response…
New Jersey Sues Insys as Opioid Maker Settles with Massachusetts
BOSTON (Reuters)—New Jersey on Thursday accused Insys Therapeutics Inc of engaging in a fraudulent scheme to boost sales of a fentanyl-based cancer pain drug, as Massachusetts announced a $500,000 settlement with the drugmaker to resolve similar allegations. The lawsuit by New Jersey Attorney General Christopher Porrino accused Insys of illegally directing its sales force to…
Cigna to End OxyContin Painkiller Coverage, Signs Contract for Alternative
(Reuters)—Amid a growing U.S. opioid addiction, health insurer Cigna Corp will stop covering OxyContin, the opioid painkiller sold by Purdue Pharma LP, as of January 1 and will instead cover an equivalent with a formulation less vulnerable to abuse, the company said on Wednesday. The insurer has signed a “value-based contract” with Collegium Pharmaceutical Inc…

Efficacy Studied Following Accelerated Drug Approvals
In recent years, the number of drugs to receive accelerated FDA approval has increased. A new study examined whether these drugs have demonstrated efficacy in post-approval trials…
From the Front Lines: Managing RA Comorbidities in Primary Care
How are comorbidities for RA patients managed outside of rheumatology? A recent Canadian study developed and assessed quality measures related to preventive care and screenings for RA patients in a primary care setting, comparing RA and non-RA patients. The results: Primary care physicians often provide similar levels of care to patients with and without RA. But RA patients were less likely to receive some cancer screenings and all necessary tests to assess their cardiovascular risk…
Republican Bill to Repeal Obamacare Teeters on Edge of Collapse
WASHINGTON (Reuters)—The latest Republican effort to repeal former U.S. President Barack Obama’s signature healthcare law faced possible defeat this week as several senators in the party voiced concerns about the bill under consideration. The U.S. Senate is up against a Saturday deadline for deciding the fate of the 2010 Affordable Care Act, popularly known as…
Many Drug Companies Fail to Conduct Timely Safety Checks on Medicines after FDA Approval
(Reuters Health)—In the rush to approve new medicines, the U.S. Food and Drug Administration often requires drug companies to study possible side effects and alternative doses for medicines once they hit the broader market. A September 20 online analysis in the New England Journal of Medicine concludes that, in many cases, that’s not being done….
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