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Search results for: fever

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Yao Syndrome: A Case Report & Clinical Review

Peter Gorevic, MD, & Qingping Yao, MD, PhD  |  November 12, 2020

Case Presentation History of present illness A 66-year-old white woman presented with unexplained, recurrent episodes of high fever, abdominal pain, rash and arthralgias occurring over the previous three years. During typical episodes, the patient experienced flu-like symptoms, followed by fever, abdominal pain and non-bloody diarrhea without tenesmus. Her temperatures were 101–103ºF, with chills lasting up…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:case reportNOD2-associated auto­inflammatory diseaseYao Syndrome

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A Look Back at Pirquet & Schick’s Influential Serum Sickness Study

Ruth Jessen Hickman, MD  |  November 12, 2020

In 1905, two pediatricians in Vienna, Austria, published Serum Sickness, a detailed 120-page monograph that was the first to carefully characterize the syndrome.1 The work would go on to become a classic, ultimately helping illuminate many important questions in immunology. Antitoxin Serum Treatments In the late 19th century, researchers were working to develop lifesaving antitoxins…

Filed under:Conditions Tagged with:Lost & FoundSerum Sickness

Dr. Fauci Talks COVID-19 with the ACR

Susan Bernstein  |  November 10, 2020

ACR CONVERGENCE 2020—At the ACR’s fully virtual annual meeting on Saturday, Nov. 7, Anthony S. Fauci, MD, director of the National Institute of Allergy and Infectious Diseases (NIAID) since 1984, delivered a special lecture on COVID-19, from virology to therapy to vaccine development. Novel Coronavirus, Familiar Vectors When Chinese physicians first reported infections by what…

Filed under:ACR ConvergenceMeeting Reports Tagged with:ACR Convergence 2020Anthony S. FauciCOVID-19

ACR Convergence 2020: COVID-19 Hyper-Inflammation in Kids

Jason Liebowitz, MD, FACR  |  November 9, 2020

ACR CONVERGENCE 2020—Among the many ways in which the COVID-19 pandemic has changed the face of modern medicine is the emergence of multisystem inflammatory syndrome in children (MIS-C), a rare but serious condition that shares many features of Kawasaki disease (KD). With this topic in mind, leading pediatric experts from around the world came together…

Filed under:ACR ConvergenceConditionsMeeting ReportsPediatric Conditions Tagged with:ACR Convergence 2020COVID-19Multisystem Inflammatory Syndrome in Children (MIS-C)

Adapting Care During COVID-19: Q&A with Brett Smith, DO

Mary Choy, PharmD, BCGP, FASHP  |  November 9, 2020

The COVID-19 global pandemic has disrupted rheumatology clinics and practices all over the world. In the U.S., many providers have used telemedicine to expand access to care for their patients while managing in-person visits. Brett Smith, DO, who practices at the Blount Memorial Physicians Group, East Tennessee Children’s Hospital, Knoxville, spoke with The Rheumatologist about…

Filed under:Practice SupportProfessional Topics Tagged with:COVID-19patient carePractice Management

Case Report: A 40-Year-Old Man with Vasculitic Neuropathy

Case Report: A 40-Year-Old Man with Vasculitic Neuropathy

Martin Garber, DO, & David Fivenson, MD  |  October 19, 2020

Ironically, chronic exposure to minocycline has also been associated with a variety of autoimmune syndromes, including drug-induced lupus, auto­immune hepatitis, serum sickness and vasculitis.1 Minocycline is associated with an 8.5-fold increased risk of drug-induced lupus.2 Minocycline and nitrofurantoin are implicated in 90% of cases of drug-induced autoimmune hepatitis.3 Minocycline-induced vasculitis is much less common and,…

Filed under:ConditionsVasculitis Tagged with:minocyclinepolyarteritis nodosavasculitic neuropathy

Case Report: A COVID-19 Mimic

Andrea Ramirez-Gomez, MD, & Katherine Kougias Temprano, MD  |  September 11, 2020

A 67–year-old white woman with primary Raynaud’s phenomenon presented following a week of progressively worsening shortness of breath, dry cough and generalized malaise. An avid tennis player, she first noticed dyspnea while playing, but a few days later grew short of breath even at rest. She went to an urgent care center, where a computed…

Filed under:ConditionsVasculitis Tagged with:COVID-19granulomatosis with polyangiitisRaynaud’s phenomenon

Study Provides Clues to Undefined, Systemic, Autoinflammatory Diseases

Kurt Ullman  |  September 1, 2020

A study from October 2019 describes the clinical characteristics of pediatric patients with undefined systemic autoinflammatory diseases. Researchers conducted a genetic analysis and outlined specific variants. They found patients with pericarditis and intellectual impairment may have distinct clinical phenotypes, which may lead to improved diagnostic and treatment options.

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:geneticPediatricsystemic autoinflammatory diseases

How to Create a Safe Practice & Prep for a COVID-19 Resurgence

Steven M. Harris, Esq.  |  August 12, 2020

For many months, the healthcare world has been significantly affected by the swift and per­vasive effects of SARS-CoV-2, which causes COVID-19. The virus has severely affected the delivery of patient care by all providers, including those in hospitals and emergency care settings, who grappled with the response to massive influxes of COVID-19 patients, and those…

Filed under:Legal UpdatesPractice Support Tagged with:COVID-19personal protective equipment (PPE)Safety

Figure 1A–C: Arrows denote hemophagocytic histiocytes.

Case Report: Too Many Activated Immune Cells in a 9-Month-Old Boy

Jeffrey Lo, MD  |  August 12, 2020

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease of immune dysregulation characterized by unchecked inflammatory responses leading to end-organ dysfunction. Primary HLH results from inherited mutations that impair the capacity for immune regulation; secondary HLH arises from the inappropriate response to an immune stimulus, such as infection, malignancy or autoimmunity. What is less well known is…

Filed under:Conditions Tagged with:congenital disorder of glycosylation (CDG)genetic disordershemophagocytic lymphohistiocytosis (HLH)

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