Understanding the role of NLRP3 inflammasome activation in gout flares points to potential of NLRP3 inflammasome inhibitors as new treatment option.
Search results for: gout flare
FDA Approves Oral Solution of Colchicine to Prevent Gout Flare
The FDA approved an oral solution of colchicine for the prevention of gout flare in adults. Its dosage can be easily adjusted on the basis of patient needs.
How to Reduce Gout Flares
SAN DIEGO—If patients with gout keep their serum urate (SU) levels very low with urate-lowering therapy (ULT), they have fewer flares, according to a research abstract presented at ACR Convergence 2023.
FDA Approves Canakinumab to Treat Gout Flares
Canakinumab has received FDA approval for the treatment of patients with acute gout flares.
Shingles Vaccine Not the Only Immunization Linked with Gout Flare
NEW YORK (Reuters Health)—The recombinant shingles vaccine (RZV) is associated with an increased risk of gout flare, and a new study suggests other vaccines may trigger flares as well, researchers say. “Our findings are novel because for the first time, we have identified a trigger for gout flares that presumably acts through [an inflammatory] pathway,…
FDA Issues Boxed Warning for Febuxostat & Approves Colchicine for Gout Flare
The FDA has issued a boxed warning for febuxostat after a safety study found an increased risk of heart-related and other death in RA patients…
Canakinumab Reduces Risk for Gout Flares, But Not Serum Uric Acid Levels
An exploratory analysis of a canakinumab clinical trial has shown the interleukin 1β inhibitor may significantly reduce patients’ risk for gout flares. During the study, patients using canakinumab experienced this decreased risk, but the treatment did not change serum uric acid levels…
Sleep Apnea Tied to Gout Flares
NEW YORK (Reuters Health)—Sleep apnea may increase the risk of developing gout and experiencing flare-ups, according to a new study. Until now, little was known about the relationship between the two conditions, the study team writes in an article online Oct. 19 in Arthritis & Rheumatology. Obesity plays an important role in both sleep apnea…
Patients May Be Right: Tomatoes May Trigger Gout Flares
Dietary triggers of gout flares are associated with high levels of serum urate. A study recently uncovered an association between high serum urate and tomatoes, the first such link established beyond patient anecdotes…
Reducing Gout Flare Frequency Saves Money
A new data-driven study tracked and analyzed gout-related healthcare costs for more than three years, determining the financial burden of flares and the possible benefit of proper flare management…
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