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Editor's Pick

First ACR Guidance Statement for VEXAS Released

Ruth Jessen Hickman, MD  |  December 11, 2025

VEXAS is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. Given the variability in disease presentation & the limited number of studies to date, an international multidisciplinary panel of VEXAS experts was convened to provide guidance to healthcare providers on the condition’s management. We spoke to experts on the panel about the resulting guidance document.

Filed under:Clinical Criteria/GuidelinesConditionsFrom the CollegeGuidanceOther Rheumatic ConditionsResearch Rheum Tagged with:myelodysplastic syndromesrelapsing polychondritisSweet's syndromeUBA1VEXASVEXAS syndrome

The Great Debate: Ultrasound vs. Temporal Artery Biopsy in Giant Cell Arteritis

Michael Cammarata, MD, RhMSUS  |  December 10, 2025

In the ACR Convergence 2025 session, Great Debate: Ultrasound vs. Temporal Artery Biopsy in Giant Cell Arteritis, two vasculitis experts went head to head to determine the ideal first test in the diagnosis GCA: ultrasound or biopsy.

Filed under:ACR ConvergenceConditionsMeeting ReportsVasculitis Tagged with:ACR Convergence 2025ANCA-Associated VasculitisGiant Cell ArteritisThe Great Debate

A Liquid Biopsy for Lupus Nephritis?

Samantha C. Shapiro, MD  |  December 4, 2025

Urine biomarkers have the potential to change how lupus nephritis is managed, serving as a noninvasive means of early detection, assessing treatment response and more.

Filed under:ACR ConvergenceConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2025BiomarkersLupus nephritis supplementurinary biomarkers

Approaches to the Management of SLE During Pregnancy

Ruth Jessen Hickman, MD  |  November 14, 2025

At this ACR Convergence 2025 session, experts discussed disease management considerations to optimize outcomes in pregnant patients with SLE.

Filed under:ACR ConvergenceMeeting ReportsSjögren’s DiseaseSystemic Lupus ErythematosusSystemic Sclerosis Tagged with:ACR Convergence 2025ACR Convergence 2025 - LNLupuspatient carepregnancySjögren's Diseasesystemic lupus erythematosus (SLE)Treatment

ACR Releases New Guideline for Management of SLE at ACR 2025

Mithu Maheswaranathan, MD  |  November 14, 2025

Updating the last iteration in 1999, the new ACR Guideline for Management of SLE was unveiled at ACR Convergence 2025, providing rheumatologists an organ-based approach for therapeutic options for specific lupus manifestations.

Filed under:ACR ConvergenceClinical Criteria/GuidelinesConditionsGuidanceMeeting ReportsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2025BiologicsClinical Practice GuidelinesLupussystemic lupus erythematosus (SLE)

Complementary Medicine Meets Rheumatology: New Ways to Reduce Inflammation

Ruth Jessen Hickman, MD  |  November 14, 2025

At this ACR Convergence 2025 session, the speaker highlighted ways complementary and alternative medicine can be used alongside traditional medical treatments.

Filed under:ACR ConvergenceMeeting ReportsRheumatoid Arthritis Tagged with:ACR Convergence 2025ACR Convergence 2025 - RAComplementary and Alternative TherapiesDietstress managementsupplements

Why Target B Cells in SSc-ILD?

Katie Robinson  |  November 11, 2025

In a recent Arthritis & Rheumatology review article, three experts discuss the use of immunosuppressants to target B cells in a patient with systemic sclerosis-interstitial lung disease.

Filed under:Biologics/DMARDsConditionsDrug UpdatesResearch RheumSystemic Sclerosis Tagged with:B cellsCAR-T cell therapycase reportimmunosuppressioninterstitial lung disease (ILD)mycophenolate mofetilrituximabSSc-ILDSystemic sclerosis

Rheuminations: Address Ableism, Improve Care for All Patients

Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS  |  November 10, 2025

Ableism—discrimination against those with disabilities—distorts diagnostic reasoning & erodes patient trust. How can rheumatologists address this bias?

Filed under:EthicsOpinionRheuminations Tagged with:ableismAccess to carecommunicationdisabilityhealth disparitiespatient-centered care

Differentiating POTS from Other Conditions

Mary Beth Nierengarten  |  November 6, 2025

At a ACR Convergence 2025 session, two experts discussed POTS, the importance of considering dysautonomia when making a differential diagnosis & an interdisciplinary approach to treatment.

Filed under:ACR ConvergenceMeeting Reports Tagged with:ACR Convergence 2025DysautonomiaPOTS

Promising Combination Treatment for Gout

Michele B. Kaufman, PharmD, BCGP  |  October 27, 2025

The FDA has accepted a biologics license application for nano-encapsulated sirolimus with pegylated-adricase (NASP), a combination treatment designed to reduce serum uric acid levels in patients with uncontrolled gout.

Filed under:Biologics/DMARDsConditionsDrug UpdatesGout and Crystalline Arthritis Tagged with:FDAGoutnano-encapsulated sirolimus with pegylated-adricase (NASP)U.S. Food and Drug Administration (FDA)

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