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An official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals

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Diagnostic Challenges of MIS-C

Brian L.P. Dizon, MD, PhD, & Sangeeta Sule, MD, PhD  |  May 12, 2022

During the peak of the coronavirus pandemic in Washington, D.C., we were asked to evaluate a 14-year-old boy admitted to the pediatric hospitalist service. He had been healthy until two weeks before, when he noted a sore throat, and soon after he developed fevers and rashes without congestion, shortness of breath, conjunctivitis or swollen lymph…

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:COVID-19MIS-CMultisystem Inflammatory Syndrome in Children (MIS-C)

Case Report: Lipoma Arborescens of the Knee

John Nawrocki, MD, Kevin Hess, DO, & Maryah Mansoor, MBBS  |  May 12, 2022

Lipoma arborescens is a rare, benign intra-articular lesion characterized by diffuse replacement of synovial tissue by mature adipocytes, causing a villous lipomatous proliferation of the synovial membrane.1 Typically, this is a mono­articular condition, with the knee being the most commonly affected although it has been rarely reported to occur in an oligo-/polyarticular fashion and in…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:case reportGoutknee painlipoma arborescens

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Case Report: Blunt Smoker Denies Tobacco Use, Delaying Diagnosis

Rachel E. Elam, MD, ScM, Vishal Arora, MD, & Alyce M. Oliver, PhD, MD  |  May 12, 2022

Cannabis arteritis mirrors thrombo­angiitis obliterans in its clinical and arteriographic presentation, but its relevant exposure is cannabis rather than tobacco.1 Whether cannabis arteritis is a subset of thromboangiitis obliterans or a unique pathologic entity is debatable. Delta-9-tetrahydrocannabinol, the primary psychoactive component of cannabis, is a peripheral vasoconstrictor.2 This offers mechanistic insight into how cannabis may…

Filed under:Conditions Tagged with:cannabiscase reportmarijuanathromboangiitis obliteranstobacco

Case Report: An Uncommon Incidental Finding

Mia Robb Stahler & Michael Rosen, M  |  May 11, 2022

In certain ethnic populations and geographic locations, being a genetic carrier of sickle cell trait is common. Despite its prevalence, a recent report studied 100 mothers who were informed their newborn child had tested positive for sickle cell trait, and of these mothers less than half were aware of their carrier status prior to conception.1…

Filed under:Conditions Tagged with:case reportsickle cellsynovial analysis

Denosumab vs. Zoledronate: An Analysis of Treatments for Low Bone Mineral Density in Patients with HIV

Michele B. Kaufman, PharmD, BCGP  |  May 9, 2022

In a small study of men with low bone mineral density (BDM) living with HIV and taking anti-retroviral therapy, both zoledronate or denosumab were well tolerated and effective for bone mineral density of the lumbar spine and femoral neck.

Filed under:ConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:bone mineral density (BMD)denosumabHIVOsteoporosisosteoporosis treatmentszoledronate

Remission Definitions in RA: Common Questions & Implications for Clinical Practice

Samantha C. Shapiro, MD  |  May 5, 2022

A recent editorial provides new insights by reexamining the definitions of remission for rheumatoid arthritis and outlining concerns with the use of specific metrics for remission in clinical trials.

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Arthritis & RheumatologyC-reactive protein (CRP)Disease Activity Score (DAS)patient global assessment (PGA)RA Resource CenterRemissionRheumatoid Arthritis (RA)

New Tech Provides Insights Into the Pathogenesis of Psoriatic Arthritis

Maria de la Luz Garcia-Hernandez, PhD, & Christopher Ritchlin, MD, MPH  |  May 5, 2022

The etiology of psoriatic arthritis (PsA) is poorly understood but current evidence supports an interaction between genetic and environmental factors that coalesce to promote local tissue inflammation.1-3 The pivotal cytokines that underlie the local inflammatory response in a wide range of tissues are interleukin (IL) 23, IL-17 and tumor necrosis factor (TNF).4 The central contribution…

Filed under:ConditionsPsoriatic Arthritis Tagged with:Psoriatic Arthritis

Looking to Psoriatic Arthritis History to Disrupt Current Thinking

Rebecca H. Haberman, MD, & Jose U. Scher, MD  |  May 4, 2022

As the cloud moved away from the tent, Miriam’s skin suddenly became diseased, as white as snow. When Aaron turned toward her, he saw that she was diseased. —Numbers 12:10 For 29 years he [Fray Pedro de Urraca] was afflicted by … pain, suffering it at once in all the joints of his body, with…

Filed under:ConditionsPsoriatic Arthritis Tagged with:Psoriatic Arthritis

ACR Leaders to Meet with Members of Congress at May 12 Capitol Hill Event

From the College  |  April 25, 2022

The meetings will focus on legislation affecting rheumatology, including bills on graduate medical education and use of copay assistance funds.

Filed under:American College of RheumatologyLegislation & Advocacy Tagged with:ACR Capitol Hill visitcopay accumulatorsgraduate medical educationLegislation & Advocacypediatric loan repaymentprior authorizationstep therapy

Beating the Workforce Shortage: 4 Practices Share Best Practices in ACR Town Hall

Leslie Mertz, PhD  |  April 22, 2022

At a recent ACR town hall, four rheumatologists shared strategies that have helped them recruit new physicians amid a significant nationwide rheumatology workforce shortage.

Filed under:American College of RheumatologyWorkforce Tagged with:recruitmentWorkforceworkforce shortage

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