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New Consensus Recommendations Guide Sjögren’s Syndrome Management

Will Boggs, MD  |  November 25, 2019

NEW YORK (Reuters Health)—New consensus-based recommendations from the European League Against Rheumatism (EULAR) address the management of Sjögren’s syndrome with topical and systemic therapies. Sjögren’s syndrome presents with a broad spectrum of clinical manifestations and autoantibodies, including antinuclear antibodies (the most frequently detected), anti-Ro/SS-A (the most specific) and cryoglobulins and hypocomplementemia (the main prognostic markers)….

Filed under:ConditionsEULAR/OtherMeeting ReportsSjögren’s Disease Tagged with:EULARguidelinerecommendationsSjogren's

Rituximab-abbs Available in the U.S.; Plus Upadacitinib in Phase 3 Trials for PsA

Michele B. Kaufman, PharmD, BCGP  |  November 25, 2019

Rituximab-abbs, which is biosimilar to rituximab, is now available in the U.S. to treat specific cancers…

Filed under:Biologics/DMARDsConditionsDrug UpdatesPsoriatic Arthritis Tagged with:Cancernon-Hodgkin’s lymphomaPsoriatic Arthritisrituximabrituximab-abbsupadacitinib

Progress on Preventing Immune-Related Adverse Events

Mike Fillon  |  November 20, 2019

ATLANTA—One of the hottest topics in medicine is the emerging field of cancer immunotherapy. However, immune-related adverse events (irAEs) are associated with the therapy, and when things go wrong, they can go very, very wrong, said Ryan Sullivan, MD, during the 2019 ACR/ARP Annual Meeting in November. “The guiding principle of cancer immunotherapy is [that]…

Filed under:Conditions Tagged with:2019 ACR/ARP Annual MeetingBiomarkersCancerCheckpoint Inhibitorsimmune-related adverse events

New Draft Gout Guideline Released

Susan Bernstein  |  November 20, 2019

ATLANTA—The authors of the new draft ACR treatment guideline for the management of gout presented the draft guideline on Nov. 13 at the 2019 ACR/ARP Annual Meeting. Based on evidence from more than 130 published studies, there are 42 recommendations, of which 16 were strong, including 27 for urate-lowering therapy (ULT) management, 13 of which…

Filed under:Clinical Criteria/GuidelinesConditionsGout and Crystalline Arthritis Tagged with:2019 ACR/ARP Annual MeetingGout

FDA Action on Loperamide Misuse; Plus Phase 1 Trials for BAT2506 Biosimilar Begin

Michele B. Kaufman, PharmD, BCGP  |  November 20, 2019

The FDA has limited the package size of some over-the-counter loperamide products to prevent its potential misuse and abuse…

Filed under:Biologics/DMARDsDrug Updates Tagged with:abuseBAT2506FDAGolimumabloperamideU.S. Food and Drug Administration (FDA)

Management of Meniscal Tears: Surgery May Not Be Necessary

Lara C. Pullen, PhD  |  November 18, 2019

Patients with meniscal tear experience similar levels of reduced pain and improved physical function when treated with either arthroscopic partial meniscectomy or physical therapy, according to a recent study. The study also found these improvements were long term—lasting through the five-year follow up…

Filed under:ConditionsOsteoarthritis and Bone DisordersResearch Rheum Tagged with:Arthritis & Rheumatologykneeknee injuryKnee Osteoarthritis (OA)meniscal tearsurgery

Figures 1 & 2: Transverse and longitudinal ultrasound views, respectively, of the left posterior knee, revealing a cystic mass with heterogeneous internal echotexture and no stalk.

Ultrasound Aids Diagnosis of Man with Knee Pain & Swelling

Mark H. Greenberg, MD, RMSK, RhMSUS, Prem Patel, Elijah Mitcham, MD, James W. Fant Jr., MD, & Frank R. Voss, MD  |  November 17, 2019

A 56-year-old automobile mechanic was referred to our rheumatology service by his orthopedist to evaluate left posterior knee pain and swelling that had been present for three months. The patient had undergone bilateral total knee arthroplasties (TKAs) for sports-related osteo­arthritis three years before. In addition to the knee pain, the patient described several years of…

Filed under:ConditionsRheumatoid Arthritis Tagged with:knee arthroplastyknee swellingpopliteal cystsynovitis

The 2019 ARP Awards of Distinction & ACR Masters

Carol Patton, with Keri Losavio  |  November 16, 2019

ATLANTA—At the 2019 ACR/ARP Annual Meeting in November, the ACR and the ARP honored a group of distinguished individuals who have made significant contributions to rheumatology research, education and patient care. This month, The Rheumatologist speaks with the winners of the ARP Merit Awards about their individual contributions to advancing rheumatology. You’ll also find a…

Filed under:Awards Tagged with:2019 ACR/ARP Annual MeetingAnnelle ReedAssociation of Rheumatology Professionals (ARP)Dana GuglielmoDr. Calvin R. Brown Jr.Dr. Carlos PinedaDr. Chester V. OddisDr. Fredrica E. SmithDr. Gerd R. BurmesterDr. Geri NeubergerDr. Grant W. CannonDr. Hani El-GabalawyDr. J. Lee NelsonDr. James N. JarvisDr. John D. ReveilleDr. John J. O’SheaDr. Jonathan S. CoblynDr. Jürgen BraunDr. Lee Stuart SimonDr. Linda Kay MyersDr. Michelle A. PetriDr. Nighat Mir AhmadDr. Ronald M. LaxerDr. Rosalind Ramsey-GoldmanDr. Rowland W. ChangDr. Sharad LakhanpalDr. Simon HelfgottDr. William F.C. RigbyHeather BenhamJoni DeanMichael LaValleyMonique GignacRobert Richardson

Google Signs Healthcare Data & Cloud Computing Deal with Ascension

Reuters Staff  |  November 13, 2019

(Reuters)—Alphabet Inc.’s Google signed its biggest cloud computing customer in healthcare yet, according to an announcement on Monday, gaining with the deal datasets that could help it tune potentially lucrative artificial intelligence tools. The Wall Street Journal earlier reported Google teaming up with Ascension to collect personal health-related information of millions of Americans across 21…

Filed under:Information TechnologyTechnology Tagged with:AscensiondataGoogleHealth Information Technologypatient data

Insight into Achieving & Maintaining Target Serum Urate Levels in Gout Patients

Lara C. Pullen, PhD  |  November 11, 2019

A recent study advances the understanding of factors associated with a target serum urate level of 6 mg/dL or less. Researchers found such factors as having a rheumatologist as the main provider of gout care contributed to achieving and maintaining this outcome. However, the presence of co-morbidities lowered a patient’s chances for achieving the target serum urate level, even with allopurinol use…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:AllopurinolGoutserum urate levels

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