The CMS has implemented a few changes to its 2018 MIPS submission categories. Not only will it be adding a cost category, but it has recently announced the renaming of the Advancing Care Information (ACI) category to Promoting Interoperability (PI) to focus on interoperability, improving flexibility and relieving administrative burdens. The CMS confirmed this will…
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ACR Investigates PAMA Impact on Lab Testing
Rapid, accurate and convenient point-of-care lab testing for patients is one of the promises of 21st century medicine. However, reimbursement cuts enacted through the Protecting Access to Medicare Act of 2014 (PAMA) threaten access to this testing, explains Colin Edgerton, MD, FACP, RhMSUS, partner in Articularis Healthcare and chair of the ACR’s Committee on Rheumatologic…

A Comprehensive Review of NSAID Cardiovascular Toxicity
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most used drugs for acute and chronic pain. More than 30 billion doses of NSAIDs are consumed annually from more than 70 million prescriptions.1 Despite their common use, NSAIDs are not free of serious toxicities. In the pre-Vioxx (rofecoxib) era, gastrointestinal toxicity was the primary concern for many NSAIDs….

The Rate of Disability in Pediatric Patients with SLE
Recent research found 41% of pediatric patients with SLE are affected by at least mild disability, with higher pain scores correlating with increased disability. Mary Beth Son, MD, says determining how these children feel and what affects them daily is vital to “identifying targets we can hit as clinicians to improve their quality of life.”

Results from Belimumab Safety Study
In a long-term extension study, belimumab proved safe, demonstrating low organ damage accrual in SLE patients treated for up to nine years…

Neutrophils & B Cells Create Unique Antibodies in Lupus Patients
NETs or LL37-DNA complexes may serve as future targets for SLE therapy. In a recent study, researchers identified a link between neutrophils and NETs, and the activation of self-reactive B cells. Their study describes a neutrophil-B cell interaction unique to lupus…

FDA Approves Combination Therapy for OA Pain, but Not Duobrii Lotion for Plaque Psoriasis
The FDA has approved a combination of amlodipine and celecoxib, which may lower serum creatinine, for treating osteoarthritis pain and hypertension…
Anticonvulsants Unhelpful for Low Back Pain
NEW YORK (Reuters Health)—Solid evidence suggests that anticonvulsants provide no benefit for low back or lumbar radicular pain and a high risk of harm, researchers say. “We started the study because these drugs were increasingly being used for low back pain and radiating leg pain, without the support of strong evidence of effectiveness,” principal investigator…

IV Tramadol Promising for Postoperative Pain; FDA Denies IV Meloxicam Approval
In its first phase 3 clinical trial, intravenous tramadol has met its primary endpoint for relieving postoperative pain…

FDA Approves Baricitinib for RA Patients
The FDA has approved baricitinib in a 2 mg tablet dose to treat patients with moderate to severe active rheumatoid arthritis…
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