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Rheumatologists Respond to Prescription Opioid Analgesic Crisis

Larry Beresford  |  May 16, 2017

The alarming statistics on prescription opioid overdoses are well known to medical professionals, thanks to the Centers for Disease Control and Prevention (CDC)’s widely cited finding that deaths from opioid analgesics have increased fourfold since 1999.1 Half of all fatal drug overdoses now involve opioids prescribed by a doctor. Meanwhile, a lack of rigorous research…

Filed under:AnalgesicsConditionsDrug UpdatesPain SyndromesPractice Support Tagged with:AddictionanalgesicChronic painepidemicManagementopioidOverdosepatient careprescriptionRheumatic DiseaserheumatologistrheumatologyriskSafetyTreatment

Strategies for Successful Joint Replacement Surgery

Carina Stanton  |  May 16, 2017

Collaboration among all providers—surgeon, rheumatologist, physical therapist, etc.—is essential for patients with a rheumatic disease who are about to undergo total joint arthroplasty to reach their goals, including reduced pain and improved mobility…

Filed under:ConditionsOsteoarthritis and Bone Disorders Tagged with:Joint Surgerykneeknee arthroplastysurgerytotal joint arthroplastytotal knee replacement

Bigger, More Expensive Healthcare Practices Not Necessarily Better

Ronnie Cohen  |  May 15, 2017

(Reuters Health)—You might not get what you pay for when it comes to healthcare, a new study hints. A report in Health Affairs on May 2 found little association between how much physician practices charged and patients’ perceptions of their quality of care.1 “We’re asking consumers to make a lot of decisions about healthcare purchasing…

Filed under:Practice Support Tagged with:alternative therapiescostsHealth carepatient care

Cracking, Popping Joints May Foretell Arthritis

Carolyn Crist  |  May 11, 2017

(Reuters Health)—Grating, cracking or popping sounds around joints may predict future arthritis, especially in the knees, according to a recent U.S. study. Among thousands of people with no knee pain who were followed for three years, one quarter had noisy knees yet they made up three quarters of the cases of symptomatic knee arthritis that…

Filed under:ConditionsEducation & TrainingOsteoarthritis and Bone DisordersPractice Support Tagged with:Arthritiscracking jointscrepitusknee painpopping joints

Pricey Arthritis Drug Effective in Small Fraction of Ulcerative Colitis Cases

Gene Emery  |  May 9, 2017

NEW YORK (Reuters Health)—Pfizer’s expensive arthritis drug tofacitinib has been shown to produce a remission in nearly 1 in 5 patients with moderate to severe ulcerative colitis, but long-term remission persists in fewer than half of those cases. In a series of studies published in the May 4 New England Journal of Medicine, researchers reported…

Filed under:Biologics/DMARDsDrug Updates Tagged with:Tofacitinibulcerative colitis

Institute for Clinical Economic Review Final Report on RA Treatments

Mary Beth Nierengarten  |  May 4, 2017

On April 7, 2017, the Institute for Clinical and Economic Review (ICER) published its final report, titled, Targeted Immune Modulators for Rheumatoid Arthritis: Effectiveness & Value.1 The stated objective of the report was to assess the comparative clinical effectiveness of the targeted immune modulators (TIMs) used to treat patients with moderate to severe active rheumatoid…

Filed under:Drug UpdatesPractice SupportProfessional TopicsRheumatoid Arthritis Tagged with:Institute for Clinical and Economic Review (ICER)targeted immune modulators (TIMs)Targeted Immune Modulators for Rheumatoid Arthritis: Effectiveness & Value

FDA to Review Immediate-Release Oxycodone; Plus NICE Recommends Secukinumab

Michele B. Kaufman, PharmD, BCGP  |  May 1, 2017

A new formulation of oxycodone in 10 and 15 mg doses is being reviewed by the FDA for treating pain…

Filed under:AnalgesicsBiologics/DMARDsConditionsDrug UpdatesPsoriatic Arthritis Tagged with:FDAFood and Drug AdministrationOpioidspsoriatic arthritissecukinumab

Baricitinib Approval Stalls; Plus No REMS for Erythropoiesis-Stimulating Agents

Michele B. Kaufman, PharmD, BCGP  |  April 28, 2017

The FDA has declined to approve baricitinib to treat rheumatoid arthritis, citing the need for more data on dosing and safety…

Filed under:Biologics/DMARDsDrug Updates Tagged with:baricitiniberythropoiesis-stimulating agents (ESAs)FDAFood and Drug AdministrationRheumatoid Arthritis (RA)

Tofacitinib Treatment May Improve Nail Psoriasis

Rita Buckley  |  April 24, 2017

NEW YORK (Reuters Health)—The oral Janus kinase (JAK) inhibitor tofacitinib appears to improve moderate to severe nail psoriasis, according to a new study. “Nails are hard to treat in psoriasis and we need better treatments,” says Dr. Luis Garza, a dermatologist at Johns Hopkins School of Medicine in Baltimore, who was not involved in the research….

Filed under:ConditionsPsoriatic ArthritisSystemic Sclerosis Tagged with:nailsplaque psoriasisPsoriasispsoriatic arthritisTofacitinib

NKTR-181 Promising for Chronic Low Back Pain

Michele B. Kaufman, PharmD, BCGP  |  April 21, 2017

NKTR-181, a mu-opioid agonist analgesic, has proved safe and effective for treating chronic low back pain vs. placebo in a recent clinical trial…

Filed under:AnalgesicsConditionsDrug UpdatesPain Syndromes Tagged with:Chronic painlow back painNKTR-181Pain

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