NEW YORK (Reuters Health)—A father’s exposure to methotrexate 90 days or less before conception “should not be of major concern,” researchers say. Prepregnancy paternal methotrexate exposure appears to confer no increased risk of major or minor congenital malformation, stillbirth or preterm birth in his offspring, their study found. Methotrexate is a first-line therapy for rheumatoid…
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How to Diagnose Antisynthetase Syndrome
Antisynthetase syndrome (AS) is strongly associated with the presence of antibodies to aminoacyl-transfer RNA (tRNA) synthetases (ARSs) that are implicated in the pathogenesis of myositis and interstitial lung disease (ILD). Antibodies against eight antisynthetases have been identified and are detected in 16–26% of patients with idiopathic inflammatory myopathies (IIM).1 Serum assays for five of these…
ACR Puts Forward Principles on Patient Access to Care
The ACR has partnered with the American Medical Association (AMA) and over a dozen stakeholder groups to create a set of 21 principles to reform prior authorization protocols. This coalition represents hospitals, medical groups, patients, pharmacists and physicians with a unified goal of creating a more patient-centered, streamlined and transparent process for prior authorization. According…
ACR Joins Opposition to Proposed Healthcare Replacement Bill as Written
The ACR is joining a chorus of voices asking Congress to reconsider several key provisions in the proposed American Health Care Act (AHCA) that it feels could have a detrimental effect on patients. Characterized as a replacement to the Affordable Care Act (ACA), the AHCA eliminates a number of provisions found in the ACA, although…
Time to Rethink Inpatient Rehab After Knee Replacement?
NEW YORK (Reuters Health)—Inpatient rehabilitation did not lead to better mobility following total knee replacement compared with a home-based program in a randomized controlled trial (RCT) conducted in Australia. The findings do not support inpatient rehabilitation for adults undergoing uncomplicated total knee arthroplasty, conclude the authors in JAMA on March 14.1 “Normally, one study is…
Spinal Underwear May Relieve Lower Back Pain
A recent study in nurses and healthcare professionals examined the efficacy of a novel ergonomic aid for managing low back pain. After a three-month trial, researchers found that the aid, Spinal Underwear, reduced low back pain, suggesting that musculoskeletal symptoms may be influenced by posture and somatization…
U.S. Doctors in Training to Work Longer Hours Under New Guidelines
(Reuters Health)—Days may get a lot longer for some doctors in training after the group that oversees medical education in the U.S. rolled back controversial rules limiting the number of hours first-year residents may work. Beginning July 1, doctors in their first year of training after medical school may once again care for patients for…
Brodalumab Approved for Plaque Psoriasis
Brodalumab has received FDA approval for treating plaque psoriasis in adults, with a Boxed Warning against prescribing it for patients with a history of suicidal thoughts or behavior…
Moderate Alcohol Intake Decreases SLE Risk in Women
Beer, wine, liquor—alcohol contains elements that suppress systemic inflammation, and its consumption has been linked to reduced risk of cardiovascular disease and RA. A recent analysis examined the effect of alcohol on SLE risk in women from the two Nurses’ Health Study cohorts. The results: Researchers found an inverse association between moderate alcohol consumption and SLE risk—with a 39% reduction in SLE risk among women who consumed about half a drink of alcohol daily…
U.S. Republicans Unveil Plan to Dismantle Obamacare, Critics Pounce
WASHINGTON (Reuters)—Long-awaited legislation to dismantle Obamacare was unwrapped on Monday by U.S. Republicans, who called for ending health insurance mandates and rolling back extra healthcare funding for the poor in a package that drew immediate fire from Democrats. In a battle waged since the 2010 passage of the Affordable Care Act, Democratic President Barack Obama’s…
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