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Search results for: methotrexate

Recent Research: Study Summaries from Arthritis Care & Research

Meghan Angley, PhD, & S. Sam Lim, MD, Tiffany Dharia, MD, & Michael George, MD, Emily F. Neves Yuki, PhD, & Eloisa Bonfa, PhD  |  May 12, 2022

Lupus & Perinatal Outcomes Adverse perinatal outcomes before & after diagnosis with systemic lupus erythematosus among African American Women By Meghan Angley, PhD, & S. Sam Lim, MD Why was this study done? Previous studies have suggested that women with systemic lupus erythematosus (SLE) may experience adverse perinatal outcomes, including preterm and small-for-gestational-age birth, in…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:AC&RArthritis Care & ResearchCOVID-19FlaresReading Rheumvaccination

Bernard Chantal / shutterstock.com

Diagnostic Challenges of MIS-C

Brian L.P. Dizon, MD, PhD, & Sangeeta Sule, MD, PhD  |  May 12, 2022

During the peak of the coronavirus pandemic in Washington, D.C., we were asked to evaluate a 14-year-old boy admitted to the pediatric hospitalist service. He had been healthy until two weeks before, when he noted a sore throat, and soon after he developed fevers and rashes without congestion, shortness of breath, conjunctivitis or swollen lymph…

Filed under:ConditionsOther Rheumatic ConditionsPediatric Conditions Tagged with:COVID-19MIS-CMultisystem Inflammatory Syndrome in Children (MIS-C)

Medication Preferences & Current Practices for PsA

Michele B. Kaufman, PharmD, BCGP  |  May 11, 2022

With many new agents designed to treat PsA, rheumatologists and patients have options. Schwartzman et al. examined the real-world use of different treatments and ranked patient medication preferences.

Filed under:ACR ConvergenceConditionsDrug UpdatesMeeting ReportsPsoriatic Arthritis Tagged with:ACR Convergence 2021PsAPsoriatic Arthritis

Imaging of Axial Psoriatic Arthritis

Walter P. Maksymowych, MB ChB, FACP, FRCP(C)  |  May 9, 2022

The axial phenotype of psoriatic arthritis (axPsA) is an excellent example of a major controversy in rheumatology that has become the focus of attention because of the emergence of new therapies with different mechanisms of action for alleviating joint inflammation. It was first described in 1961 but, until recently, it has largely remained under the…

Filed under:Axial SpondyloarthritisConditionsPsoriatic Arthritis Tagged with:Ankylosing SpondylitisAxial Psoriatic Arthritis (axPsA)axial skeletal inflammationMagnetic resonance imaging (MRI)Psoriatic ArthritisradiographX-ray

Risk of Adverse Outcomes Due to COVID-19 May Be Lower with TNF Inhibitor Monotherapy

Katie Robinson  |  May 5, 2022

Findings support the continued use of TNF inhibitor monotherapy in individuals with immune-mediated inflammatory diseases. In the study, these patients had a lower risk of hospitalization or death caused by COVID-19 than patients on other commonly prescribed treatment regimens

Filed under:Conditions Tagged with:COVID-19COVID-19 Global Rheumatology Allianceimmune-mediated inflammatory diseases (IMIDs)monotherapyTNF inhibitors

Anifrolumab Promising for Sustained Low Disease Activity in Patients with Lupus

Michele B. Kaufman, PharmD, BCGP  |  May 5, 2022

ACR CONVERGENCE 2021—Using pooled data from the TULIP-1 and TULIP-2 clinical trials, researchers set out to identify whether more patients with systemic lupus erythematosus (SLE) being treated with anifrolumab achieved a low disease activity state than patients with SLE who received placebo.1-3 An analysis of the data was presented at ACR Convergence 2021 by Eric…

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2021anifrolumabSLEsystemic lupus erythematosus (SLE)

2 New Clinical Practice Guidelines for JIA Released

Ruth Jessen Hickman, MD  |  April 20, 2022

Two new ACR Clinical Practice Guidelines provide recommendations on the pharmacologic management of JIA, focusing on treatment of oligoarthritis, temporomandibular arthritis & systemic JIA, as well as nonpharmacologic therapies, medication monitoring, immunizations & imaging.

Filed under:Uncategorized

ARCTIC Rewind: Effects of Half Dose of csDMARDs in Patients with RA in Remission

Lara C. Pullen, PhD  |  April 20, 2022

A study examined the effect of reducing the dose of conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) by half in patients with RA in remission, finding the change increased the incidence of flare in 25% of patients.

Filed under:Uncategorized

FDA Approves Risankizumab-rzaa for PsA

Michele B. Kaufman, PharmD, BCGP  |  April 20, 2022

Two recent trials demonstrated the safety and efficacy of risankizumab-rzaa for the treatment of adults with active psoriatic arthritis.

Filed under:Biologics/DMARDsDrug Updates Tagged with:FDA approvalPsAPsoriatic Arthritisrisankizumab-rzaaU.S. Food and Drug Administration (FDA)

Study: COVID-19 Vaccinations Are Safe for Patients with Lupus

Thomas R. Collins  |  April 15, 2022

COVID-19 vaccinations are safe for patients with systemic lupus erythematosus (SLE), with manageable side effects and a low incidence of flare, according to a recently published study in The Lancet.1 The use of mRNA vaccines, such as those from Pfizer-BioNTech and Moderna, which have been viewed as riskier than traditional vaccines because of a concern…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:COVID-19vaccination

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