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Search results for: pain

mRNA CAR T Cell Therapy Receives FDA’s Rare Pediatric Designation to Treat Juvenile Dermatomyositis

Michele B. Kaufman, PharmD, BCGP  |  January 30, 2025

FDA has granted Descartes-08, an mRNA chimeric antigen receptor T cell therapy, a rare pediatric disease designation for the treatment of juvenile dermatomyositis.

Filed under:Biologics/DMARDsConditionsDrug UpdatesMyositis Tagged with:chimeric antigen receptor T (CAR-T) cellsFDAjuvenile dermatomyositisU.S. Food and Drug Administration (FDA)

Reproductive Health, Biosimilars & More in Focus at SOTA 2025

Ruth Jessen Hickman, MD  |  January 30, 2025

Reproductive health, biosimilars, IgG4-related disease and much more—five speakers give us a sneak peek into important topics being addressed at the ACR’s 2025 State-of-the-Art Clinical Symposium, April 4–6.

Filed under:Biologics/DMARDsConditionsEducation & TrainingGuidanceMeeting ReportsOther ACR meetings Tagged with:ACR State-of-the-Art Clinical SymposiumBiosimilarsIgG4 related diseaseLupusOsteoporosispregnancypregnancy complicationspregnant womenskinState-of-the-Art Clinical Symposium

Precision Medicine on a Population Level: Can Digital Health Technology Improve Access to Rheumatologic Care?

Daniel H. Solomon, MD, MPH, & Andrew Concoff, MD, FACR  |  January 16, 2025

Over our 25 years as rheumatologists, care has advanced greatly. We each completed our rheumatology training in the late 1990s when both infliximab and etanercept first arrived on the U.S. market, ushering in the era of biologics in rheumatology. Since this time, our greater understanding of the immunologic basis of many rheumatic diseases has translated…

Filed under:ConditionsOpinionPractice SupportRheumatoid ArthritisSpeak Out RheumTechnology Tagged with:mPROscheduling app

Adobe Stock | Creativa Images

RA: How High Is the Toll?

Samantha C. Shapiro, MD  |  January 9, 2025

Patients with RA not only suffer from functional limitations, but also face increased healthcare costs, primarily due to prescription drug use, says Dr. Yinan Huang.

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:economic burdenMSPhDphysical burdenRA Resource CenterYinan Huang

Rheuminations: Imagine a Better World for Clinicians & Our Patients

Bharat Kumar, MD, MME, FACP, FAAAAI, RhMSUS  |  January 8, 2025

The world didn’t end on Jan. 1, 2000. The Y2K bug didn’t crash airplanes and liquidate bank assets. We were, overall, hopeful for the future—a new millennium full of futuristic visions of a techno-utopia. Fast forward a quarter of a century and we now live in that technologically advanced age that once seemed so far…

Filed under:OpinionPatient PerspectiveRheuminationsWorkforce

Sleep Disorders & Rheumatic Disease

Thomas R. Collins  |  January 1, 2025

ACR Convergence 2024—With poor sleep a major complaint among patients with rheumatologic diseases, physicians should hone their understanding of how the body regulates sleep and how this system can be disrupted, and tailor their management plans to help patients with these issues, panelists said in a session at ACR Convergence. For some patients, their struggles…

Filed under:ACR ConvergenceConditionsMeeting Reports Tagged with:Sleepsleep disorder

Under Pressure: Understanding Dysautonomia & POTS

Jason Liebowitz, MD, FACR  |  January 1, 2025

Brit Adler, MD, provided a detailed analysis into the symptoms and management of patients with postural orthostatic tachycardia syndrome.

Filed under:ConditionsEULAR/OtherMeeting Reports Tagged with:autonomic nervous systemDysautonomiapostural orthostatic tachycardia syndrome (POTS)

FDA Approves Bimekizumab-bkzx (Bimzelx) for 3 New Rheumatic Indications

Michele B. Kaufman, PharmD, BCGP  |  December 30, 2024

The FDA has approved bimekizumab-bkzx for the treatment of adults with psoriatic arthritis, non-radiographic axial spondyloarthritis and ankylosing spondylitis.

Filed under:Axial SpondyloarthritisBiologics/DMARDsConditionsDrug UpdatesPsoriatic Arthritis Tagged with:Ankylosing Spondylitisbimekizumab-bkzxFDA approvalnon-radiographic axial spondyloarthritisnr-axSpAPsoriatic ArthritisU.S. Food and Drug Administration (FDA)

ARP Celebrates 58 Years of Achievements & Transformations, Identifies Challenges

Thomas R. Collins  |  December 27, 2024

ACR Convergence 2024—In a wide-ranging and engaging discussion, members of the Association of Rheumatology Professionals (ARP) tracked their progress over the years across clinical practice, research production and representation in the field, while outlining challenges and opportunities to come. The session at ACR Convergence included a panel and an audience full of past presidents of…

Filed under:ACR ConvergenceMeeting Reports Tagged with:Association of Rheumatology Professionals (ARP)

The Identification & Management of Hypophosphatasia

Colin Ligon, MD, MHS  |  December 10, 2024

With the U.S. Food & Drug Administration’s approval in 2014 of asfotase alfa for replacement of tissue-non-specific alkaline phosphatase (TNSALP or TNAP) in juvenile-onset hypophosphatasia (HPP), rheumatologists have a responsibility to recognize the more subtle manifestations of this condition in adults to avoid missed treatment opportunities for fractures, dental loss and musculoskeletal pain. Hypophosphatasia is…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:genetic disordersHypophosphatasia

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