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Search results for: psoriasis

Revised Application Expected for IV Meloxicam; Plus EU Approves Tildrakizumab

Michele B. Kaufman, PharmD, BCGP  |  October 9, 2018

After meeting with the FDA, the makers of intravenous meloxicam plan to resubmit the treatment’s new drug application…

Filed under:AnalgesicsConditionsDrug UpdatesPain Syndromes Tagged with:Chronic painEU approvalFDAmeloxicamPainplaque psoriasistildrakizumabU.S. Food and Drug Administration (FDA)

More Evidence TNF Inhibitors Raise Risk of Peripheral Neuropathy

Megan Brooks  |  October 8, 2018

NEW YORK (Reuters Health)—A large epidemiological study provides more evidence of a link between tumor necrosis factor inhibitors (TNFi) and peripheral neuropathy (PN). “These events are rare and the benefit of these drugs still outweigh this risk so this should not change practice,” cautions first author Dr. Mahyar Etminan from the University of British Columbia…

Filed under:Drug Updates Tagged with:Peripheral NeuropathyTNF inhibitorstumor necrosis factortumor necrosis factor (TNF) inhibitors

Celiac Awareness Makes a Difference for Rheumatology Patients

Carina Stanton  |  September 24, 2018

Celiac disease and gluten sensitivity are difficult to diagnose, but they affect multiple systems and are associated with other autoimmune diseases. Lan Chen, MD, PhD, believes better testing and clearer education will be a gamechanger for celiac patients…

Filed under:Conditions Tagged with:celiac diseaseDiagnosisgluten

California Insurance Commissioner Sues AbbVie over Humira

Natasha Yetman  |  September 23, 2018

(Reuters)—On Tuesday, Insurance Commissioner Dave Jones filed a complaint on behalf of the State of California against AbbVie Inc., alleging the drugmaker gave illegal kickbacks to healthcare providers to prescribe its blockbuster drug, Humira. The regulator alleged that AbbVie engaged in a far-reaching scheme including cash, meals, drinks, gifts, trips and patient referrals, as well…

Filed under:Biologics/DMARDsDrug Updates Tagged with:adalimumabHumiralawsuitLegal

Case Report: A Psoriatic Arthritis Patient with Dactylitis & Enthesitis

Samantha C. Shapiro, MD; Jemima Albayda, MD; & Ana-Maria Orbai, MD, MHS  |  September 20, 2018

A 36-year-old woman presented at the Johns Hopkins Arthritis Center for a second opinion regarding a diagnosis of psoriatic arthritis (PsA). One year prior to our evaluation, she had developed pain and stiffness in her hands, feet, knees, ankles, elbows and shoulders. She had mild plaque psoriasis of the scalp and base of the neck,…

Filed under:ConditionsOther Rheumatic ConditionsPsoriatic Arthritis Tagged with:DactylitisEnthesitisPsAPsoriatic Arthritis

Join Us Virtually for the 2018 Annual Meeting with ACR Beyond Live!

From the College  |  September 16, 2018

Join us virtually in Chicago, as we stream the 2018 ACR Review Course and ACR/ARHP Annual Meeting live. Registration is now open, and the events will take place Oct. 20‒24. Watch the sessions live in real time, chat with other attendees, and participate in question-and-answer sessions when available. You can also enjoy access to the…

Filed under:From the College Tagged with:2018 ACR/ARHP Annual Meetingvideo streaming

Psoriatic Arthritis Research Continues Hunt for Biomarkers

Thomas R. Collins  |  August 17, 2018

AMSTERDAM—Molecular signatures in synovial tissue that can be gathered through biopsies are a largely untapped resource that could help guide treatment for rheumatic conditions, an expert said at the EULAR: Annual European Congress of Rheumatology. “I’m convinced that looking into synovial tissue provides us with tools to not only understand mechanisms of disease in rheumatoid…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:BiomarkersC-reactive protein (CRP)PsAsynovial biopsies

Study Says 1 Biosimilar Switch Is OK; Jury Still Out on Multiple Switches

Thomas R. Collins  |  August 17, 2018

AMSTERDAM—As more biosimilar drugs for rheumatic diseases make their way to market, evidence is growing that switching from the originator drug to a biosimilar tends to be effective, while the questions of switching back and forth, and switching multiple times using several different biosimilars, remain to be answered, an expert on the topic said at…

Filed under:Biologics/DMARDsDrug Updates Tagged with:adalimumabbiosimilar substitutionsEnbreletanerceptHumiraINFLECTRA (infliximabdyyb)REMICADE (infliximab)Rituxanrituximab

Adalimumab Appears Safe for Treating Pediatric Patients with Autoimmune Disease

Reuters Staff  |  August 8, 2018

NEW YORK (Reuters Health)—Adalimumab appears to be safe for treating pediatric patients with polyarticular juvenile idiopathic arthritis (JIA), enthesitis-related arthritis (ERA), psoriasis and Crohn’s disease (CD), according to data from company-sponsored clinical trials. Adalimumab is an anti-tumor necrosis factor monoclonal antibody with demonstrated efficacy in these conditions, but pediatric safety data remains limited. Dr. Gerd…

Filed under:ConditionsDrug Updates Tagged with:adalimumabCrohn's disease (CD)enthesitis-related arthritis (ERA)polyarticular juvenile idiopathic arthritis (JIA)Psoriasis

EU Grants Marketing Authorization for Hyrimoz; Plus FDA Rejects New Drug Application for Buprenorphine Sublingual Spray

Michele B. Kaufman, PharmD, BCGP  |  August 8, 2018

In late July, the European Commission granted marketing approval for Hyrimoz, which is biosimilar to adalimumab…

Filed under:AnalgesicsBiologics/DMARDsDrug Updates Tagged with:adalimumabBiologics & BiosimilarsBiosimilarsbuprenorphine sublingual sprayDrug SafetyEuropean UnionFDAHyrimozInternationalPainSafetyU.S. Food and Drug Administration (FDA)

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