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Articles tagged with "environmental factor"

1 Step Closer: Study Examines Factors That Lead to RA in Hope of Developing Prevention Strategies

Linda Childers  |  November 4, 2020

Research has found blood tests detect elevations of autoantibody isotypes in patients years before they are diagnosed with rheumatoid arthritis (RA). According to Kevin Deane, MD, PhD, identifying patients during this pre-RA period may be key to preventing or delaying the onset of RA.

Can Lupus Be Prevented? Research Reveals Clues to Who’s Most Likely to Transition to Classified Disease

Susan Bernstein  |  February 25, 2020

How does a patient transition from health to active SLE? This question is the crux of the research conducted by Judith A. James, MD, PhD, and colleagues…

Hair dye being applied to a man’s beard.

Case Report: A 50-Year-Old Man Suffers Dye-Induced Arthritis

Hrudya Abraham, MD, Eric Warm, MD, FACP, & Avis Ware, MD  |  December 18, 2019

Hair dye products are commonly used by both men and women to enhance youth and beauty and to follow fashion trends. As reported in the medical literature, hair dyes and their ingredients are associated with allergic contact dermatitis. A possible association with joint inflammation has also been recognized. There is literature to support that para-phenylenediamine…

Atmospheric & Environmental Changes Tied to Organ-Specific Lupus Flares

Megan Brooks  |  November 19, 2019

NEW YORK (Reuters Health)—Changes in atmospheric and environmental factors may contribute to organ-specific disease exacerbation in patients with systemic lupus erythematosus (SLE), according to a new study. The study found “strong associations between atmospheric variables and fine particulate matter concentration over the 10 days prior to a patient visit and organ-specific lupus flares at the…

To Understand Lupus, Study the Gut

Elizabeth Hofheinz, MPH, MEd  |  September 17, 2019

Researchers who devote their time to studying lupus are accustomed to considering environmental stimuli such as sunshine and cigarettes. But according to Gregg J. Silverman, MD, a professor in the Department of Medicine and in the Department of Pathology at the New York University (NYU) School of Medicine and co-director of the Musculoskeletal Center of…

Clusters of Autoimmune Liver Disease Suggest Environmental Trigger

Reuters Staff  |  April 17, 2019

NEW YORK (Reuters Health)—A large population-based study from the U.K. provides more evidence that some autoimmune liver diseases may be triggered by exposure to something in the environment. The study found a significant clustering of cases of primary biliary cholangitis (PBC), autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC) in well-defined regions of north-east England…

Is Chemical Exposure Linked to DNA Methylation Dysregulation in SLE Patients?

Carina Stanton  |  June 5, 2018

Could your lupus patients benefit from limiting exposure to chemicals at home and in the medical environment? It’s a strong possibility, according to the preliminary findings of a research team investigating DNA methylation disruption in patients with SLE…

Gut Microbiota Directly Affects Inflammatory Arthritis

Lara C. Pullen, PhD  |  May 8, 2018

Gut microbiota may provide insight into important environmental triggers for autoimmune diseases. New research in mice indicates that intestinal dysbiosis triggers a mucosal immune response that stimulates T and B cells, which are critical to the development of inflammatory arthritis…

A Defect in Mitochondrial Function May Underlie Chronic Fatigue Syndrome

Lara C. Pullen, PhD  |  January 1, 2018

The peripheral blood mononuclear cells (PBMCs) of patients with chronic fatigue syndrome (CFS) may be unable to meet certain energetic demands, according to a U.K. study. Researchers found that PBMCs in healthy individuals may adapt to environmental stressors by enhancing their ability to increase ATP production through mitochondrial respiration, but not in patients with CFS…

Some Jobs Tied to Higher Risk of RA

Lisa Rapaport  |  August 18, 2017

(Reuters Health)—Workers exposed to airborne toxins may have an elevated risk of developing rheumatoid arthritis (RA), an immune system disorder that causes debilitating swelling and pain in the joints, a Swedish study suggests. Among men, bricklayers, concrete workers and electricians had at least twice the risk of RA they would have in certain other occupations,…

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