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Articles tagged with "monotherapy"

Risk of Adverse Outcomes Due to COVID-19 May Be Lower with TNF Inhibitor Monotherapy

Katie Robinson  |  May 5, 2022

Findings support the continued use of TNF inhibitor monotherapy in individuals with immune-mediated inflammatory diseases. In the study, these patients had a lower risk of hospitalization or death caused by COVID-19 than patients on other commonly prescribed treatment regimens

Efficacy of Tocilizumab Monotherapy After Ultra-Short Glucocorticoid Administration in GCA

Michele B. Kaufman, PharmD, BCGP  |  July 27, 2021

In a small study, patients with GCA maintained remission after receiving three days of treatment with methylprednisolone followed by tocilizumab.

Research Outlines Benefits of bDMARDs to Treat Early RA

Michele B. Kaufman, PharmD, BCGP  |  February 10, 2021

Sapart et al. suggest a combination of methotrexate and biologic disease-modifying anti-rheumatic drugs as induction therapy for patients with early RA may lead to long-term remission.

RA Patients Taking Either 15 mg or 30 mg Dose of Upadacitinib Experience Improvement

Arthritis & Rheumatology  |  October 1, 2020

The SELECT-EARLY MTX-controlled trial examined the safety and efficacy of upadacitinib, a potent, reversible jakinib, as monotherapy in patients with moderately to highly active RA and poor prognostic features who are either naive for or have limited exposure to methotrexate.

RA Patients May Safely Stop Methotrexate in Tofacitinib Combination Therapy

Michele B. Kaufman, PharmD, BCGP  |  July 29, 2019

RA patients who achieve low disease activity on tofacitinib and methotrexate combination therapy can safely cease methotrexate use, according to recent research…

Upadacitinib Monotherapy Proves Promising; Plus FDA Approves Tocilizumab Autoinjector

Michele B. Kaufman, PharmD, BCGP  |  December 10, 2018

In a study, RA patients taking upadactinib monotherapy experienced less pain and morning joint stiffness than methotrexate-treated patients…

Tocilizumab Monotherapy May Sustain Low Disease Activity in RA Patients

Michele B. Kaufman, PharmD, BCGP  |  December 15, 2017

New research demonstrates that subcutaneous tocilizumab monotherapy may preserve disease control in RA patients who have discontinued methotrexate…

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