Researchers suspect the C-type lectin receptor (CLR) mincle may play a role in experimental autoimmune uveoretinitis. A new study linked CLR mincle to Card9-signaling events and IL-1, resulting in inflammation…
Mycophenolate Sodium Effective for Chronic Noninfectious Pediatric Uveitis
NEW YORK (Reuters Health)—Mycophenolate sodium (MPS) is effective for treating children with chronic noninfectious uveitis, researchers from Germany report. “Mycophenolate sodium could be used as a preferred steroid-sparing agent in children with chronic noninfectious intermediate uveitis,” Dr. Deshka Doycheva, from the University of Tuebingen, Germany, told Reuters Health by email. MPS is an enteric-coated formulation…
Rituximab May Benefit Patients with Refractory JIA-Associated Uveitis
NEW YORK (Reuters Health)—Rituximab may calm juvenile idiopathic arthritis (JIA)-associated uveitis and especially benefit patients who haven’t responded to other biologic treatments, a study from Italy suggests. With its convenient dosing schedule, rituximab may be a new treatment option for patients with autoimmune diseases, especially for those who have not responded to tumor necrosis factor…
Gut Microbes Activate T Cells Causing Autoimmune Eye Disease
NEW YORK (Reuters Health)—Commensal microbes in the gut can activate retina-specific T cells that go on to cause autoimmune uveitis in a mouse model, researchers report. “These findings allow us to understand the biological basis for the disease,” lead author of the study, Dr. Rachel Caspi from National Eye Institute at the NIH in Bethesda,…
Psoriatic Disease Linked to Higher Risk of Uveitis & Vice Versa
NEW YORK (Reuters Health)—Two classes of inflammatory diseases, uveitis and psoriatic disease, appear linked, as a diagnosis of one increases the risk of developing the other, new research has found. A study of Danish patient registries found nearly triple the rate of uveitis among patients with psoriatic arthritis compared to the general population, and double…
2013 ACR/ARHP Annual Meeting: Inflammatory Eye Disease Management Can Benefit from Collaboration between Rheumatologists and Ophthalmologists
Joint effort is critical to diagnosing and treating uveitis, iritis, and other autoimmune eye disorders in patients with inflammatory disease
Aggressive Treatment of Inflammation Prevents Vision Loss in Patients with JIA-related Uveitis
A new study confirms that the use of immunosuppressive drugs is associated with a reduced risk of vision loss in patients with juvenile idiopathic arthritis-related uveitis.
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