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You are here: Home / Search for "allopurinol"

Search results for: allopurinol

Allopurinol for Gout an Unlikely Contributor to Kidney Disease

October 8, 2018 • By Reuters Staff

NEW YORK (Reuters Health)—Allopurinol does not appear to contribute to decline in kidney function and may actually protect renal function in patients with gout, according to a large population-based study. Gout affects around 4% of Americans and often occurs alongside chronic kidney disease (CKD), Dr. Tuhina Neogi from Boston University School of Medicine and colleagues… [Read More]

Filed Under: Conditions, Crystal Arthritis Tagged With: Allopurinol, chronic kidney disease, Gout, kidney

FDA Approves Lesinurad + Allopurinol

September 19, 2017 • By Michele B. Kaufman, PharmD, BCGP

Duzallo, a combination of lesinurad and allopurinol, was approved by the FDA in August to treat hyperuricemia associated with gout…... [Read More]

Filed Under: Drug Updates Tagged With: Allopurinol, Duzallo, FDA, Food and Drug Administration, Gout, hyperuricemia, lesinurad, U.S. Food and Drug Administration

Allopurinol Appears More Renoprotective than Febuxostat in Older Adults

July 20, 2017 • By Reuters Staff

NEW YORK (Reuters Health)—The renal protective effect of allopurinol appears to differ from that of febuxostat in the elderly, according to new research. The study, of a nationally representative sample of Medicare patients, showed that allopurinol was associated with a greater reduction in the risk of incident kidney disease, report the authors online July 13… [Read More]

Filed Under: Conditions, Drug Updates Tagged With: Allopurinol, Febuxostat, kidney disease, Medicare patients, renal protective effect

Lesinurad with Allopurinol When Allopurinol Alone Is Insufficient

December 29, 2016 • By Arthritis & Rheumatology

Current guidelines for the long-term management of gout recommend a combination of lifestyle management and/or pharmacotherapy to lower serum UA levels to <6.0 mg/dL in most patients or <5.0 mg/dL in patients with more severe disease. Allopurinol is the most widely used xanthine oxidase inhibitor and is recommended in treatment guidelines as a first-line urate-lowering… [Read More]

Filed Under: Conditions, Crystal Arthritis Tagged With: Allopurinol, Arthritis & Rheumatology, Gout, lesinurad, Uric acid

Blacks, Asians at Higher Risk for Allopurinol-Related Skin Reactions

September 8, 2016 • By Deborah Levenson

Be careful when prescribing allo­purinol to black and Asian gout patients, a study newly advises. Black and Asian patients who take this ubiquitous, more-than-40-year-old medication are at much higher risk of certain serious skin reactions than are Caucasians or Hispanics. Compared with Caucasians, blacks who take allopurinol to lower blood urate levels have an increased… [Read More]

Filed Under: Conditions, Drug Updates Tagged With: Allopurinol, Asian, black, Gout, outcome, patient care, rheumatologist, risk, skin reaction, Treatment, Uric acid

Gout Experts Share Insights Into a Variety of Challenging Gout Scenarios

June 14, 2022 • By Ruth Jessen Hickman, MD

Although the diagnosis and treatment of gout are sometimes straightforward, prac­titioners encounter challenges in patients with atypical presentations, as well as those with medically complex situations or refractory disease. Here, gout experts share insights into some of these scenarios. Flare in Hospitalized Patients When not contraindicated, the 2020 ACR Guideline for the Management of Gout… [Read More]

Filed Under: Conditions, Crystal Arthritis Tagged With: Flares, Gout Resource Center, organ transplant, pegloticase, polyarticular arthritis, refractory gout

ACR Image Competition 2021 Results, Part 3: Erosive Polyarticular Tophaceous Gout

May 12, 2022 • By Wendy Wan Hui Lee, MD, MRCP(UK); FEATURED IMAGE FROM EAST ASIA & PACIFIC

A 27-year-old man was referred to us for joint pain and nodular swelling over multiple joints. His symptoms started when he was 13 years old, but he was sub-optimally treated. On examination, we found marked digital deformity, with multiple large tophi over the small joints of his hands, elbows, knees and both feet. Hand radiographs… [Read More]

Filed Under: Professional Topics Tagged With: bias, Diversity, healthcare disparities, Image Competition, Racism

Case Report: Lipoma Arborescens of the Knee

May 12, 2022 • By John Nawrocki, MD, Kevin Hess, DO, & Maryah Mansoor, MBBS

Lipoma arborescens is a rare, benign intra-articular lesion characterized by diffuse replacement of synovial tissue by mature adipocytes, causing a villous lipomatous proliferation of the synovial membrane.1 Typically, this is a mono­articular condition, with the knee being the most commonly affected although it has been rarely reported to occur in an oligo-/polyarticular fashion and in… [Read More]

Filed Under: Conditions, Crystal Arthritis Tagged With: case report, Gout, Gout Resource Center, knee pain, lipoma arborescens

Research Roundup: Abstract Data Presented at ACR Convergence 2021

February 11, 2022 • By Keri Losavio

The research presented at ACR Convergence 2021 had a broad scope. Below are details on three studies that addressed cardiovascular safety in treat-to-target strategies, phase 2 study results on the efficacy of tigulixostat and the impact of patient preference on treatment adherence. Refer to the ACR meeting abstracts for full details on all of the… [Read More]

Filed Under: ACR Convergence, Conditions, Crystal Arthritis, Patient Perspective, Research Reviews Tagged With: ACR Convergence – Gout, ACR Convergence 2021 – Gout, Gout, tigulixostat, Treat-to-Target

Gout Management Recommendations from the ACR’s 2020 Guideline

February 11, 2022 • By From the College

The 2020 ACR Guideline for the Management of Gout is intended to provide guidance for the management of patients with gout, and includes recommendations on the indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations.1 The guideline includes 42 recommendations, of which 16 are strong…. [Read More]

Filed Under: Conditions, Crystal Arthritis, Guidelines Tagged With: Gout, Gout Resource Center

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