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Search results for: central nervous system

Case Report: Amyloid Beta-Related Angiitis of the Central Nervous System

Alexandros Grivas, MD, Nikil Revuri, MD, Aleksandra Karaseva, MD, Basimah AlBalooshy, MD, & Andres M. Ponce, MD  |  October 8, 2024

Here, we present a case of inflammatory cerebral amyloid angiopathy, discussing its diverse clinical manifestations, diagnostic challenges in view of recently proposed clinical-radiologic criteria and its management.

Filed under:ConditionsOther Rheumatic ConditionsVasculitis Tagged with:amyloid β-related angiitiscase reportcentral nervous system vasculitiscerebral amyloid angiopathy

7 Key Insights Into the Evaluation of Central Nervous System Vasculitis

Jason Liebowitz, MD, FACR  |  May 13, 2021

Many a rheumatology consult has centered on a perplexing question: Does this patient have central nervous system (CNS) vasculitis? At the 2021 ACR State-of-the-Art Clinical Symposium, Rula Hajj-Ali, MD, FACP, professor of medicine and associate director of vasculitis care and research, Cleveland Clinic Lerner College of Medicine, discussed this topic in detail, providing a series…

Filed under:ConditionsMeeting ReportsVasculitis Tagged with:2021 State of the Art Clinical Symposiumcentral nervous systemcentral nervous system vasculitis

Case Report: Lymphocytic Vasculitis of the Central Nervous System

Gbemisola Olayemi, MD, Evangeline Scopelitis, MD, & Jerald M. Zakem, MD  |  January 17, 2019

Vasculitis is a group of chronic inflammatory diseases in which the blood vessel is the target of an immune reaction. They can be secondary to connective tissue disease, idiopathic or due to infection, neoplasm or drugs.1 Primary angiitis of the central nervous system (PACNS) is a rare syndrome characterized by inflammatory cell infiltration and necrosis…

Filed under:ConditionsVasculitis Tagged with:central nervous system vasculitiscyclophosphamideMethylprednisolonePrimary Angiitis of the Central Nervous System

Rheumatic Disease Manifestations in the Central Nervous System

Thomas R. Collins  |  January 19, 2016

SAN FRANCISCO—Let’s say your radiologist comes to you and says that an angiogram gives a diagnosis of CNS vasculitis on four patients, all with acute onset of headache and stroke: One is a 25-year-old woman who is three months pregnant. Another is a 50-year-old man using excessive doses of nasal decongestants. Another is a 40-year-old…

Filed under:ConditionsMeeting ReportsResearch Rheum Tagged with:angiitiscentral nervous systempatient careResearchRheumatic Diseaserheumatologysymptom

Rheumatology Case Report: When Moyamoya Disease Mimicks Primary Central Nervous System Vasculitis

Joey Kim, MD, Megha Patel-Banker, MD, Matthew Abramson, MD, Mehwish Bilal, MD, Sanjay Godhwani, MD, Asha Patnaik, MD, Heidi Roppelt, MD, & Qingping Yao, MD  |  November 16, 2015

Case report: A 60-year-old Hispanic male with poorly controlled hypertension was sent from the primary care clinic for evaluation of malignant hypertension with a systolic blood pressure above 200 mmHg. His symptoms at the time of presentation included episodic confusion, worsening vision and an unsteady gait. A head computed tomography (CT) scan showed a subacute…

Filed under:ConditionsVasculitis Tagged with:case reportcentral nervous systemDiagnosismoyamoyapatient carerheumatologyTreatmentVasculitis

2014 ACR/ARHP Annual Meeting: Diagnosis, Management of Sarcoidosis in the Heart, Central Nervous System

Kathy Holliman  |  March 1, 2015

Without reliable diagnostic tests or evidence-based treatment guidelines, patient symptoms critical to diagnosing disease

Filed under:ConditionsMeeting ReportsOther Rheumatic Conditions Tagged with:ACR/ARHP Annual Meetingcentral nervous systemDiagnosisheartHollimanrheumatologySarcoidosis

Representation of the molecular structure of interferon a.

Interferons in Systemic Lupus Erythematosus

Katie Robinson  |  March 21, 2024

Current knowledge of receptor-ligand interactions, cell signaling, and transcriptional regulation derive from studies of type I interferon. The design of novel therapeutics is informed by the advances in investigation of type I interferon, with the potential for important impacts on patient management.

Filed under:American College of RheumatologyConditionsResearch ReviewsResearch RheumSystemic Lupus Erythematosus Tagged with:Arthritis & RheumatologyImmunologyinterferon

Management Updates for a Spectrum of Systemic Autoinflammatory Diseases

Ruth Jessen Hickman, MD  |  January 19, 2024

SAN DIEGO—As part of a panel on systemic autoinflammatory diseases (SAIDs) at a Nov. 15 scientific session of ACR Convergence 2023, Sivia Lapidus, MD, shared context and insights on the therapeutic management of patients with these conditions. The Spectrum of SAIDs SAIDs encompass a broad swath of individually rare disorders driven by innate immune responses…

Filed under:ACR ConvergenceConditionsMeeting ReportsOther Rheumatic Conditions Tagged with:ACR Convergence 2023CAPSCOVID-19Familial Mediterranean feverPFAPATRAPS

Studies Examine Peripheral Nervous System Disease in Lupus Patients

Linda Childers  |  November 12, 2020

Although systemic lupus erythematosus (SLE) affects both the central nervous system (CNS) and peripheral nervous system (PNS), past research has primarily focused on how lupus affects the CNS. Now, an international, inception cohort study, “Peripheral Nervous System Disease in Systemic Lupus Erythematosus,” published in Arthritis & Rheumatology, has examined different types of PNS disease to…

Filed under:ConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:central nervous systemperipheral nervous systemquality of life

A Historical Look at the Characterization of Lupus as a Systemic Disease

Ruth Jessen Hickman, MD  |  October 18, 2018

The disease called systemic lupus erythematosus (SLE) went through many different stages of classification before reaching the modern criteria reflecting our current understanding of its pathogenesis. In 1872, the Viennese dermatologist Moriz Kaposi, MD, published a paper, “New Contributions to Knowledge of Lupus Erythematosus,” which provided a significant leap forward in the characterization of this…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:Classification CriteriaDr. Moriz KaposiHistoryLost & Found

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