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Big Data May Shift Reference Ranges for Some Lab Tests

  |  Issue: October 2018  |  

Susan Bernstein is a freelance medical journalist based in Atlanta.

References

  1. Manrai AK, Patel CJ, Ioannidis JPA. In the era of precision medicine and big data, who is normal? JAMA. 2018 May 15;319(19):1981–1982.
  2. Lacy ME, Wellenius GA, Sumner AE. Association of sickle cell trait with hemoglobin A1c in African Americans. JAMA. 2017 Feb 7;317(5):507–515.
  3. Horowitz GL, Altaie S, Boyd JC, et al. EP28-A3C: Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory, 3rd Edition. CLSI, 2010.

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