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You are here: Home / Articles / Challenging Cases in Osteoporosis: Tips from an Expert

Challenging Cases in Osteoporosis: Tips from an Expert

June 18, 2022 • By Samantha C. Shapiro, MD

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Samantha C. Shapiro, MD, is an academic rheumatologist and an affiliate faculty member of the Dell Medical School at the University of Texas at Austin. She received her training in internal medicine and rheumatology at Johns Hopkins University, Baltimore. She is also a member of the ACR Insurance Subcommittee.

References

  1. Stevenson JC. Bisphosphonates and atypical femoral shaft fractures. N Engl J Med. 2011 Jul 28;365(4):377; author reply 377.
  2. Schilcher J, Michaëlsson K, Aspenberg P. Bisphosphonate use and atypical fractures of the femoral shaft. N Engl J Med. 2011 May 5;364(18):1728–1737.
  3. Black DM, Geiger EJ, Eastell R, et al. Atypical femur fracture risk versus fragility fracture prevention with bisphosphonates. N Engl J Med. 2020 Aug 20;383(8):743–753.
  4. Curtis JR, Saag KG, Arora T, et al. Duration of bisphosphonate drug holidays and associated fracture risk. Med Care. 2020 May;58(5):419–426.
  5. Adler RA, El-Hajj Fuleihan G, Bauer DC, et al. Managing osteoporosis in patients on long-term bisphosphonate treatment: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016 Jan;31(1):16–35.
  6. Kendler DL, Marin F, Zerbini CAF, et al. Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): A multicentre, double-blind, double-dummy, randomised controlled trial. Lancet. 2018 Jan 20;391(10117):230–240.
  7. Cosman F, Crittenden DB, Adachi JD, et al. Romosozumab treatment in postmenopausal women with osteoporosis. N Engl J Med. 2016 Oct 20;375(16):1532–1543.
  8. McClung MR, Grauer A, Boonen S, et al. Romosozumab in postmenopausal women with low bone mineral density. N Engl J Med. 2014 Jan 30;370(5):412–420.
  9. Saag KG, Petersen J, Brandi ML, et al. Romosozumab or alendronate for fracture prevention in women with osteoporosis. N Engl J Med. 2017 Oct 12;377(15):1417–1427.

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Filed Under: Conditions, Education & Training, Meeting Reports Tagged With: ACR Education Exchange, bisphosphonates, denosumab, education and training, Osteoporosis, romosozumabIssue: July 2022

You Might Also Like:
  • Amgen, UCB Say Osteoporosis Drug Meets Main Goal in Late-Stage Trial
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  • At Least 1 Year on Bisphosphonates Needed for Fracture Prevention
  • A Balancing Act: Tips to Ensure Optimal Screening & Treatment for Osteoporosis

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