The authors conclude by emphasizing the common regulatory mechanisms governing de- and redifferentiation transitions in cartilage and tendon cells. They also note that, in its totality, their research provides testable networks that can be used for future analyses of sustained or directed differentiation of cartilage and tendon.
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Lara C. Pullen, PhD, is a medical writer based in the Chicago area.
- Mueller AJ, Tew SR, Vasieva O, et al. A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes. Sci Rep. 2016 Sep 27;6:33956. doi: 10.1038/srep33956.