Certolizumab pegol is now FDA approved to treat adults with active non-radiographic axial spondyloarthritis…
Anti-Mitochondrial Antibodies & Systemic Lupus Erythematosus
Although antimitochondrial antibodies are present in SLE patients, researchers have has difficulty investigating the phenomenon due to barriers in isolating pure mitochondria. The study describes a technique that allows for such an investigation and provides insight into how the adaptive immune system recognizes mitochondrial organelles…
Lori Gilbert-Kaye Killed, 3 Others Injured in California Synagogue Shooting
The ACR is greatly saddened by the loss of Lori Gilbert-Kaye, wife of rheumatologist Howard Kaye, MD. Mrs. Gilbert-Kaye was tragically killed in the San Diego-area synagogue shooting on April 27 after she dove in front of Rabbi Yisroel Goldstein, saving his life. We send our deepest condolences to Dr. Kaye and his family. CNN…
Osteoporotic Fracture Rates Similar with Denosumab, Alendronate in Real World
NEW YORK (Reuters Health)—Rates of osteoporotic fracture were similar three years after starting either denosumab or alendronate in a real-world Danish population-based cohort study. “Previous studies have shown that denosumab is more efficacious than alendronate in increasing bone mineral density (BMD), possibly the best proxy outcome for subsequent fracture risk. However, previous studies were underpowered…
FDA Approves New Osteoporosis Medication
Romosozumab-aqqg has been approved in the U.S. for treating postmenopausal women with osteoporosis at high risk of fracture…
Parent-Child Reminiscing Affects Children’s Pain Memories
NEW YORK (Reuters Health)—How parents and children reminisce about the child’s recent surgery affects the child’s pain memory, researchers from Canada report. Children who recall pain that is higher than initially reported are more likely to report more pain and distress during future pain experiences. These negatively biased memories, formed early in life, set the…
IBD Patients Who Switch from Infliximab to Biosimilar See Mixed Results
NEW YORK (Reuters Health)—Patients with inflammatory bowel disease (IBD) can safely switch from infliximab to the biosimilar CT-P13, though they may face a higher risk of clinical relapse, researchers from Spain report. Recent studies have demonstrated the effectiveness and safety of infliximab biosimilars in patients with IBD, but there are limited data about the effectiveness…
Gout & Sexual Function
Pain, physical disability and joint deformity have been linked to sexual dysfunction. New research suggests gout may also significantly affect relationships and intimacy. The study found the physical effects of gout on intimacy, such as joint pain, were the top-ranked concern for gout patients…
Dr. Shervin Assassi: New Chair of the ACR Committee on Journal Publications
Shervin Assassi, MD, MS, was the child of two physicians. His mother practiced obstetrics, and his father was a trauma surgeon. It gave him an appreciation for the hard work that goes into medicine and a fascination for joints. He developed an interest in immunology while in medical school. “It was natural for me to…
First-Year Medical Residents Spend Little Time on Patient Care
(Reuters Health)—Over a typical 24-hour shift, first year residents training in internal medicine spend just three hours on direct patient care and only 1.8 hours on education, a U.S. study suggests. Most of their time—an average of 15.9 hours out of every 24-hour shift—is consumed instead by “indirect patient care,” primarily involving interactions with medical…
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