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TNF-α Impairs Regulatory T Cells in Patients with Rheumatoid Arthritis

Lara C. Pullen, PhD  |  June 3, 2013

When researchers treated patients with RA with TNF-α–specific antibody, they were able to restore Treg cell function. (posted June 3, 2013)

Salt as a Promoter of Th17 Cells and Autoimmune Disease

Lara C. Pullen, PhD  |  May 21, 2013

New research on Th17 suggests that a high salt diet may be a risk factor for inflammation.

Will New Rheumatoid Arthritis Blood Test Improve Early Diagnosis?

Richard Quinn  |  May 6, 2013

Two new blood tests may boost the accuracy of RA diagnose, although more data needed. (posted May 5, 2013)

Steroid Injections for Lateral Epicondylalgia Worse than Placebo in Long Term

Jeffrey A. Sparks, MD  |  May 3, 2013

In a recent study of unilateral lateral epicondylalgia, corticosteroid injection resulted in worse clinical outcomes compared to placebo injection, and there were no significant differences in those who received physical therapy or no physical therapy.

Chondrocyte Enlargement Sheds New Light on Cell Volume Regulation

Lara C. Pullen, PhD  |  May 2, 2013

New research describes the regulation of skeletal size and explores how cells sense, modify, and establish a volume set point.

Large Genome Study Identifies Genetic Risk Factors for Gout

Lara C. Pullen, PhD  |  April 26, 2013

Researchers have identified 28 genome-wide significant urate concentration–associated loci, underscoring the importance of metabolic control in urate production.

Susceptibility Loci Shed Light on Fundamental Pathways of Psoriasis

Lara C. Pullen, PhD  |  April 26, 2013

Investigators have described 15 new psoriasis susceptibility loci. The loci highlight the importance of the skin in both acquired and innate host defense and identify the innate immune response as a key factor in psoriasis.

Sequester Affects Rheumatologists on Two Fronts—Medicare Reimbursement and Research Funding

Richard Quinn  |  April 18, 2013

Rheumatologists are already feeling two effects from Congress’ inability to solve sequestration: a 2% reduction in Medicare reimbursements and slashed funding for research financed by the National Institutes of Health.

DNA Methylation Modifies Genetic Risk for Rheumatoid Arthritis

Lara C. Pullen, PhD  |  April 12, 2013

A first-of-its-kind study has been published that integrates genotype and epigenotype data across the entire genome.

ABIM Announces New Rules, Timelines for Maintenance of Certification

Michael O’Neal  |  April 8, 2013

The ABIM recently announced that, beginning in January 2014, all physicians certified during or after 1990 (time-limited certificates) will be required to complete 100 maintenance of certification points every five years, as opposed to the previous ten-year timeline.

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