NEW YORK (Reuters Health)—Screening for celiac disease (CD) is important in patients newly diagnosed with type 1 diabetes (T1D) and in children presenting for rheumatology evaluation, according to a pair of new reports.
In a systematic review, online June 15 in Pediatrics, Australian researchers found most cases of CD are diagnosed within five years of T1D diagnosis; therefore, screening should be considered at T1D diagnosis and within two and five years thereafter, they advise.
Dr. Maria Craig from the Institute of Endocrinology and Diabetes, The Children’s Hospital of Westmead, New South Wales, and colleagues note that the association between T1D and CD is well documented in young people, although reported rates vary from about 2% to 16%. And screening guidelines are “variable and not evidence based.”
They reviewed nine longitudinal cohort studies involving 11,157 children and adolescents with T1D, of whom 587 had biopsy-proven CD. The prevalence of CD varied from 1.6% to 9.7%, with a weighted pooled prevalence of 5.1%.
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