Kidney involvement is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE). Collectively termed lupus nephritis, SLE with kidney involvement comes in many subtypes. The current classification by the International Society of Nephrology/Renal Pathology Society (ISN/RPS), however, does not include lupus podocytopathy, which, through various clinical and epidemiologic studies, has recently been…
In 2022, an international group of researchers reported the seminal finding that a gain-of-function variant of a single-stranded ribonucleic acid (RNA) sensor, known as toll-like receptor 7 (TLR7), can cause human systemic lupus erythematosus (SLE).1 The paper in Nature showed that a newly described variant of TLR7, identified in a child with severe lupus, was…
Howard Schubiner, MD, shares what led him to focus on the mind-body connection during an episode of the ACR on Air podcast. He discusses recent research into how pain reprocessing may help patients suffering from psychological-related chronic pain.
Effective July 5, discrimination based on race, color, national origin, sex, age and disability by healthcare programs receiving federal assistance is once again prohibited. The application of Section 1557 to all HHS health programs and activities and state and federally facilitated exchanges, which had been weakened by the Trump administration, has been reinstated.
Hoy et al. sought to evaluate the presence, clinical associations, and potential mechanistic roles of circulating calprotectin in a cohort of patients with primary antiphospholipid syndrome (APS) and those with antiphospholipid antibodies. Calprotectin levels were higher in patients with primary APS and those with antiphospholipid antibodies than in healthy controls. These data suggest that calprotectin has the potential to be a functional biomarker and a new therapeutic target for APS-related thrombocytopenia.
The ACR will lead five other specialty societies on a resolution supporting pediatric specialty care and will co-lead resolutions addressing Medicare Advantage Part B drug coverage, white bagging mandates, state prescription drug affordability boards and impacts of alternative funding programs on access to care.
On May 6–7, nearly 100 rheumatologists and rheumatology professionals converged in Washington, D.C., for the ACR’s annual Advocacy Leadership Conference and 137 meetings on Capitol Hill. You can help extend the efforts of these advocates and amplify their impact by contacting your lawmakers via the Legislative Action Center.
Don’t reinvent the wheel. The ACR Committee on Rheumatologic Care offers members an updated slate of template letters to help appeal insurance denials for common off-label rheumatology treatments.
A survey in June, led by the AMA but endorsed by the ACR, will collect data on practice costs and hours of patient care. Practices selected to participate will be contacted via email and U.S. Postal Service, and are encouraged to respond.
Solomon et al. examined whether a mobile application (app) for patients with rheumatoid arthritis integrated in the electronic health record would be used by patients and rheumatologists.