Joseph Holoshitz, MD, and his laboratory have made significant advances in understanding a genetic risk factor of rheumatoid arthritis (RA). This knowledge has grown into discoveries that could lead to new RA treatments in just a few years. “There was a critical point in time when we had a big idea, but funding was a…
The ACR’s Volunteer Leaders Can Help Shape Rheumatology’s Future
Margaret Mead, an early 20th century anthropologist, said, “Never believe that a few caring people can’t change the world. For, indeed, that’s all who ever have.”1 The mission of the American College of Rheumatology is Advancing Rheumatology!, and it cannot be achieved without the time, effort, talent and experience of volunteer leaders. You can join…
Oxidized Mitochondrial DNA May Contribute to Inflammation in SLE
New research examines how the generation of reactive oxygen species and neutrophil extracellular traps may break down the protective mechanisms of mitochondrial DNA, resulting in NETosis in people with autoimmune disease. They found oxidized mitochondrial DNA may contribute to inflammation in such diseases as systemic lupus erythematosus by upregulating type I interferon signatures…
Women Lag Men as Lead Authors in Top Medical Journals
(Reuters Health)—Women are more apt to be lead authors of research in major medical journals today than they were a generation ago, but they still lag significantly behind men, a recent study suggests. The gender gap matters because lead authors make key decisions on what topics to research, who to include in studies, which outcomes…
From the Expert: New Insights into Treating Pregnant Patients with Rheumatic Disease
The approach of under-treating rheumatic disease in pregnant patients is changing, according to Bonnie Lee Bermas, MD. Dr. Bermas discusses with The Rheumatologist the need for more research on how drugs affect this patient group, and how timing of conception and disease stability play important roles in the safe outcomes of mother and infant…
U.S. Health Agency Estimates 2015 Prescription Drug Spending Rose to $457 Billion
NEW YORK (Reuters)—Spending on prescription drugs is projected to have risen to $457 billion in 2015 and will likely continue to grow as a percentage of overall healthcare spending, a U.S. government health agency said on Tuesday. That is an increase of about 8% from 2014’s prescription drug spending, which is also an estimated figure,…
Health Apps Often Lack Privacy Policies & Share Our Data
(Reuters Health)—Just because a health app has a privacy policy doesn’t mean the data will remain private, an analysis of mobile tools for diabetes suggests. In fact, privacy policies appear rare, and when they do exist, most state that user data will be collected and half warn that medical information will be shared with third…
The ACR Announces Research Agenda for 2016–2020
Future rheumatology-specific research should focus on the definition of new therapeutic targets, improving the understanding of existing therapies, engaging patients in their care and more, according to a recent assessment by the ACR’s Committee on Research…
The ACR Addresses the FDA about the Safe Adoption of Biosimilars in the U.S.; Plus Tofacitinib Approved for RA & Romosozumab May Reduce Fracture Risk
The ACR has continued its advocacy to ensure the safe adoption of biosimilars in the U.S., most recently addressing an FDA public hearing. Also, the FDA has approved tofacitinib for RA, and a clinical trial of romosozumab for patients with osteoporosis met its primary endpoint…
Routine Osteoporosis Screening in Men Proves Cost-Effective
NEW YORK (Reuters Health)—Routine osteoporosis screening in men is a good value and effective based on a cost-effectiveness model, researchers say. “Osteoporosis is not just a disease for women. Osteoporosis affects many men (approximately 2 million in the U.S.), with significant morbidity, mortality, and costs that are projected to rise with the aging of the…
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