Systemic autoimmune diseases are thought to result from immune dysregulation in genetically susceptible individuals who were exposed to environmental risk factors. Many studies have identified genetic risk factors for these diseases, but concordance rates among monozygotic twins are 25–40%, suggesting that nonheritable environmental factors play a more prominent role.1,2 Through carefully conducted epidemiologic and other…
In 2004, Stacy Ardoin, MD, MHS, became pregnant with twins during the second year of her fellowship at Duke University School of Medicine, Durham, N.C. Although she and her husband, Adrien, were thrilled by the news, the astronomical cost of day care for two infants was a specter. At the time, Adrien managed a bookstore…
How to recognize distinctions between pediatric and adult arthritis
The transition from pediatric to adult care can be a rocky one. For many rheumatology patients, any problems in the move can cause gaps in care. To address this issue, the ACR joined the American College of Physicians’ (ACP) Pediatric to Adult Care Transitions Initiative. The Initiative is a project spearheaded by the ACP’s Council…