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Prednisone Might be the Missing Ingredient in the American College of Rheumatology’s Recommendations for Treating Patients with Rheumatoid Arthritis

John Kirwan, MD  |  Issue: April 2013  |  April 1, 2013


Dr. Kirwan is professor of rheumatic diseases at the University of Bristol and consultant rheumatologist at the University Hospitals Bristol NHS Foundation Trust, both in the U.K.

References

  1. Kersley GD. Amethopterin (methotrexate) in connective tissue disease-psoriasis and polyarthritis. Ann Rheum Dis. 1968;27:64-66.
  2. Hench PS, Kendall EC, Slocumb CH, Polley HF. Effects of a hormone of the adrenal cortex (17-hydroxy-11 dehydrocorticosterone: compound E) and of pituitary adrenocorticotrophic hormone on rheumatoid arthritis: Preliminary report. Proc Staff Meet Mayo Clin. 1949;24:181-197.
  3. Hench PS, Kendall EC, Slocumb CH, et al. Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions. Arch Intern Med. 1950;85:545-666.
  4. Pincus T, Marcum SB, Callahan LF. Long-term drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone. J Rheumatol. 1992;19:1885-1894.
  5. Kirwan JR. The origins, results and consequences of the 1995 Arthritis Research Campaign Low-dose Glucocorticoid Study. Clin Exp Rheum. 2011; 29(Suppl. 68):S52-S58.
  6. Kirwan JR, Bijlsma JWJ, Boers M, Shea BJ. Effects of glucocorticoids on radiological progression in rheumatoid arthritis. Cochrane Database of Systematic Reviews, 2007;1:CD006356.
  7. Singh JA, Furst DE, Bharat A, et al. 2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012;64:625-639.
  8. Kirwan JR. Combination therapy including glucocorticoids: The new gold standard for early treatment in rheumatoid arthritis? Ann Intern Med. 2012;156:390-391.

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Filed under:ConditionsDrug UpdatesRheumatoid Arthritis Tagged with:AC&RGlucocorticoidsprednisoneRARheumatoid arthritisSteroid

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