A limitation of the study is that follow-up time and statistical power are “inherently limited to less than 10 years,” given the relatively recent introduction of non-TNF inhibitor therapy in RA.
Despite this, they say it can be concluded from this study that “short-to medium-term use of tocilizumab, abatacept, rituximab, or anti-TNF drugs seems to be safe with regard to risks of incident cancer.”
- Wadström H, Frisell T, Askling J, et al. Malignant Neoplasms in Patients With Rheumatoid Arthritis Treated With Tumor Necrosis Factor Inhibitors, Tocilizumab, Abatacept, or Rituximab in Clinical Practice: A Nationwide Cohort Study From Sweden. JAMA Intern Med. 2017 Sept 18. [Epub ahead of print]