The Rheumatologist
COVID-19 NewsACR Convergence
  • Connect with us:
  • Facebook
  • Twitter
  • LinkedIn
  • YouTube
  • Feed
  • Home
  • Conditions
    • Rheumatoid Arthritis
    • SLE (Lupus)
    • Crystal Arthritis
      • Gout Resource Center
    • Spondyloarthritis
    • Osteoarthritis
    • Soft Tissue Pain
    • Scleroderma
    • Vasculitis
    • Systemic Inflammatory Syndromes
    • Guidelines
  • Resource Centers
    • Axial Spondyloarthritis Resource Center
    • Gout Resource Center
    • Psoriatic Arthritis Resource Center
    • Rheumatoid Arthritis Resource Center
    • Systemic Lupus Erythematosus Resource Center
  • Drug Updates
    • Biologics & Biosimilars
    • DMARDs & Immunosuppressives
    • Topical Drugs
    • Analgesics
    • Safety
    • Pharma Co. News
  • Professional Topics
    • Ethics
    • Legal
    • Legislation & Advocacy
    • Career Development
      • Certification
      • Education & Training
    • Awards
    • Profiles
    • President’s Perspective
    • Rheuminations
    • Interprofessional Perspective
  • Practice Management
    • Billing/Coding
    • Quality Assurance/Improvement
    • Workforce
    • Facility
    • Patient Perspective
    • Electronic Health Records
    • Apps
    • Information Technology
    • From the College
    • Multimedia
      • Audio
      • Video
  • Resources
    • Issue Archives
    • ACR Convergence
      • Gout Resource Center
      • Axial Spondyloarthritis Resource Center
      • Psoriatic Arthritis
      • Abstracts
      • Meeting Reports
      • ACR Convergence Home
    • American College of Rheumatology
    • ACR ExamRheum
    • Research Reviews
    • ACR Journals
      • Arthritis & Rheumatology
      • Arthritis Care & Research
      • ACR Open Rheumatology
    • Rheumatology Image Library
    • Treatment Guidelines
    • Rheumatology Research Foundation
    • Events
  • About Us
    • Mission/Vision
    • Meet the Authors
    • Meet the Editors
    • Contribute to The Rheumatologist
    • Subscription
    • Contact
  • Advertise
  • Search
You are here: Home / Articles / Study Finds an Indirect Association Between Sleep & Inflammation

Study Finds an Indirect Association Between Sleep & Inflammation

February 13, 2020 • By Gretchen Henkel

  • Tweet
  • Email
Print-Friendly Version / Save PDF

Tero Vesalainen / shutterstock.comIn a study in Arthritis Care & Research, researchers showed an indirect association between osteoarthritis (OA) and sleep health in older men.1 In those participants with OA, the condition is associated with poorer sleep health, as well as a 16% higher incidence of elevated C-reactive protein and 12% higher odds of having elevated interleukin 6. It may be, say two authors connected with the study, that assessing patients’ sleep patterns and sleep health would be useful adjuncts in the ongoing management of these patients.

You Might Also Like
  • Sleep Therapy May Help Ease Knee Pain
  • Poor Sleep Associated with Higher Risk of Chronic Pain
  • Poor Sleep Quality During Menopause Tied to Increased Inflammation
Explore This Issue
February 2020
Also By This Author
  • The Evolution of Glucocorticoids

Alerted to Rich Data Set

In previous research conducted at Pennsylvania State University, lead author Soomi Lee, PhD, focused on sleep health across the lifespan. She has explored the predictors of sleep health and how those differ between age groups, such as adolescents vs. middle-aged workers. Currently assistant professor in the School of Aging Studies at the University of South Florida, Tampa, Dr. Lee has been turning her focus to sleep patterns in older adults.

Dr. Lee

Dr. Lee

“Because I was interested in sleep health in older adults, I was paying attention to a news alert and found that the dataset from the NIA/NIAMS [National Institute on Aging/National Institute of Arthritis and Musculoskeletal and Skin Diseases] sponsored study, Osteoporotic Fractures in Men Study (MrOS), was publicly available,” Dr. Lee says, describing the genesis of her latest study. The National Institute on Aging, in collaboration with Sutter Health’s California Pacific Medical Center Research Institute, released the dataset in November 2017.2

That longitudinal study featured 16 years’ worth of anonymous data collected from 5,994 community-dwelling older men. The study was coordinated by investigators at six academic institutions: University of Alabama, Birmingham; University of Minnesota; University of Pittsburgh; Stanford University; Oregon Health & Science University; and University of California, San Diego. Participants were examined at baseline for fracture risk.

ad goes here:advert-2
ADVERTISEMENT
SCROLL TO CONTINUE

But the additional bonanza for investigators is the wealth of data collection. At regular intervals, MrOS researchers conducted spinal X-rays and bone density exams and collected serum samples. They also assessed other factors, such as oral health, sleep health and patterns, and markers for cardiovascular disease.

What caught Dr. Lee’s attention about the public release of the dataset is that 3,135 men in the MrOS study participated in an ancillary sleep study from 2003–2005. Participants were first screened for use of any mechanical devices during sleep, such as pressure masks for sleep apnea or oxygen therapy, and those who used such devices were excluded from the sleep study. Sleep patterns were assessed for the resulting number of participants (2,562) via self-report questionnaires, and actigraphy was used to assess periods of sleep and wakefulness. In addition, other routine measures used in the MrOS study were noted, especially urine and serum specimen collection.

Pages: 1 2 3 | Single Page

Filed Under: Conditions, Osteoarthritis, Research Reviews Tagged With: Sleep, systemic inflammationIssue: February 2020

You Might Also Like:
  • Sleep Therapy May Help Ease Knee Pain
  • Poor Sleep Associated with Higher Risk of Chronic Pain
  • Poor Sleep Quality During Menopause Tied to Increased Inflammation
  • Within Our Reach–Funded Study Finds Increased Depression Risk Among Some RA Patients

Simple Tasks

Learn more about the ACR’s public awareness campaign and how you can get involved. Help increase visibility of rheumatic diseases and decrease the number of people left untreated.

Visit the Simple Tasks site »

American College of Rheumatology

Visit the official website for the American College of Rheumatology.

Visit the ACR »

Meeting Abstracts

Browse and search abstracts from the ACR Convergence and ACR/ARP Annual Meetings going back to 2012.

Visit the Abstracts site »

The Rheumatologist newsmagazine reports on issues and trends in the management and treatment of rheumatic diseases. The Rheumatologist reaches 11,500 rheumatologists, internists, orthopedic surgeons, nurse practitioners, physician assistants, nurses, and other healthcare professionals who practice, research, or teach in the field of rheumatology.

About Us / Contact Us / Advertise / Privacy Policy / Terms of Use / Cookie Preferences

  • Connect with us:
  • Facebook
  • Twitter
  • LinkedIn
  • YouTube
  • Feed

Copyright © 2006–2023 American College of Rheumatology. All rights reserved.

ISSN 1931-3268 (print)
ISSN 1931-3209 (online)