“It is also essential to remember that both TBLC and SLB are imperfect tests and there remains a clear need for better diagnostics such as molecular classifiers that can remove the reliance on histopathological pattern. Similar to the COLDICE study, it is imperative that studies evaluating the next generation of novel diagnostics use rigorous methods to convince the skeptics and justify inclusion of these tests in future diagnostic algorithms,” the editorialists conclude.
Funding for the study was provided by University of Sydney, Hunter Medical Research Institute, Erbe Elektromedizin, Medtronic, Cook Medical, Rymed, Karl-Storz, Zeiss and Olympus.
Dr. Troy did not respond to a request for comment by press time.
- Troy LK, Grainge C, Corte TJ, et al. Diagnostic accuracy of transbronchial lung cryobiopsy for interstitial lung disease diagnosis (COLDICE): A prospective, comparative study. Lancet Respir Med. 2019 Sep 27. pii: S2213-2600(19)30342-X. [Epub ahead of print]
- Ryerson CJ, Johannson KA. Transbronchial lung cryobiopsy in ILD: The data we’ve been waiting for. Lancet Respir Med. 2019 Sep 27. pii: S2213-2600(19)30344-3. [Epub ahead of print]