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What Clinicians Should Know About Midfoot Osteoarthritis

Yvonne M. Golightly, PT, MS, PhD, Jill Halstead, BSc, MSc, PhD, MRCPod, John B. Arnold, PhD, Lara S. Chapman, MSc, BPod, Catherine J. Bowen, PhD, BPod, Marian T. Hannan, DSc, MPH, Hylton B. Menz, PhD, BPod, Kade L. Paterson, PhD, BPod, BAppSci(Hons) & Martin J. Thomas, PhD, MCSP  |  Issue: October 2025  |  October 8, 2025


Yvonne M. Golightly, PT, MS, PhD, is a professor and assistant dean for research at the University of Nebraska Medical Center College of Allied Health Professions, Omaha, Neb.

Jill Halstead, PhD, MRCPod, is a clinical lead for research, Leeds Community Healthcare NHS Trust, visiting research fellow and NIHR senior clinical research practitioner awardee at the University of Leeds, U.K.

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John B. Arnold, PhD, a senior lecturer in the Allied Health & Human Performance Unit at the University of South Australia.

Lara Chapman, is a podiatrist and NIHR doctoral fellow at Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, U.K.

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Catherine J. Bowen, PhD, BPod, is a professor of podiatry at the University of Southampton, U.K.

Marian T. Hannan, DSc, MPH, is a professor of medicine at Harvard Medical School and senior scientist at the Marcus Institute for Aging Research, Hebrew SeniorLife, Boston.

Hylton B. Menz, PhD, BPod, is a professor of podiatry at La Trobe University, Melbourne, Victoria, Australia.

Kade L. Paterson, PhD, BPod, BAppSci(Hons), is a Principal Research Fellow and a Dame Kate Campbell Fellow with the Centre for Health, Exercise and Sports Medicine in the Department of Physiotherapy at the University of Melbourne, Australia.

Martin J. Thomas, PhD, MCSP, is a senior research fellow in clinical epidemiology at Keele University and honorary specialist rheumatology and musculoskeletal physiotherapist at the Midlands Partnership University NHS Foundation Trust, U.K.

References

  1. Roddy E, Thomas MJ, Marshall M, et al. The population prevalence of symptomatic radiographic foot osteoarthritis in community-dwelling older adults: Cross-sectional findings from the clinical assessment study of the foot. Ann Rheum Dis. 2015 Jan;74(1):156–163.
  2. Thomas MJ, Peat G, Rathod T, et al. The epidemiology of symptomatic midfoot osteoarthritis in community-dwelling older adults: Cross-sectional findings from the Clinical Assessment Study of the Foot. Arthritis Res Ther. 2015 Jul 13;17(1):178.
  3. Arnold JB, Marshall M, Thomas MJ, et al. Midfoot osteoarthritis: potential phenotypes and their associations with demographic, symptomatic and clinical characteristics. Osteoarthritis Cartilage. 2019 Apr;27(4):659–666.
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  17. Menz HB, Munteanu SE, Landorf KB, et al. Radiographic classification of osteoarthritis in commonly affected joints of the foot. Osteoarthritis Cartilage. 2007 Nov;15(11):1333–1338.
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  19. Keiserman LS, Cassandra J, Amis JA. The piano key test: A clinical sign for the identification of subtle tarsometatarsal pathology. Foot Ankle Int. 2003 May;24(5):437–438.
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  21. Camerer M, Ehrenstein B, Hoffstetter P, et al. High-resolution ultrasound of the midfoot: Sonography is more sensitive than conventional radiography in detection of osteophytes and erosions in inflammatory and non-inflammatory joint disease. Clin Rheumatol. 2017 Sep;36(9):2145–2149.
  22. Lim PQX, Menz HB, Landorf KB, et al. Assessment and management of midfoot osteoarthritis by podiatrists in Australia: A cross-sectional survey of current practice. Rheumatol Int. 2025 May 12;45(6):141.
  23. Yi T, Kim JH, Oh-Park M, Hwang JH. Effect of full-length carbon fiber insoles on lower limb kinetics in patients with midfoot osteoarthritis: A pilot study. Am J Phys Med Rehabil. 2018 Mar;97(3):192–199.
  24. Rao S, Baumhauer JF, Becica L, Nawoczenski DA. Shoe inserts alter plantar loading and function in patients with midfoot arthritis. J Orthop Sports Phys Ther. 2009 Jul;39(7):522–531.
  25. Halstead J, Chapman GJ, Gray JC, et al. Foot orthoses in the treatment of symptomatic midfoot osteoarthritis using clinical and biomechanical outcomes: A randomised feasibility study. Clin Rheumatol. 2016 Apr;35(4):987–996.
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  29. Paterson KL, Harrison C, Britt H, et al. Management of foot/ankle osteoarthritis by Australian general practitioners: An analysis of national patient-encounter records. Osteoarthritis Cartilage. 2018 Jul;26(7):888–894.
  30. Drakonaki EE, Kho JSB, Sharp RJ, Ostlere SJ. Efficacy of ultrasound-guided steroid injections for pain management of midfoot joint degenerative disease. Skeletal Radiol. 2011 Aug;40(8):1001–1006.
  31. Protheroe D, Gadgil A. Guided intra-articular corticosteroid injections in the midfoot. Foot Ankle Int. 2018 Aug;39(8):1001–1004.
  32. Patel A, Rao S, Nawoczenski D, et al. Midfoot arthritis. J Am Acad Orthop Surg. 2010 Jul;18(7):417–425.
  33. Arnold JB, Halstead J, Grainger AJ, et al. Foot and leg muscle weakness in people with midfoot osteoarthritis. Arthritis Care Res (Hoboken). 2021 Jun;73(6):772–780.
  34. Peiris WL, Cicuttini FM, Hussain SM, et al. Is adiposity associated with back and lower limb pain? A systematic review. PLoS One. 2021 Sep;16(9):e0256720.

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Filed under:ConditionsGuidanceInterprofessional PerspectiveOsteoarthritis and Bone DisordersResearch Rheum Tagged with:DisparitiesExercisefootimagingmidfoot oteoarthritisNSAIDsorthoticsPainpodiatryquality of life

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