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The Rheumatologist: August 2020

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ACR Releases COVID-19 & MIS-C Clinical Guidance for Kids with Rheumatic Disease

Gretchen Henkel  |  August 12, 2020

The ACR has released clinical guidance documents for pediatric patients with rheumatic disease in the context of the COVID-19 pandemic, including one for multi-system inflammatory syndrome in children (MIS-C). Jay Mehta, MD, MS, an attending physician in the Division of Rheumatology and director of the Pediatric Rheumatology Fellowship at the Children’s Hospital of Philadelphia (CHOP),…

The Problem with Peer Review

Philip Seo, MD, MHS  |  August 12, 2020

I should have paid more attention in medical school. If I had, I might have remembered enough about basic pathophysiology to know why everyone was suddenly pulling their patients off of lisinopril. For those of you who need a quick primer: When the pressure in the renal artery drops, the kidney secretes renin. Working together,…

ACR Convergence 2020: Reimagining the ACR/ARP Annual Meeting

Ellen M. Gravallese, MD  |  August 5, 2020

Looking back on last year’s ACR/ARP annual meeting, I recall the energy and excitement of attendees as they participated in sessions covering the latest scientific concepts and new directions in our field. In 2019, we piloted a number of innovative ways to modernize and enhance future ACR meetings, with the promise of delivering a transformed…

9 Steps to Transform Your Rheumatology Practice

Erin Arnold, MD; William Arnold, MD; Gary Crump, MD; David Sikes, MD; Drew Johnson, MS, MBA; & Timothy Harrington, MD  |  August 12, 2020

The ACR position statement on access to care proposes the goal that “… all patients have timely access to expert rheuma­tology care … .”1 The reality is that new and established rheumatology patient wait times are often prolonged, causing delays in necessary diagnosis and treatment. The 2005 and 2015 ACR Workforce studies document intractable and…

COVID-19: Most Individuals with Rheumatic Disease Recover

Lara C. Pullen, PhD  |  June 19, 2020

An analysis of data from the COVID-19 Global Rheumatology Alliance registry shows that use of disease-modifying antirheumatic drugs or non-steroidal anti-inflammatory drugs did not increase the risk of hospitalization for COVID-19 patients with rheumatic disease, but steroid use did.

Rheumatology Biologic Expertise Valued for COVID-19 Treatment Decisions

Catherine Kolonko  |  May 18, 2020

At the Loma Linda University Medical Center, Calif., rheumatologists play a key consulting role for COVID-19 patients who may benefit from the use of biologic treatments…

Dr. Kawasaki

Tomisaku Kawasaki, Pediatrician Who Discovered Disease That Bears His Name, Dies at 95

Renée Bacher  |  June 18, 2020

Japanese pediatrician Tomisaku Kawasaki, MD, who identified an inflammatory syndrome that affects children, died on June 5 in Tokyo. He was 95. Tenacity & Attention to Detail Born Feb. 7, 1925, in Tokyo, Dr. Kawasaki graduated from medical school at what is now Chiba University in Chiba, Japan, in 1948 and worked as staff pediatrician…

In Memoriam … J. Timothy Harrington, MD, MACR: July 6, 1940–June 23, 2020

William Arnold, MD; Tim Bartholow, MD; Drew Johnson, MS, MBA; Joel Kremer, MD; Daniel Malone, MD; Eric D. Newman, MD; Kenneth Saag, MD; & Douglas White, MD  |  June 30, 2020

June saw the passing of a beloved colleague, mentor and friend to many in the rheumatology community when J. Timothy Harrington, MD, died of pancreatic cancer in his hometown of Madison, Wis. Dr. Harrington trained at Massachusetts General Hospital, the National Institutes of Health National Cancer Institute and UT Southwestern Medical Center, and served on…

Talk It Up! 5th Annual Rheumatic Disease Awareness Month

Ruth Jessen Hickman, MD  |  August 17, 2020

This September marks the ACR’s fifth annual Rheumatic Disease Awareness Month (RDAM), which is designed to build support and advocate for patients with rheumatic diseases. This year’s theme, “My disease may be invisible, but I’m not,” emphasizes patients’ personal experiences…

A transverse view of the ulnar groove in full elbow extension. The red arrow indicates the advancing edge of the MHTr.

Recurrent Medial Elbow Pain Following Successful Tommy John Surgery

Mark H. Greenberg, MD, RMSK, RhMSUS, A. Lee Day, MD, RMSK, James W. Fant Jr., MD, & Christopher G. Mazoue, MD  |  August 12, 2020

A 27-year-old, left-handed man was referred to our ultrasound clinic for left elbow pain. History The patient had been a pitcher on a Minor League Baseball team. Two years before, he developed sudden, severe medial elbow pain while pitching in a game. The pain was associated with some tingling down the left medial forearm. The…

The Importance of Community: Rheumatology Professionals Find Different Ways to Support Their Patients & Neighborhoods

Kimberly Retzlaff  |  July 13, 2020

Working in support of underserved communities, making and donating masks, volunteering with local rheumatic disease-focused organizations—these are just some of the ways rheumatology professionals have been giving back to their patients and communities…

Case Report: What’s Causing This Severe Case of Rhabdomyolysis?

Aditya S. Pawaskar, MBBS, MD, & Weishali V. Joshi, MD  |  August 12, 2020

Rhabdomyolysis is a clinical syndrome characterized by muscle tissue necrosis and release of intramuscular components into the circulation. Typical manifestations include muscle pain and myoglobinuria, causing dark urine. Serum creatinine kinase (CK) enzyme levels are usually markedly elevated. Severity can range from muscle enzyme elevation in the serum of an otherwise asymptomatic patient to extremely…

Case Report: Diagnosing a Lupus-Flare Mimic

Nobuya Abe, MD, Yuichiro Fujieda, MD, PhD, & Tatsuya Atsumi, MD, PhD  |  August 12, 2020

The diagnosis of rheumatic diseases requires the exclusion of other systemic disorders. Infection, hematologic conditions, malignancies and some drugs may all lead to syndromes that closely mimic rheumatic diseases, which may lead to diagnostic delays. Idiopathic multicentric Castleman disease (iMCD) is a heterogeneous group of lympho­proliferative diseases (LPDs) characterized by systemic inflammatory manifestations.1,2 As with…

Figure 1A–C: Arrows denote hemophagocytic histiocytes.

Case Report: Too Many Activated Immune Cells in a 9-Month-Old Boy

Jeffrey Lo, MD  |  August 12, 2020

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease of immune dysregulation characterized by unchecked inflammatory responses leading to end-organ dysfunction. Primary HLH results from inherited mutations that impair the capacity for immune regulation; secondary HLH arises from the inappropriate response to an immune stimulus, such as infection, malignancy or autoimmunity. What is less well known is…

How to Create a Safe Practice & Prep for a COVID-19 Resurgence

Steven M. Harris, Esq.  |  August 12, 2020

For many months, the healthcare world has been significantly affected by the swift and per­vasive effects of SARS-CoV-2, which causes COVID-19. The virus has severely affected the delivery of patient care by all providers, including those in hospitals and emergency care settings, who grappled with the response to massive influxes of COVID-19 patients, and those…

Rheum After 5: Dr. Eric Matteson Writes Rheumatic Disease History

Carol Patton  |  August 12, 2020

Over the past 20 years, Eric L. Matteson, MD, MPH, emeritus chair, Division of Rheumatology, and emeritus professor of medicine at the Mayo Clinic College of Medicine and Science, Rochester, Minn., as well as a past president of the Rheumatology Research Foundation, has authored or co-authored six books about the history of rheumatic disease and…

Interleukin 17 Inhibitors Promising in Ankylosing Spondylitis Patients

Michele B. Kaufman, PharmD, BCGP  |  July 10, 2020

In patients with active ankylosing spondylitis, IL-17 inhibitors have produced favorable responses, according to recent research…

Apremilast Promising for Plaque Psoriasis

Michele B. Kaufman, PharmD, BCGP  |  July 6, 2020

Apremilast has been shown to improve the signs and symptoms of mild to moderate plaque psoriasis in adults, according to new research…

ABX464 in Phase 2a Trials for RA

Michele B. Kaufman, PharmD, BCGP  |  June 29, 2020

Research is examining the safety and tolerability of two different doses of ABX464 in patients with moderate to severe active RA…

Biologic Treatment Recommendations for Rheumatic Disease Patients Who Contract COVID-19

Thomas R. Collins  |  July 7, 2020

COVID-19 Global Alliance registry and other data on rheumatic disease patients with COVID-19 were presented…

A Primer on the Management of Scleroderma Emergencies

Jason Liebowitz, MD, FACR  |  July 14, 2020

Patient with autoimmune disease may experience medical emergencies. Here is an overview of recognition and management of three emergent situations for patients with scleroderma: critical digital ischemia, scleroderma renal crisis and intestinal pseudo-obstruction…

Malignant Complications: Screening for Cancer in Rheumatic Diseases

Jason Liebowitz, MD, FACR  |  July 13, 2020

Cancer and autoimmunity have a complex relationship. In a presentation, Ami Shah, MD, MHS, discussed how to use autoantibodies as tools for cancer risk stratification, how to approach cancer screening in individuals with new-onset disease and more…

Bone Density Concerns: Guidance on Tackling Fracture Risk in CKD

Thomas R. Collins  |  July 7, 2020

Suggestions on how to assess risk and manage bone issues in chronic kidney disease patients are offered…

EULAR & ACR COVID-19 Recommendations: How to Manage Patients During the COVID-19 Pandemic

Thomas R. Collins  |  June 23, 2020

ACR & EULAR recommendations for the treatment of patients with rheumatic illness during the COVID-19 pandemic are explored…

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