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You are here: Home / Search for "fracture"

Search results for: fracture

Vitamin D, Calcium Supplements May Not Lower Fracture Risk

January 1, 2018 • By Lisa Rapaport

(Reuters Health)—Older adults who take vitamin D and calcium are no less likely to break their hips or other bones than peers who don’t use these supplements, a research review suggests. Researchers examined data from 33 previous trials with a total of more than 51,000 people aged 50 or older who were living in the… [Read More]

Filed Under: Conditions Tagged With: bone mineral density (BMD), calcium, Fractures, hip fracture, Osteoporosis, osteoporosis treatments, Vitamin D

Rheumatology Drug Updates: Hip Fracture Rates After Bisphosphonate Drug Holidays, Plus More on Golimumab, Ustekinumab

December 19, 2017 • By Michele B. Kaufman, PharmD, BCGP

Bisphosphonate Drug Holidays Drug holidays are common for patients on bisphosphonate therapy. Often, these breaks in treatment are related to known U.S. Food and Drug Administration (FDA) warnings and drug class adverse effects. Currently, data on fracture risk related to drug holidays are limited. In recent research highlighted at the 2017 ACR/ARHP Annual Meeting ,… [Read More]

Filed Under: DMARDs & Immunosuppressives, Drug Updates, Spondyloarthritis Tagged With: Ankylosing Spondylitis, Approval, Bisphosphonate, bone loss, drug therapy, FDA, Fractures, Golimumab, hip, Osteoporosis, osteoporosis treatments, outcome, patient care, plaque psoriasis, Research, rheumatology, risk, Safety, ustekinumab, warning

Vitamin D-Metabolite Ratio Predicts Fracture Risk Better than 25(OH)D

December 14, 2017 • By Anne Harding

NEW YORK (Reuters Health)—Vitamin D-metabolite ratio (VMR) may be a better marker of bone health than 25(OH)D (25-hydroxyvitamin D), a new study suggests. “The parameter that’s currently used to assess vitamin D status, 25(OH)D, is a flawed measure because it doesn’t consistently associate with important bone outcomes like hip fractures,” Dr. Charles Ginsberg of Veterans… [Read More]

Filed Under: Conditions, Drug Updates Tagged With: 25(OH)D (25-hydroxyvitamin D), bone health marker, fracture risk, Fractures, vitamin D-metabolite ratio

Bisphosphonate Drug Holiday & Hip Fracture Risk

November 21, 2017 • By Michele B. Kaufman, PharmD, BCGP

New research found women on bisphosphonate therapy who take a drug holiday experience a higher rate of hip fracture…... [Read More]

Filed Under: Drug Updates Tagged With: Bisphosphonate, bisphosphonates, drug holiday, Fractures, hip, hip fracture, hip fracture risk, Osteoporosis, osteoporosis treatments

Bisphosphonates May Limit Fracture Risk in Users of Oral Glucocorticoids

November 8, 2017 • By Reuters Staff

NEW YORK (Reuters Health)—Early oral bisphosphonate use is associated with a lower risk of fractures among oral-glucocorticoid users, researchers from Canada report. Bisphosphonates are commonly used for glucocorticoid-induced osteoporosis, but their efficacy has been established only in primary osteoporosis, where the mechanism of action of bone loss differs from that seen with glucocorticoid use. Dr…. [Read More]

Filed Under: Conditions, Drug Updates Tagged With: Bisphosphonate, Canada report, early oral bisphosphonate use, fracture risk, Fractures, Glucocorticoid-Induced Osteoporosis, oral-glucocorticoid users, Osteoporosis

Sequential Therapy May Reduce Hip Fracture Risk; Plus New Biosimilar Available in Canada

September 27, 2017 • By Michele B. Kaufman, PharmD, BCGP

Patients who receive abaloparatide and switch to alendronate have a statistically significant reduction in fracture risk through 3.5 years, according to a new study…... [Read More]

Filed Under: Biologics & Biosimilars, Drug Updates Tagged With: abaloparatide, alendronate, Biologics & Biosimilars, etanercept, etanercept-szzs, Fractures, hip, hip fracture, hip fracture risk

Undetected Fractures Linked to Back Pain in Older Men

September 22, 2017 • By Shereen Lehman

(Reuters Health)—About three in five older men with tiny spinal fractures related to osteoporosis reported new or worsening back pain in a new study. Only about one-quarter of new vertebral fractures are diagnosed by a doctor, the study team writes in their September 7 online report in Journal of Bone and Mineral Research, though the… [Read More]

Filed Under: Conditions Tagged With: Back pain, Fractures, older men, Osteoporosis, undetected fractures, vertebral fracture

Alendronate Decreases Hip Fracture Risk in Older Patients Using Oral Prednisolone

August 21, 2017 • By Lara C. Pullen, PhD

New research found that older patients on prednisolone who are also treated with alendronate experience a significantly lower risk of hip fracture. Alendronate use was also associated with a lower risk of death…... [Read More]

Filed Under: Conditions Tagged With: alendronate, elderly, Fractures, hip fracture, hip fracture risk, prednisolone

A New Approach to Fracture Prevention

December 14, 2016 • By Susan Bernstein

Glucocorticoids are widely prescribed by rheumatologists, and the effects of daily and cumulative doses of these drugs on bone mineral density (BMD) are important elements of a draft clinical guideline document presented on Nov. 13 at the 2016 ACR/ARHP Annual Meeting in Washington, D.C. Leaders of the ACR guideline project discussed their recommendations at the… [Read More]

Filed Under: Guidelines, Meeting Reports, Professional Topics Tagged With: 2016 ACR/ARHP Annual Meeting, draft clinical guideline, fracture risk factors, Fractures, Glucocorticoid-Induced Osteoporosis, Glucocorticoid-Induced Osteoporosis Prevention and Treatment: An Updated ACR Clinical Guideline, Glucocorticoids, Osteoporosis

Denosumab Linked to Rebound-Associated Fractures in Nine Patients

October 21, 2016 • By Reuters Staff

NEW YORK (Reuters Health)—Patients can develop rebound-associated vertebral fractures after stopping denosumab, a new report of nine cases shows. All of the patients were considered to be at low risk of fracture, and the fractures occurred within nine to 16 months of their last injection, Dr. Olivier Lamy and colleagues from Lausanne University Hospital in Switzerland… [Read More]

Filed Under: Conditions, Professional Topics Tagged With: bone mineral density (BMD), bone turnover rebound (BTR), denosumab, Fractures, Osteoporosis, osteoporosis treatments, vertebral fracture

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