Rheumatic diseases, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and vasculitis, can affect the body in many ways, but perhaps the most serious is the increased risk of heart disease for many patients. As the risk of atherosclerosis in autoimmune disease patients gains increased attention, rheumatologists and cardiologists are collaborating more often to…
Search results for: joint pain
Exercise Guidelines for Fibromyalgia Patients
Fibromyalgia syndrome (FMS) is a condition characterized by widespread pain, abnormal pain processing, sleep disturbance and fatigue. It is commonly associated with psychological distress and co-morbid conditions. Impaired cognition is common in individuals with FMS, and is often referred to as fibrofog.1 According to the U.S. Centers for Disease Control and Prevention, the prevalence of…
Auto-Injectable Methotrexate: New Treatment Option for RA
Methotrexate has long been a cornerstone of therapy in rheumatoid arthritis. Two new, injectable methotrexate products may help some RA patients for whom oral methotrexate is not as effective or causes adverse effects. Rasuvo and Otrexup are prefilled, auto-injection devices that allow patients to give themselves subcutaneous injections of methotrexate without having to use a…
Phase 3 Trials: Secukinumab for Psoriatic Arthritis & DA-DKP for OA
In a global Phase 3 trial, subcutaneous secukinumab proved safe and effective in patients with psoriatic arthritis. Also, a version of aspartyl-alanyl diketopiperazine, a biologic for knee OA, has entered Phase 3 trials…
Case Report: Interstitial Lung Disease with Positive ANCA Test
“Worst of all is the pain in my calves,” she said. “It feels like burning deep inside.” So began my first encounter with a 69-year-old woman who was referred to rheumatology clinic for evaluation of two months of constitutional symptoms and a positive ANCA test, which had been ordered by her primary care doctor. Her…
Weight-Bearing Exercise Eases Knee Osteoarthritis, Temporarily
(Reuters Health)—A program of weight-bearing exercise reduces pain and improves joint function, at least for two to six months, for people with osteoarthritis, according to a review of previous trials. “We had a systematic review for Cochrane from 2008 and 2009, but there were much less articles,” said Dr. Martin Van der Esch, who coauthored…
Rituximab for RA Is Safe Long Term, Plus Oxycodone Update
Rituximab was evaluated and found safe as a long-term RA therapy. Also, FDA Advisory Committees voted on oxycodone therapies at a joint meeting.
Smartphone Apps Make Virtual House Calls
Telemedicine apps used on mobile devices may help rheumatologists connect with select patients, increasing practice efficiency and patient access to treatment…
Subcutaneous Golimumab in Active Non-Radiographic Axial Spondyloarthritis
Patients with non-radiographic axSpA experience reduced mobility and quality of life. In this study, researchers investigated the effect of treatment for nr-axSpA every four weeks with SQ golimumab (GLM). Seventy-one percent of patients in the GLM group achieved ASAS 20 response at Week 16, compared with 40.0% in the control group…
Depression & Anxiety Linked to Poor Rheumatoid Arthritis Outcomes
NEW YORK (Reuters Health)—Rheumatoid arthritis patients with depression and anxiety symptoms may have worse outcomes and poorer response to prednisolone, a secondary analysis of the CARDERA trial has found. “The strength of association between depression/anxiety and disease activity outcomes and treatment response warrants routine screening,” the study’s lead author Faith Matcham at King’s College London…
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