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Search results for: FLARE

Does Switching from IV to Subcutaneous Tocilizumab Affect RA Disease Flare?

Michele B. Kaufman, PharmD, BCGP  |  December 9, 2021

Researcher identified multiple factors for flare, including non-use of methotrexate, in patients with rheumatoid arthritis who had switched from intravenous (IV) tocilizumab to subcutaneous tocilizumab.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2021ACR Convergence 2021 – RAIV tocilizumabRA flaressubcutaneous tocilizumabtocilizumab

Patients with Rheumatic Disease May Experience Flares after SARS-CoV-2 Vaccination

Linda Carroll  |  July 12, 2021

(Reuters Health)—Among a group of New York patients with rheumatic diseases who received a SARS-CoV-2 vaccine, nearly one in six experienced disease flares after getting their shots, a new study finds.1 A survey of more than 1,100 patients who had received at least one vaccine dose revealed that 14.9% experienced flares. Among the 654 who…

Filed under:Conditions Tagged with:COVID-19FlaresSARS-CoV-2Systemic Rheumatic Diseasesvaccinationvaccine

COVID-19 Puts Latino Patients with Rheumatic Disease at Risk of a Disease Flare

Arthritis & Rheumatology  |  June 28, 2021

In their new study, Fike et al. found Latino patients with rheumatic diseases have a higher rate of COVID-19 than the general Latino population. Obesity is a risk factor for COVID-19, and COVID-19 is a risk factor for rheumatic disease flare.

Filed under:ConditionsResearch Rheum Tagged with:Arthritis & RheumatologyCOVID-19FlaresLatinosObesityResearchRheumatic Disease

Alpha Tauri 3D Graphics / shutterstock.com

RA Flare Pathway

Staff  |  March 2, 2021

Alpha Tauri 3D Graphics / shutterstock.com

Study Elucidates Potential Flare Pathways in Rheumatoid Arthritis

Ruth Jessen Hickman, MD  |  December 14, 2020

Research in The New England Journal of Medicine has opened new avenues for exploring the pathophysiology of disease flares in rheumatoid arthritis.1 Through longitudinal genomic analysis, researchers have identified a naive B cell signature prior to rheumatoid arthritis flares, as well as a type of mesenchymal cell, that may play an important role in flare…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Flaresgenetics

Case Report: Diagnosing a Lupus-Flare Mimic

Nobuya Abe, MD, Yuichiro Fujieda, MD, PhD, & Tatsuya Atsumi, MD, PhD  |  August 12, 2020

The diagnosis of rheumatic diseases requires the exclusion of other systemic disorders. Infection, hematologic conditions, malignancies and some drugs may all lead to syndromes that closely mimic rheumatic diseases, which may lead to diagnostic delays. Idiopathic multicentric Castleman disease (iMCD) is a heterogeneous group of lympho­proliferative diseases (LPDs) characterized by systemic inflammatory manifestations.1,2 As with…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:Castleman's diseaseRaynaud’s phenomenon

Local Depletion of Resident Memory T Cells May Reduce Site-Specific Joint Flares

Carina Stanton  |  April 21, 2020

A study found resident memory T cells may mediate inflammatory arthritis and trigger flares in specific joints, suggesting local depletion of these cells could be a therapeutic strategy…

Filed under:ConditionsRheumatoid Arthritis Tagged with:2019 ACR/ARP Annual MeetingFlaresjointjuvenile idiopathic arthritis (JIA)Rheumatoid Arthritis (RA)

Atmospheric & Environmental Changes Tied to Organ-Specific Lupus Flares

Megan Brooks  |  November 19, 2019

NEW YORK (Reuters Health)—Changes in atmospheric and environmental factors may contribute to organ-specific disease exacerbation in patients with systemic lupus erythematosus (SLE), according to a new study. The study found “strong associations between atmospheric variables and fine particulate matter concentration over the 10 days prior to a patient visit and organ-specific lupus flares at the…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:2019 ACR/ARP Annual Meetingenvironmental factorFlaresLupussystemic lupus erythematosus (SLE)

Lupus Flares Pose Greatest Risk for Adverse Pregnancy Outcomes in Women with SLE

Lara C. Pullen, PhD  |  October 7, 2019

According to new research, women with SLE are at the highest risk for adverse pregnancy outcomes during a lupus flare. The data may enable clinicians to use risk stratification and tailored monitoring to counsel SLE patients who are pregnant or considering pregnancy. Researchers also found that maternal age, lupus nephritis and antiphospholipid antibodies may affect pregnancy outcomes…

Filed under:ConditionsSystemic Lupus Erythematosus Tagged with:flareFlaresLupusOutcomespregnancypregnancy complicationspregnant womenWomen

Shingles Vaccine Not the Only Immunization Linked with Gout Flare

Marilynn Larkin  |  August 21, 2019

NEW YORK (Reuters Health)—The recombinant shingles vaccine (RZV) is associated with an increased risk of gout flare, and a new study suggests other vaccines may trigger flares as well, researchers say. “Our findings are novel because for the first time, we have identified a trigger for gout flares that presumably acts through [an inflammatory] pathway,…

Filed under:ConditionsGout and Crystalline Arthritis

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