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Search results for: Tofacitinib

Cancer Risk for Patients with Juvenile Idiopathic Arthritis Taking TNF Inhibitors

Thomas R. Collins  |  March 20, 2017

WASHINGTON, D.C.—Juvenile idiopathic arthritis (JIA) patients taking TNF inhibitors don’t develop new cancers at a higher rate than JIA patients who don’t take TNF inhibitors, according to the largest study so far conducted to study the possible link. The findings were reported at the 2016 ACR/ARHP Annual Meeting in an abstract session that also included…

Filed under:ConditionsMeeting ReportsResearch Rheum Tagged with:2016 ACR/ARHP Annual MeetingAmerican College of Rheumatology (ACR)CancerinhibitorJuvenile idiopathic arthritisPediatricsrateResearchrheumatologyriskTNFTreatment

Baricitinib Effective for Treating Refractory Rheumatoid Arthritis

Mary Beth Nierengarten  |  February 15, 2017

Soon, rheumatologists may have another drug to offer their patients with refractory rheumatoid arthritis (RRA) for whom effective and safe treatment remains challenging. A study published in the New England Journal of Medicine shows that patients with RRA treated with once-daily baricitinib in a 4 mg dose had a significant clinical improvement in symptoms of…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:adverse eventsbaricitinibClinicaldrugoutcomepatient carerefractory rheumatoid arthritisResearchrheumatologystudyTreatmenttrial

Baricitinib Is Effective in Patients Treated with DMARDs & Methotrexate

Lara C. Pullen, PhD  |  January 30, 2017

A recent analysis has examined the effectiveness of baricitinib in treating RA patients who suffer from comorbidities and the effect of concomitant use of steroids. Baricitinib proved effective, particularly in patients who had exposure to cDMARDs and corticosteroids…

Filed under:Drug Updates Tagged with:baricitinibDisease-modifying antirheumatic drugs (DMARDs)Janus Kinase InhibitorsMethotrexate

Rheumatology Awards, Appointments and Announcements for January 2017

Ann-Marie Lindstrom  |  January 19, 2017

New Rheumatologist at Minnesota Clinic Meghan Scheibe, MD, is pleased with her new position at CentraCare Clinic Rheumatology and Infusion Services, a hospital-based practice in St. Cloud, Minn. “It’s a great practice,” says Dr. Scheibe. “Young, energetic partners and wonderful support staff. I’m seeing four to six new patients a day.” These are patients who had…

Filed under:Career DevelopmentProfiles Tagged with:appointmentsAwardsCareerProfilespromotionrheumatologistrheumatology

Infection Greater Worry Than Flare: Collaborative Guideline Offers Guidance to Prevent Joint Replacement Complications & Failure

Susan Bernstein  |  December 14, 2016

WASHINGTON, D.C.—Total joint arthroplasty is one of the most common surgical procedures performed on adults with end-stage arthritis. One recent estimate showed that 2.5 million individuals in the U.S. are living with a total hip replacement and 4.7 million are living with knee replacements. For their patients with inflammatory arthritis, rheumatologists and orthopedic surgeons must…

Filed under:Clinical Criteria/GuidelinesMeeting ReportsProfessional Topics Tagged with:2016 ACR/ARHP Annual Meetingdraft guidelineguideline projectjoint implant failurePerioperative Management of Anti-Rheumatic Medications in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplastyperioperative periodpostoperative infection

As Role of Kinase Inhibitors in Rheumatic Disease Treatment Expands, Experts Review Therapy’s Failures, Successes

Thomas R. Collins  |  October 10, 2016

LONDON—Kinase inhibitors’ profile in the world of rheumatic disease therapy is growing, and they are probably going to play an even larger and more central role as time goes on, experts said at the Annual Congress of the European League Against Rheumatism (EULAR) 2016. But Gary S. Firestein, MD, director of the Clinical and Translational…

Filed under:ConditionsMeeting ReportsResearch Rheum Tagged with:EULARfailurejanus kinase inhibitorkinase inhibitorResearchRheumatic DiseasesuccesstargettherapyTNF inhibitorTreatment

New Research into Rheumatoid Arthritis, Gout Includes Updates on Methotrexate, Biologics, Ultrasound

Thomas R. Collins  |  September 8, 2016

LONDON—From optimizing responses to methotrexate, to the efficacy of biologics, to the need for imaging in assessing remission, the literature, as ever, has been lively with explorations of pressing topics in the treatment and management of rheumatoid arthritis. Josef Smolen, MD, chair of rheumatology at the Medical University of Vienna, reviewed many of the highlights…

Filed under:ConditionsDrug UpdatesGout and Crystalline ArthritisResearch RheumRheumatoid Arthritis Tagged with:Biologicsdrug updateEULAREuropean League Against RheumatismGoutMethotrexatepatient careResearchRheumatoid arthritisrheumatologistTreatmentUltrasound

New Developments in Rheumatoid Arthritis Treatment; Personalized Therapy for Patients Ultimate Goal

Larry Beresford  |  August 11, 2016

SAN FRANCISCO—Considerable progress has been made in the treatment and management of rheumatoid arthritis (RA) in the past two decades, with rheumatologists now able to manage the effects of this chronic, debilitating condition for most of their patients, according to Ronald van Vollenhoven, MD, director of the Amsterdam Rheumatology and Immunology Center (ARC) in the…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:California Rheumatology Alliance 2016ResearchRheumatoid arthritisrheumatologistTreatment

Tips on Vaccinating Patients with Rheumatic Diseases

Thomas R. Collins  |  June 13, 2016

CHICAGO—In October of last year, a 52-year-old woman came to see Kevin Winthrop, MD, MPH, associate professor in infectious diseases, public health and preventive medicine at the Oregon Health & Sciences University. She had rheumatoid arthritis and was taking methotrexate and prednisone. She had had little change in her RA disease severity and was considering…

Filed under:ConditionsPractice Support Tagged with:2016 State-of-the-Art Clinical SymposiumFluherpes zosterpatient carepneumoniaRheumatic Diseaserheumatology

Rheumatology Drug Updates: Biosimilars Receive Positive News & More

Michele B. Kaufman, PharmD, BCGP  |  April 13, 2016

On Nov. 19, 2015, the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended granting marketing authorization for SB4, an etanercept biosimilar product that will be called Benepali.1 On Jan. 16, 2016, EMA granted marketing authorization in the European Union for Benepali to be used to treat rheumatoid arthritis (RA), psoriatic…

Filed under:Biologics/DMARDsDrug UpdatesResearch Rheum Tagged with:adalimumabApprovalsapremilastBiologicsBiosimilarsdrugEnbreletanerceptFDAHumiraResearchrheumatologySafety

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