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Search results for: allopurinol

A History of the Science, Treatment of Rheumatologic Illnesses from Gold to Gene Therapy

Simon M. Helfgott, MD  |  December 17, 2017

Mysterious Ways The juxtaposition of the old and the new was readily evident that busy Wednesday morning. My first patient, a 94-year-old gentleman, Hal, arrived with a precise request. His rheumatologist for the past 40 years had just retired, and he was searching for a doctor with expertise in the use of gold sodium aurothioglucose,…

Filed under:ConditionsOpinionResearch RheumRheuminationsSpeak Out Rheum Tagged with:American College of Rheumatology (ACR)American Rheumatism AssociationArthritisautoimmune mediated diseasebioinformaticsC-reactive proteinClinicalcorticosteroid drugsDiagnosisgenomicsHistoryimmune-suppressive therapiesinflammationknowledgemedicalpatient careResearchRheumatic Diseaserheumatologysciencetranslational researchTreatment

European Commission Approves Subcutaneous Belimumab for SLE; FDA Safety Alert for Febuxostat

Michele B. Kaufman, PharmD, BCGP  |  November 29, 2017

Subcutaneous belimumab has been approved in the EU to help treat patients with active autoantibody-positive SLE…

Filed under:ConditionsDrug UpdatesGout and Crystalline Arthritis Tagged with:belimumabcardiovascularEuropean UnionFebuxostatGoutInternationalsystemic lupus erythematosus (SLE)

How to Manage Pain & Treatment in Elderly Patients

Richard Quinn  |  August 25, 2017

Elderly patients have unique requirements with regard to treatment for pain, rheumatic disease and other ailments. Collaboration between rheumatologists, geriatricians and primary care physicians is essential to avoid unnecessary interventions and improve care for this patient population…

Filed under:Practice Support Tagged with:elderlygeriatricgeriatricspatient careTreatment

FDA Approves Duzallo for Hyperuricemia in Patients with Uncontrolled Gout

Reuters Staff  |  August 21, 2017

(Reuters)—Ironwood Pharmaceuticals Inc. said on Monday the U.S. Food and Drug Administration (FDA) approved its oral drug to treat a condition associated with gout. The company’s once-daily drug, Duzallo (lesinurad and allopurinol), was approved to treat hyperuricemia in patients with gout, Ironwood said. Duzallo combines the standard-of-care treatment, allopurinol, with Ironwood’s lesinurad to treat inefficient…

Filed under:ConditionsDrug UpdatesGout and Crystalline Arthritis Tagged with:AllopurinolFDAFood and Drug AdministrationGoutIronwood Pharmaceuticals Inc.lesinurad

How Gout Patients Can Stay on Target with the Go for Six Campaign

Karen Appold  |  May 12, 2017

Gout patients need to lower their uric acid levels to 6.0 mg/dL or below and maintain that level. According to N. Lawrence Edwards, MD, MACP, MACR, an education campaign has been raising awareness of this fact and helping gout patients…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:Go for Six campaignGoutGout & Uric Acid Education Society (GUAES)guidelinepatient education

Diagnosis of Acute Gouty Arthritis Obscured by Anchoring Bias

Diagnosis of Acute Gouty Arthritis Obscured by Anchoring Bias

Sneha Patel, MD, Monica Mohile, MD, & Arundathi Jayatilleke, MD  |  April 19, 2017

A 56-year-old African American man presents to the emergency department with polyarthralgias and a fever of 103ºF. One month prior to admission, he presented with right knee pain and swelling. Blood cultures grew S. epidermidis. He was treated for presumed septic arthritis complicated by MSSE bacteremia. He was treated with meropenem and a prolonged course…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:anchoring biasArthritiscase reportClinicalDiagnosisdiagnostic testingGoutinflammationjointoutcomepatient carepolyarthralgiaRArheumatologistrheumatologyseropositive rheumatoid arthritisTreatment

New Findings on Rheumatic Drug Therapies among Patients with Ankylosing Spondylitis, Gout, SLE

Thomas R. Collins  |  March 20, 2017

WASHINGTON, D.C.—Taking high-dose non-steroidal anti-inflammatory drugs (NSAIDs) with a TNF inhibitor as an ankylosing spondylitis (AS) patient is linked with a 61% decrease in the chances your disease will progress, suggesting there may be a synergy when the drugs are used together, according to a longitudinal observational study from researchers at the University of California,…

Filed under:Axial SpondyloarthritisConditionsGout and Crystalline ArthritisMeeting Reports Tagged with:2016 ACR/ARHP Annual MeetingAllopurinolAmerican College of Rheumatology (ACR)Ankylosing SpondylitisGoutnonsteroidal anti-inflammatory drugsNSAIDoutcomepatient careRheumatic DiseaserheumatologistrheumatologySLESystemic lupus erythematosus

Can Genetic Information Change the Clinical Care of Rheumatology Patients?

Mary Beth Nierengarten  |  February 15, 2017

WASHINGTON, D.C.—Calling it an extremely challenging topic, Peter K. Gregersen, MD, professor and head, Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute, Manhasset, N.Y., said the current role of genetics in clinical practice is less about how to use genetic information to care for patients and more about how providers and patients…

Filed under:Meeting ReportsPractice SupportResearch Rheum Tagged with:2016 ACR/ARHP Annual Meetingclinical careDiagnosisgeneticsoutcomepatient careResearchRheumatic Diseaserheumatologistrheumatology

The ACR’s Gout Guideline Co-Author Shares Insight on Treating Pain, Ongoing Patient Care

Thomas R. Collins  |  February 15, 2017

WASHINGTON, D.C.—Despite the value of guidelines, they often “are not read,” said N. Lawrence Edwards, MD, professor of medicine specializing in rheumatology at the University of Florida, at the 2016 ACR/ARHP Annual Meeting talk titled, New & Emerging Therapies for Gout, as part of the ACR Review Course. Or if they are read, they aren’t…

Filed under:ConditionsGout and Crystalline ArthritisMeeting Reports Tagged with:2016 ACR/ARHP Annual MeetingAmerican College of Rheumatology (ACR)ClinicalDr. N. Lawrence EdwardsGoutguidelineManagementPainrecommendationRheumatic DiseaserheumatologistrheumatologyTreatment

Gout Treatments Effective If Patients Maintain Lifelong Adherence to Therapies

Karen Appold  |  January 19, 2017

Although gout is one of the most effectively treated of all rheumatic diseases, it is among the worst-managed diseases long term, as shown by many studies. “Treatments are excellent, yet are dramatically under-utilized,” says Theodore Fields, MD, FACP, rheumatologist, Hospital for Special Surgery (HSS), New York. “This is because some gout patients feel better between…

Filed under:ConditionsGout and Crystalline ArthritisResearch Rheum Tagged with:ArthritisAssociation of Rheumatology Professionals (ARP)ClinicalGoutmaintenanceoutcomepatient careResearchtherapyTreatment

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