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Search results for: anifrolumab

Representation of the molecular structure of interferon a.

Interferons in Systemic Lupus Erythematosus

Katie Robinson  |  March 21, 2024

Current knowledge of receptor-ligand interactions, cell signaling, and transcriptional regulation derive from studies of type I interferon. The design of novel therapeutics is informed by the advances in investigation of type I interferon, with the potential for important impacts on patient management.

Filed under:American College of RheumatologyConditionsResearch RheumSystemic Lupus Erythematosus Tagged with:Arthritis & RheumatologyImmunologyinterferon

The Complexity of SLE Drug Research

Ruth Jessen Hickman, MD  |  December 6, 2022

PHILADELPHIA—On Saturday, Nov. 12, at ACR Convergence 2022, Joan T. Merrill, MD, director of clinical projects in the Arthritis & Clinical Immunology Program at the Oklahoma Medical Research Foundation in Oklahoma City, gave a presentation on the future of drug development and treatments for systemic lupus erythematosus (SLE). She described how an in-depth understanding of…

Filed under:ACR ConvergenceConditionsDrug UpdatesMeeting ReportsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2022LupusSLETreatment

Updated Perioperative Guideline Released: Recommendations Balance Risks of Infection & Disease Flare

Ruth Jessen Hickman, MD  |  September 13, 2022

The 2017 recommendations are updated to reflect changes in medical literature, as well as to include newly approved drugs.

Filed under:Clinical Criteria/GuidelinesConditions Tagged with:guidelinePerioperative Management of Anti-Rheumatic Medications in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplastytotal hip arthroplastytotal knee arthroplasty

What’s New in SLE: Pathogenesis & Novel Therapies

Samantha C. Shapiro, MD  |  September 8, 2022

Thomas Dörner, MD, reviewed the current state of systemic lupus erythematosus (SLE) management, providing updates on novel therapies and insights into the pathogenesis of SLE.

Filed under:ConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:anifrolumabbelimumabEULARPathogenesisSLEsystemic lupus erythematosus (SLE)voclosporin

Dermatologist, Rheumatologist Discuss Refractory Cutaneous Lupus Case

Richard D. Sontheimer, MD, & Samantha C. Shapiro, MD  |  September 5, 2022

As a dermatologist/internist with a career-long subspecialty interest in the cutaneous manifestations of the rheumatic diseases, I found the case of refractory acute cutaneous lupus by Samantha C. Shapiro, MD, in the June 2022 issue of The Rheumatologist intriguing in several ways, and I felt my perspectives on this case might provide additional educational value…

Filed under:ConditionsOpinionSpeak Out RheumSystemic Lupus Erythematosus Tagged with:case reportcutaneous lupus erythematosus (CLE)Dermatologydiagnostic imagingimage caseimage case reportletter to the editor

An Evidence-Based Drug Update & Guidance for Rheumatologists

Samantha C. Shapiro, MD  |  August 14, 2022

ORLANDO—Despite the COVID-19 pandemic, the past two years have been exciting for rheumatology providers and patients. We’ve seen the U.S. Food & Drug Administration (FDA) approve new therapies and expand indications for established drugs. At the 2022 ACR Education Exchange, Jeffrey Curtis, MD, MS, MPH, Marguerite Jones Harbert-Gene Ball Endowed professor of medicine, Division of…

Filed under:Drug UpdatesEducation & TrainingMeeting ReportsOther ACR meetings Tagged with:AAV FocusRheumACR Education ExchangeU.S. Food and Drug Administration (FDA)

Difficult-to-Treat Lupus: When & How to Use New Therapies

Samantha C. Shapiro, MD  |  July 21, 2022

Clinicians have numerous treatment options for SLE; in a EULAR 2022 session, some of the newer therapies were reviewed.

Filed under:ConditionsEULAR/OtherMeeting ReportsSystemic Lupus Erythematosus Tagged with:belimumabEULARHCQHydroxychloroquine (HCQ)rituximabSLEsystemic lupus erythematosus (SLE)

Lupus Update 2021: Classification Criteria, Disease Activity Measures & More

Jason Liebowitz, MD, FACR  |  December 2, 2021

An SLE expert discusses the latest SLE stats, classification criteria, disease activity tracking, drugs & more.

Filed under:ACR ConvergenceConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:ACR Convergence 2021ACR Convergence 2021 – SLE

Highlights, Pearls & News from ACR Convergence 2020

Vanessa Caceres  |  March 15, 2021

ACR CONVERGENCE 2020—In a year like no other, the 2020 virtual ACR Convergence was a meeting like no other. Nonetheless, the meeting introduced a healthy mix of clinical insights and take-home pearls, according to panelists in the meeting’s closing session, Bright Future: Discovery & Growth.  In this session, panelists discussed some of the biggest news…

Filed under:ConditionsRheumatoid ArthritisSystemic Lupus Erythematosus Tagged with:ACR Convergence 2020COVID-19Diet

A Year to Remember: Dr. Jinoos Yazdany Presents the 2020 Clinical Research Review

Jason Liebowitz, MD, FACR  |  December 7, 2020

During ACR Convergence 2020, Jinoos Yazdany, MD, MPH, discussed innovative research into a potential treatment for lupus, medication tapering & more. These findings may influence the treatment of rheumatic disease in the future.

Filed under:ACR ConvergenceConditionsMeeting ReportsResearch Rheum Tagged with:ACR Convergence 2020anifrolumabaxial spondyloarthritis (SpA)Clinical researchCOVID-19GlucocorticoidsLupusrituximabVasculitis

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