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Study Elucidates Potential Flare Pathways in Rheumatoid Arthritis

Ruth Jessen Hickman, MD  |  December 14, 2020

Research in The New England Journal of Medicine has opened new avenues for exploring the pathophysiology of disease flares in rheumatoid arthritis.1 Through longitudinal genomic analysis, researchers have identified a naive B cell signature prior to rheumatoid arthritis flares, as well as a type of mesenchymal cell, that may play an important role in flare…

Filed under:ConditionsResearch RheumRheumatoid Arthritis Tagged with:Flaresgenetics

The Personal Side of COVID-19: A Q&A with Elna Schiopu, MD

Kurt Ullman  |  December 14, 2020

Dr. Schiopu has experienced the COVID-19 pandemic response from both clinical and research perspectives. She recently discussed her experiences with The Rheumatologist.

Filed under:Professional Topics Tagged with:COVID-19telemedicine

Biologics in Rheumatology: Revolution & Perspectives

Lara C. Pullen, PhD  |  December 8, 2020

A great deal of progress has been made in the treatment of rheumatic diseases—from glucocorticoid use to the advent of biologic therapies. Gerd Burmester, MD, discussed this progress and the impact of biologics in this year’s Phillip Hench, MD, Memorial Lecture.

Filed under:ACR ConvergenceBiologics/DMARDsMeeting Reports Tagged with:ACR Convergence 2020biologic drugsBiologicsBiosimilarsmeeting reports

Medicare’s Most Favored Nation Is My Least Favorite Notion!

Angus B. Worthing, MD  |  December 8, 2020

In case you missed it, on Nov. 20, the  Centers for Medicare & Medicaid Services (CMS), a department within the U.S. Department of Health and Human Services, announced that it will overhaul the payment system for Medicare Part B (i.e., infusion) drugs on Jan. 1, 2021. The plan is called the Most Favored Nation (MFN)…

Filed under:Legislation & AdvocacyOpinionProfessional TopicsSpeak Out Rheum Tagged with:MedicareMost Favored Nation

ACR Convergence graphic

Check It Out: Understanding Immune-Related Adverse Events from Immune Checkpoint Inhibitors

Jason Liebowitz, MD, FACR  |  December 4, 2020

Immune checkpoint inhibitors effectively treat malignancy in ways that were not possible just a few years ago, but immune-related adverse events are a potential side effect.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2020immune checkpoint inhibitor (ICI)Immune checkpoint inhibitorsimmunotherapy

Effects of Warfarin on Risk of Hip & Knee Replacement in OA Patients

Michele B. Kaufman, PharmD, BCGP  |  December 4, 2020

The use of warfarin may increase the risk of knee or hip replacement in patients with osteoarthritis (OA), according to research presented during ACR Convergence 2020.

Filed under:ACR ConvergenceDrug UpdatesMeeting Reports Tagged with:ACR Convergence 2020hipkneeOsteoarthritiswarfarin

Resetting Immune Tolerance to Prevent RA

Mary Beth Nierengarten  |  November 24, 2020

Three experts discuss the current evidence on potential pathogenic mechanisms underlying preclinical RA autoimmunity and subsequent active disease.

Filed under:ACR ConvergenceConditionsMeeting ReportsRheumatoid Arthritis Tagged with:ACR Convergence 2020ACR Convergence 2020 – RA

Tofacitinib Promising for Adults with AS

Michele B. Kaufman, PharmD, BCGP  |  November 24, 2020

According to a recent phase 3 study, tofacitinib may be a safe and effective treatment for adult patients with ankylosing spondylitis (AS).

Filed under:Drug Updates

ACR Convergence graphic

Racial Disparities Persist in OA & RA Management

Thomas R. Collins  |  November 19, 2020

From pain management to arthroplasty, African American patients with OA and RA experience worse outcomes than white patients. But the reasons for these health disparities are difficult to parse from socioeconomic and cultural factors.

Filed under:ACR ConvergenceConditionsMeeting ReportsOsteoarthritis and Bone DisordersRheumatoid Arthritis Tagged with:ACR Convergence 2020ACR Convergence 2020 – RA

Food for Thought: On Eating & Inflammation in Rheumatic Disease

Susan Bernstein  |  November 14, 2020

Certain nutrients or dietary patterns may affect inflammation and rheumatic disease risk in certain populations. Recommended nutrients include omega-3 fatty acids found in fish, poultry or nuts. Following a Mediterranean or standard Western diet may affect RA risk too.

Filed under:ACR ConvergenceConditionsMeeting ReportsRheumatoid ArthritisSystemic Lupus Erythematosus Tagged with:ACR Convergence 2020ACR Convergence 2020 – RADietdietary intervention

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