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Search results for: cancer

Transcriptional Programming Research, & a Twist on CAR-T Cell Therapy

Thomas R. Collins  |  March 17, 2018

SAN DIEGO—At the 2017 ACR/ARHP Annual Meeting this past November, an expert said researchers are making progress in identifying drugs that can correct problems with transcriptional programming, which, if perfected, could go a long way toward harnessing more fully the power of genetics knowledge and directing it toward patient care. The session also delved into…

Filed under:ConditionsMeeting Reports Tagged with:ACR/ARHP Annual Meetingpemphigus vulgarisT cell receptortranscriptional programming

Opioids No Better Than NSAIDs for Chronic Back or Arthritis Pain

Lisa Rapaport  |  March 7, 2018

(Reuters Health)—Acetaminophen, ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) are better than opioids at easing the intensity of chronic pain in the back, knees or hips, a U.S. experiment suggests. And opioids are no better than these other drugs at reducing how much pain interferes with daily activities, such as walking, working, sleeping or enjoying…

Filed under:AnalgesicsConditionsDrug UpdatesPain Syndromes Tagged with:Chronic painhiphip painKnee Osteoarthritis (OA)Nonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDsOpioidsosteoarthritis (OA)PainPain Management

Stem Cell Transplantation Benefits Patients with Scleroderma

Lara C. Pullen, PhD  |  February 26, 2018

A recently published study gives new insight into an innovative approach to treating patients with severe scleroderma and internal organ involvement. During the six-year study, researchers demonstrated the durability of the beneficial effects of stem cell transplantation in this patient population. Their data also suggest the treatment has the potential to renormalize the autoreactive immune system…

Filed under:ConditionsSystemic Sclerosis Tagged with:clinical trialsSclerodermastem cell therapystem cell transplantationStem Cells

Gene Signatures in IgG4-Related Disease

Lara C. Pullen, PhD  |  February 20, 2018

Research suggests prednisone treatment can selectively modulate the signatures of regulatory T (Treg) cells, eosinophils and neutrophils in patients with IgG4-related disease. The results show IgG4-related disease may result from an imbalance of immune and inflammatory cells…

Filed under:ConditionsOther Rheumatic Conditions Tagged with:IgG4 related diseaseIgG4-RDregulatory T cellsswellingT cell

Rheumatology Awards, Appointments & Announcements for Feb. 2018

Ann-Marie Lindstrom  |  February 18, 2018

ARHP Member Named to AOTF Board of Trustees (2018–20) Nancy A. Baker, ScD, MPH, OTR, recently took on a new role, joining the American Occupational Therapy Foundation’s (AOTF’s) Board of Trustees. The AOTF is a charitable organization with a mission to support scientific and educational programming for occupational therapy. It provides most of the grants…

Filed under:Profiles Tagged with:Anna KhananianAwardsKaren CostenbaderLupus FoundationMovers & ShakersNancy BakerNaseem Alexa JahdiStevan Gibson

Turbocharge Your Cell Analysis with Mass Cytometry

Thomas R. Collins  |  February 18, 2018

SAN DIEGO—In his doctoral work, Sean Bendall, PhD, assistant professor of pathology and a researcher at Stanford University in Palo Alto, Calif., worked on protein identification and embryonic stem cell biology. That required examining the characteristics of cells—lots of cells. He was struck by how inefficient the process was. “The issue was, every experiment I…

Filed under:Meeting ReportsTechnology Tagged with:ACR/ARHP Annual Meetingcell analysismass cytometry

The Future of Rheumatoid Arthritis Treatment

Thomas R. Collins  |  February 18, 2018

SAN DIEGO—The next era of rheumatoid arthritis (RA) therapy could involve combining anti-tumor necrosis factor (anti-TNF) drugs with drugs that target molecules regulating the destructive potential of synovial fibroblasts, or even with anti-angiogenic drugs, said a pioneer of RA biologics therapy at the 2017 ACR/ARHP Annual Meeting Nov. 3–8. Ravinder N. Maini, MD, professor of…

Filed under:Meeting ReportsRheumatoid Arthritis Tagged with:ACR/ARHP Annual Meetingbig datacombination therapyRheumatoid arthritisTechnology

Experts Discuss the Latest Precision Medicine Research

Susan Bernstein  |  February 18, 2018

SAN DIEGO—In just two decades, precision medicine has gone from futuristic concept to realistic toolbox for clinical physicians. At the 2017 ACR Clinical Research Conference on Nov. 3, the Precision Medicine in Rheumatic Diseases: Hopes and Challenges lecture featured rheumatologists and experts on genetics, genomics, pharmaco­genetics and big data who spoke about the latest research…

Filed under:Meeting ReportsRheumatoid ArthritisSystemic Lupus Erythematosus Tagged with:ACR/ARHP Annual MeetingArthritisbig dataGenetic researchgenomicsLupusPrecision MedicineRheumatoid arthritis

Marijuana for Rheumatology Patients?

Larry Beresford  |  February 17, 2018

SAN DIEGO—What does cannabis offer to the treatment and management of rheumatology patients and the range of pain states they experience? What do we really know about its long-term effects? These are hard questions to answer with currently available data and a reality nuanced by complications cannabis advocates don’t always recognize, according to two experts…

Filed under:Drug UpdatesMeeting Reports Tagged with:ACR/ARHP Annual MeetingcannabisDrug UpdatesmarijuanaPain Management

U.S. Healthcare Spending to Climb 5.3 Percent in 2018

Yasmeen Abutaleb  |  February 14, 2018

WASHINGTON (Reuters)—United States health spending is projected to rise 5.3% in 2018, reflecting rising prices of medical goods and services and higher Medicaid costs, a U.S. government health agency said on Wednesday, an upward trend it forecasts for the next decade. The increase represents a sharp uptick from 2017 spending, which the U.S. Centers for…

Filed under:Professional Topics Tagged with:higher Medicaid costsU.S. Centers for Medicare and Medicaid Services (CMS)U.S. healthcare spending 2018

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