Search results for: denosumab

FDA Issues Safety Alerts for Bisphosphonates & SGLT2 Inhibitors

Michele B. Kaufman, PharmD, BCGP | May 20, 2015

Safety The Food and Drug Administration (FDA) has updated the Warnings and Precautions sections of prescribing information for the bisphosphonate agents, including risedronate sodium tablets and combinations with calcium (Actonel/Atelvia), alendronate and combinations with vitamin D (Binosto/Fosamax), ibandronate (Boniva), etidronate (Didronel) and the RANK-ligand inhibitor denosumab (Prolia/Xgeva).1 This information relates to an increased risk for…

2014 ACR/ARHP Annual Meeting: Rheumatologic Research Uncovers Clues to Therapies

Susan Bernstein | April 1, 2015

Studies explore role of STING pathway in bone remodeling, denosumab to reduce fracture risk, autotaxin’s role in fibrosis, SSc

What’s New in Inflammatory Arthritis?

Thomas R. Collins | June 1, 2014

Rheumatology experts at the ACR’s State-of-the-Art Clinical Symposium in Chicago discuss latest drug therapies, insights into axial spondyloarthritis and bone erosion, repair

New Treatments Needed to Prevent Fractures in Osteoporosis

Ellen M. Field, MD, FACR, CCD | June 1, 2014

Current therapies target pathways of bone remodeling, but rheumatologists say a better understanding of the mechanisms of bone resorption, formation is needed to make an impact

ACR/ARHP Annual Meeting 2012: New Insights into Bone Erosion and Formation Heighten Prospects for Therapies

Thomas R. Collins | April 1, 2013

Studies look at how the balance between osteoclast-mediated bone resorption and osteoblast mediated bone formation is undermined in people with arthritic conditions

ACR/ARHP Annual Meeting 2012: New Treatments and Strategies Emerge for Osteoporosis

Thomas R. Collins | January 1, 2013

Rheumatology experts urge caution in using bisphosphonates to prevent bone loss

Rheumatology Drug Updates

Michele B. Kaufman, PharmD, BCGP | January 1, 2013

Information on new approvals and medication safety rheumatologists need to know

California Rheumatologists Explore Managed Care, Treatment Options

Larry Beresford | July 9, 2012

Advances in SLE, osteoporosis, and RA highlighted at California Rheumatology Alliance meeting.

Space Traveling Mice Provide Insight into Osteoporosis

Richard Quinn | October 7, 2011

Researchers are using the unique, zero-gravity environment to develop therapies for the earthbound

A Duet of Bone and the Immune System

Christian Beyer, MD, and Georg Schett, MD | July 12, 2011

Examining emerging perspectives in osteoimmunology