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Search results for: fever

Is Gout an Autoinflammatory Syndrome After All?

Jason Liebowitz, MD, FACR  |  November 29, 2022

PHILADELPHIA—The term autoinflammatory syndrome was coined by Daniel L. Kastner, MD, PhD, National Institutes of Health (NIH), Bethesda, Md., not long after he discovered that mutations in the gene MEFV, which codes for the protein pyrin, are responsible for familial Mediterranean fever (FMF).1 Early on, the term was meant to signify monogenic conditions in which…

Filed under:ACR ConvergenceConditionsGout and Crystalline ArthritisMeeting Reports Tagged with:ACR Convergence 2022ACR Convergence 2022 – GoutGout

When Rheumatic Disease May Have Affected the Course of Western Civilization

Baljeet Rai, MD, Abhimanyu Amarnani, MD, PhD, Ja-Yoon Uni Choe, MD, Nicole K. Zagelbaum Ward, DO, MPH, & Richard S. Panush, MD, MACP, MACR  |  November 8, 2022

The study of rheumatology (and medicine) in art, history, literature and music is engaging and informative.1-12 In this article, we present some instances when rheumatic and autoimmune diseases in certain individuals may have affected the course of history in Western civilization. Physicians are usually concerned, appropriately, with the effects of illness on the lives of…

Filed under:OpinionProfessional TopicsSpeak Out Rheum Tagged with:History

Changing Treatment Patterns for Patients with JIA

Lara C. Pullen, PhD  |  October 18, 2022

A study from Glerup et al. demonstrated that many patients with juvenile idiopathic arthritis achieved drug-free remission over 18 years of follow-up and that remission rates remained stable between years 8 and 18 of the study period.

Filed under:ConditionsPediatric ConditionsResearch RheumRheumatoid Arthritis Tagged with:ChildrenILARJIAjuvenile idiopathic arthritis (JIA)Pediatric

A Case of Nodular Rash & Painful Joints

Vania Lin, MD, MPH, Rebecca Johnson, MD, & Lisa Suter, MD  |  October 10, 2022

Polyarteritis nodosa (PAN) is a necrotizing vasculitis, predominantly involving medium-sized arteries, that causes systemic disease, and, less commonly, cutaneous-limited disease. The population prevalence for PAN ranges from 2 to 33 per million.1-3 Estimates vary due to the increased recognition and classification of other forms of vasculitides over time and variation in the regional prevalence of…

Filed under:ConditionsVasculitis Tagged with:case reportFellowsFellows Forumpolyarteritis nodosa

Case Report: CPPD Presenting as Pseudosepsis

Hassan Fakhoury, BS, Erin Chew, MD, & Narender Annapureddy, MBBS  |  September 6, 2022

Calcium pyrophosphate crystal deposition disease (CPPD) is an arthritis caused by the accumulation of calcium pyrophosphate crystals. Despite a prevalence of 4–7% among the adult population in Europe and the U.S., it has remained a relatively under-recognized disease owing to its many clinical presentations.1 CPPD may cause an acute mono/oligoarthritis, which may mimic gout or…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:calcium pyrophosphate deposition diseaseGoutpseudosepsisseptic arthritis

Evidence of Things Not Seen: The Match, Vienna & Unknown Unknowns

Philip Seo, MD, MHS  |  August 13, 2022

It is better to be feared than loved. The associate dean of student affairs at my medical school embraced this motto. Although the dean of the medical school was titularly in charge, it was the associate dean who kept the school running. And we all feared her, just a little bit. Without ever raising her…

Filed under:OpinionRheuminationsSpeak Out Rheum Tagged with:DiagnosisexclusionMatchresidency

Clinical Challenges in SLE: Glucocorticoids—How Much Is Too Much?

Samantha C. Shapiro, MD  |  July 22, 2022

Glucocorticoids remain a prominent part of care for many patients with SLE but can have toxic side effects; this EULAR 2022 session discussed one institution’s approach to lower the dosage.

Filed under:ConditionsMeeting ReportsSystemic Lupus Erythematosus Tagged with:GlucocorticoidsHCQHydroxychloroquine (HCQ)prednisoneSLEsystemic lupus erythematosus (SLE)

Teaching Junior Learners in Rheumatology

Ian D. Cooley, MD, & Eli M. Miloslavsky, MD  |  July 13, 2022

Teaching junior learners, such as medical students and residents, is increasingly important in rheumatology. Given the anticiĀ­pated shortage of rheumatologists, attracting more trainees to our field and enhancing knowledge of the rheumatic diseases among physicians in other fields are critical to meeting the needs of our patients.1,2 In addition, clinical reasoning is a vital skill…

Filed under:Education & Training Tagged with:apprenticePreceptorshipteaching

Case Report: Dermato-Neuro Syndrome Recurrence after a Viral Infection

Case Report: Dermato-Neuro Syndrome Recurrence after a Viral Infection

Fazila Aseem, MD, MPH, Alexander D. Jeffs, MD, Enid Y. Sun, MD, MPH, Randaline R. Barnett, MD, Courtney Blodgett, AG-ACNP, Winnie Lau, MD, Casey Olm-Shipman, MD, MS, Matthew F. Sharrock, MD, Rhonda Cadena, MD, Yueh. Z. Lee, MD, PhD, Alfredo C. Rivadeneira, MD, & Clio A. Rubinos, MD, MS  |  July 13, 2022

Scleromyxedema is a primary cutaneous mucinosis characterized by a diffuse and generalized papular skin eruption of mucinous deposits throughout the upper dermis. In addition to dermatologic manifestations, scleromyxedema may involve the cardiopulmonary, gastrointestinal, renal and nervous systems. Dermato-neuro syndrome (DNS) is a rare, severe neurologic complication of scleromyxedema.1,2 The pathogenesis of DNS is unknown, but…

Filed under:ConditionsSystemic Sclerosis Tagged with:case reportCOVID-19Dermato-Neuro SyndromeFellowsScleromyxedema

Case Report: Sweet Syndrome as an Initial Presentation of Crohn’s Disease

Ryan Guerrettaz, MD, Angelo Ciliberti, MD, Rochella Ostrowski, MD, Elise Wolff, DO, Nadia Qureshi, MD, & Ramzan Shahid, MD  |  July 13, 2022

Acute febrile neutrophilic dermatosis, or Sweet syndrome, is an inflammatory disease that classically presents with fever, leukocytosis and tender, erythematous plaques characterized by neutrophilic infiltrates on biopsy. Sweet syndrome has been reported in association with several autoimmune diseases, including inflammatory bowel disease, systemic lupus erythematous, rheumatoid arthritis and sarcoidosis.1 Here, we discuss a case of…

Filed under:Conditions Tagged with:case reportCrohn's diseaseFellowsFellows ForumSweet's syndrome

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