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Search results for: heart disease

More Effective Antifibrotic Therapies for Systemic Sclerosis in Development; Adverse Events A Concern

Susan Bernstein  |  June 14, 2017

Systemic sclerosis (SSc) is a rare disease affecting about 49,000 U.S. adults, and it is strongly associated with high levels of morbidity and mortality.1 Of the few available antifibrotic therapies, none is targeted for SSc. However, reason for optimism exists for antifibrotic treatments in early development and clinical trials, says Jörg H.W. Distler, MD, Heisenberg Professor…

Filed under:ConditionsResearch RheumSystemic Sclerosis Tagged with:adverse eventsantifibrotic therapyClinicaloutcomepatient careResearchrheumatologistrheumatologySclerodermaSystemic sclerosisTreatment

FDA Update: Romosozumab’s Uncertain Future; Plus Tocilizumab Approved for GCA

Michele B. Kaufman, PharmD, BCGP  |  June 9, 2017

Due to possible heart-related side effects, romosozumab is no longer expected to be approved this year for the treatment of osteoporosis…

Filed under:Biologics/DMARDsConditionsDrug UpdatesOsteoarthritis and Bone Disorders Tagged with:FDAFood and Drug AdministrationFracturesgiant cell arteritis (GCA)heartOsteoporosisromosozumabside effecttocilizumab

Diagnosis of Acute Gouty Arthritis Obscured by Anchoring Bias

Diagnosis of Acute Gouty Arthritis Obscured by Anchoring Bias

Sneha Patel, MD, Monica Mohile, MD, & Arundathi Jayatilleke, MD  |  April 19, 2017

A 56-year-old African American man presents to the emergency department with polyarthralgias and a fever of 103ÂşF. One month prior to admission, he presented with right knee pain and swelling. Blood cultures grew S. epidermidis. He was treated for presumed septic arthritis complicated by MSSE bacteremia. He was treated with meropenem and a prolonged course…

Filed under:ConditionsGout and Crystalline Arthritis Tagged with:anchoring biasArthritiscase reportClinicalDiagnosisdiagnostic testingGoutinflammationjointoutcomepatient carepolyarthralgiaRArheumatologistrheumatologyseropositive rheumatoid arthritisTreatment

Rheumatology Case Report: Deep Vein Thrombosis Detected by Point-of-Care Ultrasound

Alvin Lee Day, MD, James W. Fant Jr., MD, & Michael Wagner, MD, FACP, RDMS  |  April 18, 2017

Case A 46-year-old Caucasian female presented to the outpatient rheumatology clinic where she had been followed for several years. Her chief complaint was pain in her right knee, posterior right thigh and right hip that had begun gradually over the previous three weeks. Her past medical history was significant for rheumatoid arthritis (RA), obesity and…

Filed under:ConditionsRheumatoid Arthritis Tagged with:case reportClinicaldeep vein thrombosisDiagnosisDVTimagingoutcomepatient carePOCUSpoint-of-careRARheumatoid arthritisrheumatologyTestTreatmentUltrasoundvenous thromboembolism

How to Leverage Physical Therapy & Technology to Help Patients Stay Fit & Decrease Pain

Carina Stanton  |  March 28, 2017

For patients living with rheumatic diseases, the benefits of physical therapy and exercise cannot be overstated. “Working with a physical therapist provides a chance for careful evaluation of how the patient is moving and experiencing pain,” says Maura Iversen, BSc, PT, DPT, SD, MPH…

Filed under:Conditions Tagged with:Exercise/physical therapyphysical activityPhysical TherapyTechnology

Factors that Influence Biologic Therapy Choices for Patients with Rheumatoid Arthritis

Michele B. Kaufman, PharmD, BCGP  |  March 20, 2017

Recent research analyzed factors influencing the selection of the first-line biologic medications and the real-life factors that lead to switching from those medications to other biologics in treating rheumatoid arthritis (RA). The study compared the use of abatacept and tocilizumab with a tumor necrosis factor alpha inhibitor (TNFi).1,2 Participants were enrolled in the Lombardy Rheumatology…

Filed under:ConditionsDrug UpdatesRheumatoid Arthritis Tagged with:biologic therapiesdrugMedicationpatient carephysicianRheumatic DiseaseRheumatoid arthritisrheumatologistrheumatology

CHARAN RATTANASUPPHASIRI/shutterstock.com

Funding Sources for Scientific Discovery, Medical Research

Simon M. Helfgott, MD  |  March 20, 2017

The Phone Call A phone call in the middle of the night can rattle one’s nerves. The rush of adrenaline sets the heart pounding as our ears brace for what we are about to hear next. A distress call from an elderly parent or a child away at college? Is everyone safe? Or may this…

Filed under:OpinionResearch RheumRheuminationsSpeak Out Rheum Tagged with:discoveryfinancialFundinginvestmentmedicalNational Institutes of HealthPhilanthropyResearchrheumatologysupport

Rheumatology Research Clears Paths to Improved Arthritis Patient Care, Long-Term Health

Susan Bernstein  |  February 15, 2017

WASHINGTON, D.C.—Rheumatology researchers look for next-generation treatments, healthy interventions, and genetic and microbial clues to disease pathogenesis and therapy response, according to new studies presented at a Nov. 15, 2016, press conference at the 2016 ACR/ARHP Annual Meeting. OA & Physical Function How do you know when a patient with knee osteoarthritis (OA) has the…

Filed under:Meeting ReportsResearch Rheum Tagged with:2016 ACR/ARHP Annual MeetingOutcomesPathogenesispatient careResearchRheumatic DiseaserheumatologystudiestherapyTreatment

Pediatric Rheumatologist Shortage Spurs Need for Adult Specialists to Treat Children with Rheumatic Conditions

Thomas R. Collins  |  February 15, 2017

WASHINGTON, D.C.—Addressing a gathering of healthcare providers at the 2016 ACR/ARHP Annual Meeting concurrent session titled, Pediatric Rheumatology for the Adult Rheumatologist, part of the ACR Review Course, expert Sangeeta Sule, MD, PhD, associate professor of pediatrics specializing in rheumatology at Johns Hopkins Hospital in Baltimore, displayed a color-coded map of the U.S. on which…

Filed under:ConditionsMeeting ReportsPediatric Conditions Tagged with:2016 ACR/ARHP Annual Meetingadult rheumatologistChildrenDiagnosisinflammatory conditionsPediatricRheumatic DiseaserheumatologistrheumatologyTreatment

Insights into Drug-Related Interactions in Older Adults

Michele B. Kaufman, PharmD, BCGP  |  February 9, 2017

A study showed that prior hospitalization and the use of multiple medications are risk factors for drug and drug–disease interactions…

Filed under:Drug Updates Tagged with:drug interactionelderlyNonsteroidal anti-inflammatory drugs (NSAIDs)NSAIDs

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