During pro-inflammatory stimulation, a recent study found HIF1α—not Myc—is required for the regulation of glycolysis in macrophages. Researchers examined macrophages and the distinct transcriptional programs engaged in response to mitogenic and pro-inflammatory stimulation…
For rheumatologists, research is important, but some clinical trials may not be worth collaborating on. In a recent interview, Hermine Brunner, MD, MSc, MBA, FACR, outlined important considerations to make when deciding to participate in a clinical trial to ensure a good fit…
Discussing aching joints, sore muscles and tender limbs is all in our day’s work. We are rheumatologists; we deal in misery. But trying to parse the true meaning of these terms is among the most vexing of clinical challenges.
Settling into room 501 at Maine Medical Center, Mrs. N was on her way to the bathroom when she felt it coming on. One moment she was okay; the next, her chest felt damp and cold, even as her face flushed and her temperature spiked. Her forehead glistened beads of warm sweat. She felt the…
A study that found men with rheumatoid arthritis (RA) died from respiratory-related illness nearly three times as often as the general population could provide insight into possible treatment options and lifestyle changes that would help them live longer. The Study Researchers at the Veterans Affairs Nebraska-Western Iowa Health Care System and University of Nebraska Medical…
Slow, slow, quick, quick. Don Miller, PharmD, has repeated that phrase to himself countless times over the past 40 years. Since the 1980s, Dr. Miller, a professor of pharmacy practice in the College of Health Professions at North Dakota State University (NDSU), has been a competitive ballroom dancer. Repeating that phrase is common to all…
Currier McEwen, MD, was a truly remarkable rheumatologist, accomplishing more than even the best of us could imagine. He is even more recognized in the horticulture community as a hybridizer of flowers. He was born Osceola Currier McEwen on April Fool’s Day, 1902, in Newark, N.J., and died in 2003, at the age of 101….
SAN FRANCISCO—Post-menopausal women with osteoporosis, previously treated with oral bisphosphonates, had greater increases in bone density when taking denosumab compared with zoledronic acid over a year’s time, according to a study presented at the 2015 ACR/ARHP Annual Meeting. The findings were discussed in the Discovery 2015 plenary session, which focused on new research. In the…
Many rheumatologists chose the profession because they wanted to delve more deeply into rheumatic diseases than internal medicine calls for. “For most, this level of specialization is sufficient and worthy of a lifelong devotion and commitment,” says S. Sam Lim, MD, MPH, associate professor, Medicine and Epidemiology, Emory University School of Medicine, Atlanta. “However, some…
Similar to other healthcare professionals, I have been required to use ICD-10 codes for the past several months. Unfortunately, I have been unable to discern any improvement in my patient care, but perhaps I have not used the codes long enough. Certainly, healthcare administrators and statisticians assure me there are several advantages of ICD-10 over…